Mediators of the association between depression and role functioning

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• dc.contributor.author Buist-Bouwman, M.A.
• dc.contributor.author Ormel, Johan
• dc.contributor.author de Graaf, Ron
• dc.contributor.author de Jonge, Peter
• dc.contributor.author van Sonderen, Eric
• dc.contributor.author Alonso Caballero, Jordi
• dc.contributor.author Bruffaerts, Ronny
• dc.contributor.author Vollebergh, Wilma
• dc.contributor.author ESEMeD/MHEDEA 2000 investigators
• dc.date.accessioned 2019-03-14T07:33:31Z
• dc.date.available 2019-03-14T07:33:31Z
• dc.date.issued 2008
• dc.description.abstract OBJECTIVE: While the adverse effect of Major Depressive Episode on role functioning is well established, the exact pathways remain unclear. METHOD: Data from The European Study of the Epidemiology of Mental Disorders, a cross-sectional survey including 21 425 adults from six European countries, were used to assess 12-month depression (Composite International Diagnostic Interview), activity limitations and role functioning in the past 30 days (Disability Assessment Schedule). An a priori model based on the World Health Organization's International Classification of Functioning, Disability and Health was designed and a structural equation model for categorical and ordinal data was used (MPlus) to estimate the extent to which six limitations mediated the association between depression and role functioning. RESULTS: The unadjusted association between depression and role functioning was strong (0.43; SE = 0.04). In the best-fitting model, only concentration and attention problems and embarrassment mediated a significant amount of association (direct effect dropped to 0.17; SE = 0.10, which was no longer significant). CONCLUSIONS: Targeting cognition and embarrassment in treatment could help reduce depression-associated role disfunctioning.
• dc.description.sponsorship These activities were supported by the United States National Institute of Mental Health (R01MH070884), the John D. and Catherine T. MacArthur Foundation, the Pfizer Foundation, the US Public Health Service (R13-MH066849, R01-MH069864 and R01 DA016558), the Fogarty International Center (FIRCA R01-TW006481). The ESEMeD project is funded by the European Commission (Contracts QLG5-1999-01042; SANCO 2004123), the Piedmont Region (Italy), Fondo de Investigación Sanitaria, Instituto de Salud Carlos III, Spain (FIS 00/0028), Ministerio de Ciencia y Tecnología, Spain (SAF 2000-158-CE), Departament de Salut, Generalitat de Catalunya, Spain
• dc.format.mimetype application/pdf
• dc.identifier.citation Buist-Bouwman MA, Ormel J, de Graaf R, de Jonge P, van Sonderen E, Alonso J et al. Mediators of the association between depression and role functioning. Acta Psychiatr Scand. 2008 Dec;118(6):451-8. DOI: 10.1111/j.1600-0447.2008.01285.x
• dc.identifier.doi http://dx.doi.org/10.1111/j.1600-0447.2008.01285.x
• dc.identifier.issn 0001-690X
• dc.identifier.uri http://hdl.handle.net/10230/36822
• dc.language.iso eng
• dc.publisher Wiley-VCH Verlag
• dc.relation.ispartof Acta Psychiatrica Scandinavica. 2008 Dec;118(6):451-8
• dc.relation.projectID info:eu-repo/grantAgreement/ES/1PN/SAF2000-158-CE
• dc.rights © 2008 M.A. Buist-Bouwman et al. Mediators of the association between depression and role functioning. M.A. Buist-Bouwman et al. Acta Psychiatrica Scandinavica, vol. 118, núm. 6
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.subject.other Depressió psíquica
• dc.title Mediators of the association between depression and role functioning
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/acceptedVersion