A longitudinal study of environmental tobacco smoke exposure in children: parental self reports versus age dependent biomarkers
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- dc.contributor.author Puig, Carmeca
- dc.contributor.author García Algar, Oscarca
- dc.contributor.author Monleón, Tonica
- dc.contributor.author Pacifici, Robertaca
- dc.contributor.author Zuccaro, Piergiorgioca
- dc.contributor.author Sunyer Deu, Jordica
- dc.contributor.author Figueroa, Ceciliaca
- dc.contributor.author Pichini, Simonaca
- dc.contributor.author Vall Combelles, Oriolca
- dc.date.accessioned 2012-05-08T08:13:50Z
- dc.date.available 2012-05-08T08:13:50Z
- dc.date.issued 2008ca
- dc.description.abstract Background: Awareness of the negative effects of smoking on children's health prompted a decrease in the self-reporting of parental tobacco use in periodic surveys from most industrialized countries. Our aim is to assess changes between ETS exposure at the end of pregnancy and at 4 years of age determined by the parents' self-report and measurement of cotinine in age related biological matrices./nMethods: The prospective birth cohort included 487 infants from Barcelona city (Spain). Mothers were asked about maternal and household smoking habit. Cord serum and children's urinary cotinine were analyzed in duplicate using a double antibody radioimmunoassay. Results: At 4 years of age, the median urinary cotinine level in children increased 1.4 or 3.5 times when father or mother smoked, respectively. Cotinine levels in children's urine statistically differentiated children from smoking mothers (Geometric Mean (GM) 19.7 ng/ml; 95% CI 16.83–23.01) and exposed homes (GM 7.1 ng/ml; 95% CI 5.61–8.99) compared with non-exposed homes (GM 4.5 ng/ml; 95% CI 3.71–5.48). Maternal self-reported ETS exposure in homes declined in the four year span between the two time periods from 42.2% to 31.0% (p < 0.01). Nevertheless, most of the children considered non-exposed by their mothers had detectable levels of cotinine above 1 ng/mL in their urine./nConclusion: We concluded that cotinine levels determined in cord blood and urine, respectively, were useful for categorizing the children exposed to smoking and showed that a certain increase in ETS exposure during the 4-year follow-up period occurred.
- dc.format.mimetype application/pdfca
- dc.identifier.citation Puig C, Garcia-Algar O, Monleon T, Pacifici R, Zuccaro P, Sunyer J, Figueroa C, Pichini S, Vall O. A longitudinal study of environmental tobacco smoke exposure in children: parental self reports versus age dependent biomarkers. BMC Public Health. 2008; 8: 47. DOI: 10.1186/1471-2458-8-47ca
- dc.identifier.doi http://dx.doi.org/10.1186/1471-2458-8-47
- dc.identifier.issn 1471-2458ca
- dc.identifier.uri http://hdl.handle.net/10230/16417
- dc.language.iso engca
- dc.publisher BioMed Centralca
- dc.relation.ispartof BMC Public Health. 2008; 8: 47
- dc.rights (c) 2008 Puig et al. Creative Commons Attribution Licenseca
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/2.0/
- dc.subject.other Hàbit de fumar
- dc.subject.other Tabaquisme passiu en els infants
- dc.title A longitudinal study of environmental tobacco smoke exposure in children: parental self reports versus age dependent biomarkersca
- dc.type info:eu-repo/semantics/articleca
- dc.type.version info:eu-repo/semantics/publishedVersion