The Genotype-Tissue Expression (GTEx) project
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- dc.contributor.author GTEx Consortiumca
- dc.contributor.author Lonsdale, Johnca
- dc.contributor.author Guigó Serra, Rodericca
- dc.contributor.author Monlong, Jeanca
- dc.contributor.author Sammeth, Michaelca
- dc.contributor.author Moore, Helen F.ca
- dc.date.accessioned 2015-02-05T08:37:25Z
- dc.date.available 2015-02-05T08:37:25Z
- dc.date.issued 2013ca
- dc.description.abstract Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain unknown. Most associated variants are not correlated with protein-coding changes, suggesting that polymorphisms in regulatory regions probably contribute to many disease phenotypes. Here we describe the Genotype-Tissue Expression (GTEx) project, which will establish a resource database and associated tissue bank for the scientific community to study the relationship between genetic variation and gene expression in human tissues.
- dc.format.mimetype application/pdfca
- dc.identifier.citation GTEx Consortium. The Genotype-Tissue Expression (GTEx) project. Nat Genet. 2013;45(6):580-5. DOI: 10.1038/ng.2653ca
- dc.identifier.doi http://dx.doi.org/10.1038/ng.2653
- dc.identifier.issn 1061-4036ca
- dc.identifier.uri http://hdl.handle.net/10230/23095
- dc.language.iso engca
- dc.publisher Nature Publishing Groupca
- dc.relation.ispartof Nature Genetics. 2013;45(6):580-5
- dc.rights http://dx.doi.org/10.1038/ng.2653. This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported Licenseca
- dc.rights.accessRights info:eu-repo/semantics/openAccessca
- dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/3.0/
- dc.subject.other Expressió gènica
- dc.subject.other Genomes
- dc.title The Genotype-Tissue Expression (GTEx) projectca
- dc.type info:eu-repo/semantics/articleca
- dc.type.version info:eu-repo/semantics/publishedVersionca