Computed tomography-guided cryoablation in treating adrenal metastases: a retrospective single-center study

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  • dc.contributor.author Pusceddu, Claudio
  • dc.contributor.author Faiella, Eliodoro
  • dc.contributor.author Cau, Claudio
  • dc.contributor.author Rinaldi, Pierluigi
  • dc.contributor.author Melis, Luca
  • dc.contributor.author Marsico, Salvatore
  • dc.date.accessioned 2025-11-11T15:02:08Z
  • dc.date.available 2025-11-11T15:02:08Z
  • dc.date.issued 2025
  • dc.date.updated 2025-11-11T15:02:08Z
  • dc.description.abstract Purpose: To assess the effectiveness and safety of computed tomography (CT)-guided cryoablation for treating adrenal metastases (AMs). Methods: This study included 12 patients treated with 13 CT-guided cryoablation procedures for AMs between 2016 and 2020. Patients were selected based on specific criteria, including tumor size ≤5 cm and suitability for surgery. Procedures were performed by expert radiologists, with comprehensive monitoring for complications and regular post-treatment evaluations. Results: The primary technical success rate was 91.7%, with a secondary success rate of 100% following repeat procedures. Over an 8-24-month follow-up period, local tumor recurrence was observed in 16.7% of patients, and systemic progression occurred in five (41.6%) patients. The average overall survival duration was 26.4 ± 5.6 months. Conclusion: CT-guided cryoablation is a feasible and effective treatment option for AMs, demonstrating high technical success rates and manageable complications. Clinical significance: This study highlights CT-guided cryoablation as a promising treatment for AMs, offering a minimally invasive alternative to surgery with good local control and safety profile. Further research, including multi-center studies, is needed to confirm these findings.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Pusceddu C, Faiella E, Cau C, Rinaldi P, Melis L, Marsico S. Computed tomography-guided cryoablation in treating adrenal metastases: a retrospective single-center study. Diagn Interv Radiol. 2025 Jul 8;31(4):372-6. DOI: 10.4274/dir.2024.242956
  • dc.identifier.doi http://dx.doi.org/10.4274/dir.2024.242956
  • dc.identifier.issn 1305-3825
  • dc.identifier.uri http://hdl.handle.net/10230/71859
  • dc.language.iso eng
  • dc.publisher Turkish Society of Radiology
  • dc.relation.ispartof Diagnostic and Interventional Radiology. 2025;31(4):372-6
  • dc.rights Copyright@Author(s) - Available online at dirjournal.org. Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/).
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
  • dc.subject.keyword Adrenal glands
  • dc.subject.keyword Cryotherapy
  • dc.subject.keyword Computed tomography
  • dc.subject.keyword Local treatment
  • dc.subject.keyword Oncology
  • dc.title Computed tomography-guided cryoablation in treating adrenal metastases: a retrospective single-center study
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion