Antimicrobial resistance in Gram-negative bacilli in Spain: an experts’ view

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  • dc.contributor.author Retamar-Gentil, Pilar
  • dc.contributor.author Cantón, Rafael
  • dc.contributor.author Abril López De Medrano, Vicente
  • dc.contributor.author Barberán, José
  • dc.contributor.author Canut Blasco, Andrés
  • dc.contributor.author Dueñas Gutiérrez, Carlos
  • dc.contributor.author García Vidal, Carolina
  • dc.contributor.author Larrosa Escartín, Nieves
  • dc.contributor.author Lora-Tamayo, Jaime
  • dc.contributor.author Martínez Marcos, Francisco Javier
  • dc.contributor.author Martín Ruíz, Carlos
  • dc.contributor.author Pasquau, Juan
  • dc.contributor.author Rascado, Pedro
  • dc.contributor.author Sanz Peláez, Óscar
  • dc.contributor.author Yagüe Girao, Genoveva
  • dc.contributor.author Horcajada Gallego, Juan Pablo
  • dc.date.accessioned 2023-06-20T10:30:05Z
  • dc.date.available 2023-06-20T10:30:05Z
  • dc.date.issued 2023
  • dc.description.abstract Antibiotic resistance in Gram-negative bacilli poses a serious problem for public health. In hospitals, in addition to high mortality rates, the emergence and spread of resistance to practically all antibiotics restricts therapeutic options against serious and frequent infections. The aim of this work is to present the views of a group of experts on the following aspects regarding resistance to antimicrobial agents in Gram-negative bacilli: 1) the current epidemiology in Spain, 2) how it is related to local clinical practice and 3) new therapies in this area, based on currently available evidence. After reviewing the most noteworthy evidence, the most relevant data on these three aspects were presented at a national meeting to 99 experts in infectious diseases, clinical microbiology, internal medicine, intensive care medicine, anaesthesiology and hospital pharmacy. Subsequent local debates among these experts led to conclusions in this matter, including the opinion that the approval of new antibiotics makes it necessary to train the specialists involved in order to optimise how they use them and improve health outcomes; microbiology laboratories in hospitals must be available throughout a continuous timetable; all antibiotics must be available when needed and it is necessary to learn to use them correctly; and the Antimicrobial Stewardship Programs (ASP) play a key role in quickly allocating the new antibiotics within the guidelines and ensure appropriate use of them.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Retamar-Gentil P, Cantón R, Abril V, Barberán J, Canut A, Dueñas C, et al. Antimicrobial resistance in Gram-negative bacilli in Spain: an experts’ view. Revista española de quimioterapia. 2023;36(1):65-81. DOI: 10.37201/req/119.2022
  • dc.identifier.doi http://dx.doi.org/10.37201/req/119.2022
  • dc.identifier.issn 0214-3429
  • dc.identifier.uri http://hdl.handle.net/10230/57276
  • dc.language.iso eng
  • dc.publisher Sociedad Española de Quimioterapia
  • dc.relation.ispartof Revista española de quimioterapia. 2023;36(1):65-81
  • dc.rights © The Author 2022. Published by Sociedad Española de Quimioterapia. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)(https://creativecommons.org/licenses/by-nc/4.0/).
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
  • dc.subject.keyword Antimicrobial resistance
  • dc.subject.keyword Multiresistance
  • dc.subject.keyword Enterobacterales
  • dc.title Antimicrobial resistance in Gram-negative bacilli in Spain: an experts’ view
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion