An increase in visceral fat is associated with a decrease in the taste and olfactory capacity

Fernandez-Garcia, Jose Carlos; Alcaide, Juan; Santiago-Fernandez, Concepcion; Roca-Rodriguez, M.M.; Agüera, Zaida; Baños, Rosa M.; Botella, Cristina; Torre Fornell, Rafael de la; Fernández Real, Jose M.; Frühbeck, Gema; Gómez Ambrosi, Javier; Jiménez Murcia, Susana; Menchón, José M.; Casanueva, Felipe F.; Fernández Aranda, Fernando; Tinahones Madueño, Francisco José; Garrido-Sanchez, Lourdes

An increase in visceral fat is associated with a decrease in the taste and olfactory capacity

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dc.contributor.author Fernandez-Garcia, Jose Carlosca
dc.contributor.author Alcaide, Juanca
dc.contributor.author Santiago-Fernandez, Concepcionca
dc.contributor.author Roca-Rodriguez, M.M.ca
dc.contributor.author Agüera, Zaidaca
dc.contributor.author Baños, Rosa M.ca
dc.contributor.author Botella, Cristinaca
dc.contributor.author Torre Fornell, Rafael de laca
dc.contributor.author Fernández Real, Jose M.ca
dc.contributor.author Frühbeck, Gemaca
dc.contributor.author Gómez Ambrosi, Javierca
dc.contributor.author Jiménez Murcia, Susanaca
dc.contributor.author Menchón, José M.ca
dc.contributor.author Casanueva, Felipe F.ca
dc.contributor.author Fernández Aranda, Fernandoca
dc.contributor.author Tinahones Madueño, Francisco Joséca
dc.contributor.author Garrido-Sanchez, Lourdesca
dc.date.accessioned 2017-05-26T07:52:23Z
dc.date.available 2017-05-26T07:52:23Z
dc.date.issued 2017
dc.description.abstract Introduction: Sensory factors may play an important role in the determination of appetite and food choices. Also, some adipokines may alter or predict the perception and pleasantness of specific odors. We aimed to analyze differences in smell–taste capacity between females with different weights and relate them with fat and fat-free mass, visceral fat, and several adipokines. Materials and methods: 179 females with different weights (from low weight to morbid obesity) were studied. We analyzed the relation between fat, fat-free mass, visceral fat (indirectly estimated by bioelectrical impedance analysis with visceral fat rating (VFR)), leptin, adiponectin and visfatin. The smell and taste assessments were performed through the "Sniffin’ Sticks" and "Taste Strips" respectively. Results: We found a lower score in the measurement of smell (TDI-score (Threshold, Discrimination and Identification)) in obese subjects. All the olfactory functions measured, such as threshold, discrimination, identification and the TDI-score, correlated negatively with age, body mass index (BMI), leptin, fat mass, fat-free mass and VFR. In a multiple linear regression model, VFR mainly predicted the TDI-score. With regard to the taste function measurements, the normal weight subjects showed a higher score of taste functions. However a tendency to decrease was observed in the groups with greater or lesser BMI. In a multiple linear regression model VFR and age mainly predicted the total taste scores. Discussion: We show for the first time that a reverse relationship exists between visceral fat and sensory signals, such as smell and taste, across a population with different body weight conditions.
dc.description.sponsorship Instituto Salud Carlos III (FIS PI14/00290) CIBERObn and CIBERSAM are both initiatives of ISCIII, Spain. Fondos Europeos de Desarrollo Regional (FEDER) Ministerio de Economía y Competitividad (PSI2015-68701-R) Jose C. Fernández-García is recipient of a research contract from Servicio Andaluz de Salud (SAS) (B-0033-2014). L. Garrido-Sánchez is supported by a fellowship from the Fondo de Investigación Sanitaria (FIS) “Miguel Servet I” MS13/00188-CP13/00188.
dc.format.mimetype application/pdfca
dc.identifier.citation Fernandez-Garcia JC, Alcaide J, Santiago-Fernandez C, Roca-Rodriguez MM, Agüera Z, Baños R et al. An increase in visceral fat is associated with a decrease in the taste and olfactory capacity. PLoS ONE. 2017:12(3);e0173588. DOI: 10.1371/journal.pone.0171204
dc.identifier.doi http://dx.doi.org/10.1371/journal.pone.0171204
dc.identifier.issn 1932-6203
dc.identifier.uri http://hdl.handle.net/10230/32164
dc.language.iso eng
dc.publisher Public Library of Science (PLoS)ca
dc.relation.ispartof PLoS ONE. 2017:12(3);e0173588
dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/PSI2015-68701-R
dc.rights © 2017 Fernandez-Garcia et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject.keyword Taste
dc.subject.keyword Fats
dc.subject.keyword Leptin
dc.subject.keyword Obesity
dc.subject.keyword Body mass index
dc.subject.keyword Smell
dc.subject.keyword Gustatory system
dc.subject.keyword Morbid obesity
dc.title An increase in visceral fat is associated with a decrease in the taste and olfactory capacityca
dc.type info:eu-repo/semantics/article
dc.type.version info:eu-repo/semantics/publishedVersion

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