Cost benefit of implementation of risk stratification models for adult spinal deformity surgery

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• dc.contributor.author Passias, Peter G.
• dc.contributor.author Serra Burriel, Miquel
• dc.contributor.author International Spine Study Group
• dc.date.accessioned 2025-04-16T06:40:53Z
• dc.date.available 2025-04-16T06:40:53Z
• dc.date.issued 2025
• dc.description.abstract Study Design/Setting: Retrospective cohort study. Objective: Assess the extent to which defined risk factors of adverse events are drivers of cost-utility in spinal deformity (ASD) surgery. Methods: ASD patients with 2-year (2Y) data were included. Tertiles were used to define high degrees of frailty, sagittal deformity, blood loss, and surgical time. Cost was calculated using the Pearl Diver registry and cost-utility at 2Y was compared between cohorts based on the number of risk factors present. Statistically significant differences in cost-utility by number of baseline risk factors were determined using ANOVA, followed by a generalized linear model, adjusting for clinical site and surgeon, to assess the effects of increasing risk score on overall cost-utility. Results: By 2 years, 31% experienced a major complication and 23% underwent reoperation. Patients with ≤2 risk factors had significantly less major complications. Patients with 2 risk factors improved the most from baseline to 2Y in ODI. Average cost increased by $8234 per risk factor (R2 = .981). Cost-per-QALY at 2Y increased by $122,650 per risk factor (R2 = .794). Adjusted generalized linear model demonstrated a significant trend between increasing risk score and increasing cost-utility (r2 = .408, P < .001). Conclusions: The number of defined patient-specific and surgical risk factors, especially those with greater than two, were associated with increased index surgical costs and diminished cost-utility. Efforts to optimize patient physiology and minimize surgical risk would likely reduce healthcare expenditures and improve the overall cost-utility profile for ASD interventions. Level of evidence: III
• dc.format.mimetype application/pdf
• dc.identifier.citation Passias PG, Williamson TK, Kummer NA, Pellisé F, Lafage V, Lafage R, et al. Cost benefit of implementation of risk stratification models for adult spinal deformity surgery. Global Spine J. 2025;15(2):818-30. DOI: 10.1177/21925682231212966
• dc.identifier.doi http://dx.doi.org/10.1177/21925682231212966
• dc.identifier.issn 2192-5682
• dc.identifier.uri http://hdl.handle.net/10230/70150
• dc.language.iso eng
• dc.publisher SAGE Publications
• dc.relation.ispartof Global Spine Journal. 2025;15(2):818-30
• dc.rights This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
• dc.subject.keyword Adult spinal deformity
• dc.subject.keyword Spine
• dc.subject.keyword Cost-utility
• dc.subject.keyword Risk stratification
• dc.subject.keyword Major complications
• dc.subject.keyword Mechanical failure
• dc.subject.keyword Surgical factors
• dc.title Cost benefit of implementation of risk stratification models for adult spinal deformity surgery
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion