Diagnostic accuracy and detection rate of glaucoma screening with optic disk photos, optical coherence tomography images, and telemedicine
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- dc.contributor.author Antón López, Alfonso
- dc.contributor.author Nolivos, Karen
- dc.contributor.author Pazos López, Marta
- dc.contributor.author Fatti, Gianluca
- dc.contributor.author Ayala, Miriam Eleonora
- dc.contributor.author Martínez-Prats, Elena
- dc.contributor.author Peral, Oscar
- dc.contributor.author Poposki, Vladimir
- dc.contributor.author Tsiroukis, Evangelos
- dc.contributor.author Morilla-Grasa, Antonio
- dc.contributor.author Comas Serrano, Mercè
- dc.contributor.author Castells, Xavier
- dc.date.accessioned 2022-09-28T06:15:42Z
- dc.date.available 2022-09-28T06:15:42Z
- dc.date.issued 2021
- dc.description.abstract Purpose: The aim of this study was to evaluate the diagnostic accuracy of optical coherence tomography (OCT) and retinography in the detection of glaucoma through a telemedicine program. Methods: A population-based sample of 4113 persons was randomly selected. The screening examination included a fundus photograph and OCT images. Images were evaluated on a deferred basis. All participants were then invited to a complete glaucoma examination, including gonioscopy, visual field, and dilated fundus examination. The detection rate, sensitivity, specificity, and positive and negative predictive values were calculated. Results: We screened 1006 persons. Of these, 201 (19.9%) were classified as glaucoma suspects; 20.4% were identified only by retinographs, 11.9% only by OCT images, and 46.3% by both. On ophthalmic examination at the hospital (n = 481), confirmed glaucoma was found in 58 (12.1%), probable glaucoma in 76 (15.8%), and ocular hypertension in 10 (2.1%), and no evidence of glaucoma was found in 337 (70.0%). The detection rate for confirmed or probable glaucoma was 9.2%. Sensitivity ranged from 69.4% to 86.2% and specificity from 82.1% to 97.4%, depending on the definition applied. Conclusions: The combination of OCT images and fundus photographs yielded a detection rate of 9.2% in a population-based screening program with moderate sensitivity, high specificity, and predictive values of 84-96%.
- dc.format.mimetype application/pdf
- dc.identifier.citation Anton A, Nolivos K, Pazos M, Fatti G, Ayala ME, Martínez-Prats E, Peral O, Poposki V, Tsiroukis E, Morilla-Grasa A, Comas M, Castells X. Diagnostic accuracy and detection rate of glaucoma screening with optic disk photos, optical coherence tomography images, and telemedicine. J Clin Med. 2021 Dec 31;11(1):216. DOI: 10.3390/jcm11010216
- dc.identifier.doi http://dx.doi.org/10.3390/jcm11010216
- dc.identifier.issn 2077-0383
- dc.identifier.uri http://hdl.handle.net/10230/54185
- dc.language.iso eng
- dc.publisher MDPI
- dc.relation.ispartof J Clin Med. 2021 Dec 31;11(1):216
- dc.rights © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri https://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Glaucoma
- dc.subject.keyword Optical coherence tomography
- dc.subject.keyword Retinography
- dc.subject.keyword Screening
- dc.subject.keyword Telemedicine
- dc.title Diagnostic accuracy and detection rate of glaucoma screening with optic disk photos, optical coherence tomography images, and telemedicine
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion