Sleep duration and napping in relation to colorectal and gastric cancer in the MCC-Spain study
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- dc.contributor.author Papantoniou, Kyriaki, 1983-
- dc.contributor.author Castaño Vinyals, Gemma
- dc.contributor.author Espinosa Díaz, Ana
- dc.contributor.author Turner, Michelle C.
- dc.contributor.author Kogevinas, Manolis
- dc.contributor.author Moreno, Víctor
- dc.date.accessioned 2022-06-03T06:24:36Z
- dc.date.available 2022-06-03T06:24:36Z
- dc.date.issued 2021
- dc.description.abstract Sleep duration is a novel and potentially modifiable risk factor for cancer. We evaluated the association of self-reported sleep duration and daytime napping with odds of colorectal and gastric cancer. We included 2008 incident colorectal cancer cases, 542 gastric cancer cases and 3622 frequency-matched population controls, recruited in the MCC-Spain case-control study (2008-2013). Sleep information, socio-demographic and lifestyle characteristics were obtained through personal interviews. Multivariable adjusted logistic regression models were used to estimate odds ratios (OR) with 95% confidence intervals (CI) for cancer, across categories of sleep duration (≤ 5, 6, 7, 8, ≥ 9 hours/day), daytime napping frequency (naps/week) and duration (minutes/nap). Compared to 7 hours of sleep, long sleep was associated with increased odds of colorectal (OR≥9 hours: 1.59; 95%CI 1.30-1.94) and gastric cancer (OR≥9 hours: 1.95; 1.37-2.76); short sleep was associated with increased odds of gastric cancer (OR≤5 hours: 1.32; 0.93-1.88). Frequent and long daytime naps increased the odds of colorectal (OR6-7 naps/week, ≥30 min: 1.32; 1.14-1.54) and gastric cancer (OR6-7 naps/week, ≥30 min: 1.56; 1.21-2.02). Effects of short sleep and frequent long naps were stronger among participants with night shift-work history. Sleep and circadian disruption may jointly play a role in the etiology of colorectal and gastric cancer.
- dc.format.mimetype application/pdf
- dc.identifier.citation Papantoniou K, Castaño-Vinyals G, Espinosa A, Turner MC, Martín-Sánchez V, Casabonne D et al. Sleep duration and napping in relation to colorectal and gastric cancer in the MCC-Spain study. Sci Rep. 2021 Jun 3;11(1):11822. DOI: 10.1038/s41598-021-91275-3
- dc.identifier.doi http://dx.doi.org/10.1038/s41598-021-91275-3
- dc.identifier.issn 2045-2322
- dc.identifier.uri http://hdl.handle.net/10230/53372
- dc.language.iso eng
- dc.publisher Nature Research
- dc.relation.ispartof Sci Rep. 2021 Jun 3;11(1):11822
- dc.rights © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Cancer
- dc.subject.keyword Gastroenterology
- dc.subject.keyword Risk factors
- dc.title Sleep duration and napping in relation to colorectal and gastric cancer in the MCC-Spain study
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion