Contrast-enhanced breast imaging: Current status and future challenges

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  • dc.contributor.author van Nijnatten, Thiemo J. A.
  • dc.contributor.author Morscheid, Stephanie
  • dc.contributor.author Baltzer, Pascal A. T.
  • dc.contributor.author Clauser, Paola
  • dc.contributor.author Alcantara da Silva, Rodrigo
  • dc.contributor.author Kuhl, Christiane K.
  • dc.contributor.author Wildberger, Joachim E.
  • dc.date.accessioned 2024-10-15T06:20:03Z
  • dc.date.available 2024-10-15T06:20:03Z
  • dc.date.issued 2024
  • dc.description.abstract Background: Contrast-enhanced breast MRI and recently also contrast-enhanced mammography (CEM) are available for breast imaging. The aim of the current overview is to explore existing evidence and ongoing challenges of contrast-enhanced breast imaging. Methods: This narrative provides an introduction to the contrast-enhanced breast imaging modalities breast MRI and CEM. Underlying principle, techniques and BI-RADS reporting of both techniques are described and compared, and the following indications and ongoing challenges are discussed: problem-solving, high-risk screening, supplemental screening in women with extremely dense breast tissue, breast implants, neoadjuvant systemic therapy (NST) response monitoring, MRI-guided and CEM- guided biopsy. Results: Technique and reporting for breast MRI are standardised, for the newer CEM standardisation is in progress. Similarly, compared to other modalities, breast MRI is well established as superior for problem-solving, screening women at high risk, screening women with extremely dense breast tissue or with implants; and for monitoring response to NST. Furthermore, MRI-guided biopsy is a reliable technique with low long-term false negative rates. For CEM, data is as yet either absent or limited, but existing results in these settings are promising. Conclusion: Contrast-enhanced breast imaging achieves highest diagnostic performance and should be considered essential. Of the two contrast-enhanced modalities, evidence of breast MRI superiority is ample, and preliminary results on CEM are promising, yet CEM warrants further study.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation van Nijnatten TJA, Morscheid S, Baltzer PAT, Clauser P, Alcantara R, Kuhl CK, et al. Contrast-enhanced breast imaging: Current status and future challenges. Eur J Radiol. 2024 Feb;171:111312. DOI: 10.1016/j.ejrad.2024.111312
  • dc.identifier.doi http://dx.doi.org/10.1016/j.ejrad.2024.111312
  • dc.identifier.issn 0720-048X
  • dc.identifier.uri http://hdl.handle.net/10230/61396
  • dc.language.iso eng
  • dc.publisher Elsevier
  • dc.relation.ispartof Eur J Radiol. 2024 Feb;171:111312
  • dc.rights © 2024 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by/4.0/
  • dc.subject.keyword Breast MRI
  • dc.subject.keyword Breast imaging
  • dc.subject.keyword Contrast-enhanced mammography
  • dc.title Contrast-enhanced breast imaging: Current status and future challenges
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion