Bioanalytical techniques in discrimination between therapeutic and abusive use of drugs in sport
Mostra el registre complet Registre parcial de l'ítem
- dc.contributor.author Ventura Alemany, Rosaca
- dc.contributor.author Matabosch Geronès, Xavierca
- dc.contributor.author Segura, Joanca
- dc.date.accessioned 2016-06-01T10:17:53Z
- dc.date.issued 2016
- dc.description.abstract The discrimination between therapeutic and abusive use of drugs in sports is performed using threshold concentrations or reporting levels, and the detection of the substances in a sample is only reported as an adverse analytical finding when the concentration exceeds the threshold or the reporting level. In this paper, the strategies of discrimination and the analytical methods used for the main groups of substances where the distinction is needed (β-2 agonists, ephedrines, glucocorticoids and morphine) will be reviewed. Nowadays, LC-MS is the method of choice for the analysis of these substances and, in most of the cases, a simple dilution of the urine sample is performed before the chromatographic analysis.ca
- dc.description.sponsorship The financial support received from Consell Català de l’Esport and DIUE (2014 651 SGR 692) (Generalitat de Catalunya, Spain) and the World Antidoping Agency 652 (grants 13D22RV and 14D06RV) is acknowledged
- dc.format.mimetype application/pdfca
- dc.identifier.citation Ventura R, Matabosch X, Segura J. Bioanalytical techniques in discrimination between therapeutic and abusive use of drugs in sport. Bioanalysis. 2016 May;8(9):965-80. doi: 10.4155/bio.15.253ca
- dc.identifier.doi http://dx.doi.org/10.4155/bio.15.253
- dc.identifier.issn 1757-6180
- dc.identifier.uri http://hdl.handle.net/10230/26790
- dc.language.iso engca
- dc.publisher Future Scienceca
- dc.relation.ispartof Bioanalysis. 2016 May;8(9):965-80
- dc.rights This is the author's final version of the following article: Ventura R, Matabosch X, Segura J. Bioanalytical techniques in discrimination between therapeutic and abusive use of drugs in sport. Bioanalysis. 2016 May;8(9):965-80, which has been published in final form at http://dx.doi.org/10.4155/bio.15.253.ca
- dc.rights.accessRights info:eu-repo/semantics/openAccessca
- dc.subject.other Dopatge en els esportsca
- dc.subject.other Glucocorticoidesca
- dc.title Bioanalytical techniques in discrimination between therapeutic and abusive use of drugs in sportca
- dc.type info:eu-repo/semantics/articleca
- dc.type.version info:eu-repo/semantics/acceptedVersionca