Chromium in drinking water: association with biomarkers of exposure and effect

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• dc.contributor.author Sazakli, Eleni
• dc.contributor.author Villanueva, Cristina M.
• dc.contributor.author Kogevinas, Manolis
• dc.contributor.author Maltezis, Kyriakos
• dc.contributor.author Mouzaki, Athanasia
• dc.contributor.author Leotsinidis, Michalis
• dc.date.accessioned 2025-01-13T08:31:33Z
• dc.date.available 2025-01-13T08:31:33Z
• dc.date.issued 2014
• dc.description.abstract An epidemiological cross-sectional study was conducted in Greece to investigate health outcomes associated with long-term exposure to chromium via drinking water. The study population consisted of 304 participants. Socio-demographics, lifestyle, drinking water intake, dietary habits, occupational and medical history data were recorded through a personal interview. Physical examination and a motor test were carried out on the individuals. Total chromium concentrations were measured in blood and hair of the study subjects. Hematological, biochemical and inflammatory parameters were determined in blood. Chromium in drinking water ranged from <0.5 to 90 μg·L−1 in all samples but one (220 μg·L−1), with a median concentration of 21.2 μg·L−1. Chromium levels in blood (median 0.32 μg·L−1, range <0.18–0.92 μg·L−1) and hair (median 0.22 μg·g−1, range 0.03–1.26 μg·g−1) were found within “normal range” according to the literature. Personal lifetime chromium exposure dose via drinking water, calculated from the results of the water analyses and the questionnaire data, showed associations with blood and hair chromium levels and certain hematological and biochemical parameters. Groups of subjects whose hematological or biochemical parameters were outside the normal range were not correlated with chromium exposure dose, except for groups of subjects with high triglycerides or low sodium. Motor impairment score was not associated with exposure to chromium.en
• dc.format.mimetype application/pdf
• dc.identifier.citation Sazakli E, Villanueva C, Kogevinas M, Maltezis K, Mouzaki A, Leotsinidis M. Chromium in drinking water: association with biomarkers of exposure and effect. Int J Environ Res Public Health. 2014 Sep 29;11(10):10125-45. DOI: 10.3390/ijerph111010125
• dc.identifier.doi http://dx.doi.org/10.3390/ijerph111010125
• dc.identifier.issn 1660-4601
• dc.identifier.uri http://hdl.handle.net/10230/69056
• dc.language.iso eng
• dc.publisher MDPI
• dc.relation.ispartof International Journal of Environmental Research and Public Health. 2014 Sep 29;11(10):10125-45
• dc.rights © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Chromium oral consumptionen
• dc.subject.keyword Chromium hairen
• dc.subject.keyword Chromium blooden
• dc.subject.keyword Health effectsen
• dc.subject.keyword Epidemiological studyen
• dc.subject.keyword Biomarkers of exposure and effecten
• dc.title Chromium in drinking water: association with biomarkers of exposure and effect
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion