Salivary cotinine concentrations in daily smokers in Barcelona, Spain: a cross-sectional study.

Fu, Marcela; Fernández, Esteve; Martínez Sánchez, Jose María; Pascual, José A.; Schiaffino, Anna; Agudo Trigueros, Antonio; Ariza, Carles; Borràs, Josep M.; Samet, Jonathan M.

Salivary cotinine concentrations in daily smokers in Barcelona, Spain: a cross-sectional study.

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dc.contributor.author Fu, Marcelaca
dc.contributor.author Fernández, Esteveca
dc.contributor.author Martínez Sánchez, Jose Maríaca
dc.contributor.author Pascual, José A.ca
dc.contributor.author Schiaffino, Annaca
dc.contributor.author Agudo Trigueros, Antonioca
dc.contributor.author Ariza, Carlesca
dc.contributor.author Borràs, Josep M.ca
dc.contributor.author Samet, Jonathan M.ca
dc.date.accessioned 2014-12-22T12:59:46Z
dc.date.available 2014-12-22T12:59:46Z
dc.date.issued 2009ca
dc.description.abstract Background/nCharacterizing and comparing the determinant of cotinine concentrations in different populations should facilitate a better understanding of smoking patterns and addiction. This study describes and characterizes determinants of salivary cotinine concentration in a sample of Spanish adult daily smoker men and women. Methods: A cross-sectional study was carried out between March 2004 and December 2005 in a representative sample of 1245 people from the general population of Barcelona, Spain. A standard questionnaire was used to gather information on active tobacco smoking and passive exposure, and a saliva specimen was obtained to determine salivary cotinine concentration. Two hundred and eleven adult smokers (>16 years old) with complete data were included in the analysis. Determinants of cotinine concentrations were assessed using linear regression models. Results: Salivary cotinine concentration was associated with the reported number of cigarettes smoked in the previous 24 hours (R2 = 0.339; p < 0.05). The inclusion of a quadratic component for number of cigarettes smoked in the regression analyses resulted in an improvement of the fit (R2 = 0.386; p < 0.05). Cotinine concentration differed significantly by sex, with men having higher levels./nConclusion: This study shows that salivary cotinine concentration is significantly associated with the number of cigarettes smoked and sex, but not with other smoking-related variables.
dc.description.sponsorship This project was funded by the Instituto de Salud Carlos III (grants FIS PI020261 & PI081436) and the Thematic Network of Cooperative Research on Cancer (grant RD06/0020/0089), Government of Spain, and the Ministry of Universities and Research (grant 2009SGR192), Government of Catalonia. We also thank Chupa Chups Spain for providing the Smint® candies.
dc.format.mimetype application/pdfca
dc.identifier.citation Fu M, Fernandez E, Martínez-Sánchez JM, Pascual JA, Schiaffino A, Agudo A et al. Salivary cotinine concentrations in daily smokers in Barcelona, Spain: a cross-sectional study. BMC Public Health. 2009 Sep;9:320. DOI: 10.1186/1471-2458-9-320ca
dc.identifier.doi http://dx.doi.org/10.1186/1471-2458-9-320
dc.identifier.issn 1471-2458ca
dc.identifier.uri http://hdl.handle.net/10230/23024
dc.language.iso engca
dc.publisher BioMed Centralca
dc.relation.ispartof BMC Public Health. 2009 Sep;9:320
dc.rights.accessRights info:eu-repo/semantics/openAccessca
dc.subject.other Tabaquisme
dc.subject.other Fumadors
dc.subject.other Saliva
dc.subject.other Anàlisi
dc.title Salivary cotinine concentrations in daily smokers in Barcelona, Spain: a cross-sectional study.ca
dc.type info:eu-repo/semantics/articleca
dc.type.version info:eu-repo/semantics/publishedVersionca

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