Data on the endogenous conversion of tyrosol into hydroxytyrosol in humans
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- dc.contributor.author Boronat Rigol, Anna, 1990-
- dc.contributor.author Mateus Rodriguez, Julian Andrés
- dc.contributor.author Soldevila-Domenech, Natalia
- dc.contributor.author Guerra Albà, Mercè
- dc.contributor.author Rodríguez-Morató, Jose, 1987-
- dc.contributor.author Varon, Carlota
- dc.contributor.author Muñoz, Daniel
- dc.contributor.author Barbosa, Francina
- dc.contributor.author Morales, Juan Carlos
- dc.contributor.author Gaedigk, Andreas
- dc.contributor.author Langohr, Klaus
- dc.contributor.author Covas Planells, Maria Isabel
- dc.contributor.author Pérez Mañá, Clara
- dc.contributor.author Fitó Colomer, Montserrat
- dc.contributor.author Tyndale, Rachel F.
- dc.contributor.author Torre Fornell, Rafael de la
- dc.date.accessioned 2020-07-03T06:46:40Z
- dc.date.available 2020-07-03T06:46:40Z
- dc.date.issued 2019
- dc.description.abstract Here we present new and original data on the endogenous conversion of tyrosol (Tyr) into hydroxytyrosol (OHTyr) in humans and its effects on the cardiovascular system. A randomized, crossover, controlled clinical trial was performed with individuals at cardiovascular risk (n = 33). They received white wine (WW) (females 1, males 2 standard drinks/day), WW plus Tyr capsules (WW + Tyr) (25mg Tyr capsule, one per WW drink), and water (control) ad libitum. Intervention periods were of 4 weeks preceded by three-week wash-out periods. We assessed the conversion of Tyr to OHTyr, its interaction with a polygenic activity score (PAS) from CYP2A6 and CYP2D6 genotypes, and the effects on cardiovascular risk markers. For further details and experimental findings please refer to the article "Cardiovascular benefits of tyrosol and its endogenous conversion into hydroxytyrosol in humans. A randomized, controlled trial"
- dc.format.mimetype application/pdf
- dc.identifier.citation Boronat A, Mateus J, Soldevila-Domenech N, Guerra M, Rodríguez-Morató J, Varon C, Muñoz D, Barbosa F, Morales JC, Gaedigk A, Langohr K, Covas MI, Pérez-Mañá C, Fitó M, Tyndale RF, de la Torre R. Data on the endogenous conversion of tyrosol into hydroxytyrosol in humans. Data Brief. 2019; 27:104787. DOI: 10.1016/j.dib.2019.104787
- dc.identifier.doi http://dx.doi.org/10.1016/j.dib.2019.104787
- dc.identifier.issn 2352-3409
- dc.identifier.uri http://hdl.handle.net/10230/45063
- dc.language.iso eng
- dc.publisher Elsevier
- dc.relation.ispartof Data Brief. 2019; 27:104787
- dc.rights © 2019 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword CYP2A6
- dc.subject.keyword CYP2D6
- dc.subject.keyword Cardiovascular risk
- dc.subject.keyword Endogenous conversion
- dc.subject.keyword Hydroxytyrosol
- dc.subject.keyword Tyrosol
- dc.title Data on the endogenous conversion of tyrosol into hydroxytyrosol in humans
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion