Nutritional status and muscle dysfunction in chronic respiratory diseases: stable phase versus acute exacerbations
Mostra el registre complet Registre parcial de l'ítem
- dc.contributor.author Gea Guiral, Joaquim
- dc.contributor.author Sancho-Muñoz, Antoni
- dc.contributor.author Chalela Rengifo, Roberto José, 1985-
- dc.date.accessioned 2019-10-23T10:49:34Z
- dc.date.available 2019-10-23T10:49:34Z
- dc.date.issued 2018
- dc.description.abstract Nutritional abnormalities are frequent in different chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD), bronchiectasis, cystic fibrosis (CF), interstitial fibrosis and lung cancer, having important clinical consequences. However, nutritional abnormalities often remained underdiagnosed due to the relative lack of awareness of health professionals. Therefore, systematic anthropometry or even better, assessment of body composition, should be performed in all patients with chronic respiratory conditions, especially following exacerbation periods when malnutrition becomes more accentuated. Nutritional abnormalities very often include the loss of muscle mass, which is an important factor for the occurrence of muscle dysfunction. The latter can be easily detected with the specific assessment of muscle strength and endurance, and also negatively influences patients' quality of life and prognosis. Both nutritional abnormalities and muscle dysfunction result from the interaction of several factors, including tobacco smoking, low physical activity-sedentarism, systemic inflammation and the imbalance between energy supply and requirements, which essentially lead to a negative balance between protein breakdown and synthesis. Therapeutic approaches include improvements in lifestyle, nutritional supplementation and training. Anabolic drugs may be administered in some cases.
- dc.format.mimetype application/pdf
- dc.identifier.citation Gea J, Sancho-Muñoz A, Chalela R. Nutritional status and muscle dysfunction in chronic respiratory diseases: stable phase versus acute exacerbations. J Thorac Dis. 2018;10(Suppl 12):1332-54. DOI: 10.21037/jtd.2018.02.66
- dc.identifier.doi http://dx.doi.org/10.21037/jtd.2018.02.66
- dc.identifier.issn 2072-1439
- dc.identifier.uri http://hdl.handle.net/10230/42492
- dc.language.iso eng
- dc.publisher Pioneer Bioscience Pub. Co.
- dc.relation.ispartof Journal of Thoracic Disease. 2018;10(Suppl 12):1332-54
- dc.rights © Journal of Thoracic Disease. All rights reserved.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.subject.keyword Nutritional abnormalities
- dc.subject.keyword Diet
- dc.subject.keyword Exercise
- dc.subject.keyword Low body weight
- dc.subject.keyword Lung diseases
- dc.subject.keyword Muscle dysfunction
- dc.subject.keyword Muscle mass
- dc.subject.keyword Prognosis
- dc.title Nutritional status and muscle dysfunction in chronic respiratory diseases: stable phase versus acute exacerbations
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/acceptedVersion