Successful treatment of hypertrophic herpes simplex genitalis in HIV-infected patient with topical imiquimod.

Deza Vargas, Luis Gustavo; Martin-Ezquerra, Gemma; Curto Barredo, Laia; Villar García, Judit; Pujol Vallverdú, Ramon Maria

doi:http://dx.doi.org/10.1111/1346-8138.12969

Successful treatment of hypertrophic herpes simplex genitalis in HIV-infected patient with topical imiquimod.

Citation

Deza G, Martin-Ezquerra G, Curto-Barredo L, Villar García J, Pujol RM. Successful treatment of hypertrophic herpes simplex genitalis in HIV-infected patient with topical imiquimod. J Dermatol. 2015 Dec;42(12):1176-8. doi: 10.1111/1346-8138.12969.

Abstract

Hypertrophic herpes simplex genitalis is an atypical presentation of genital herpes described in the context of immunosuppression, particularly HIV-positive patients. This situation can become a diagnostic and therapeutic challenge. For this reason, alternative therapies are currently being discussed in the literature. We report a case of hypertrophic genital herpes in a HIV-positive patient who was successfully treated with topical 5% imiquimod after treatment failures with oral and i.v. antivirals.