Feasibility and tolerability of bone impact microindentation testing: a cross-sectional, population-based study in Australia
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- dc.contributor.author Rufus-Membere, Pamela
- dc.contributor.author Holloway-Kew, Kara L.
- dc.contributor.author Diez-Perez, Adolfo
- dc.contributor.author Kotowicz, Mark A.
- dc.contributor.author Pasco, Julie A.
- dc.date.accessioned 2019-03-18T08:37:02Z
- dc.date.available 2019-03-18T08:37:02Z
- dc.date.issued 2018
- dc.description.abstract OBJECTIVES: The OsteoProbe measures Bone Material Strength Index (BMSi) of cortical bone in living humans using impact microindentation (IMI). Research using this minimally invasive technique is expanding yet, to-date, there have been no reports about its feasibility in the research setting. In this study, we assessed the feasibility and tolerability of using the OsteoProbe in men enrolled in the Geelong Osteoporosis Study. DESIGN: Cross-sectional analysis of data collected in a population-based study. SETTING: Barwon Statistical Division, southeastern Australia, 2016-2018. METHODS: For 252 of 345 consecutive participants (ages 33-96 years), BMSi was measured using the OsteoProbe at the mid-tibia. Immediately following measurement, each participant used a Visual Analogue Scale (0-10) to rate the level of discomfort that was anticipated and experienced, their initial reluctance towards the measurement and their willingness to repeat measurement. RESULTS: Reasons for non-measurement in 92 men were needle phobia (n=8), discomfort after first indentation (n=5), skin infections (n=21), excessive soft tissues around the mid-tibia region (n=56), inability to provide informed consent (n=2). Among 252 men who had IMI measures, the expectation for pain during measurement was low (1.54±1.56), as was actual pain experienced (0.38±0.71). Reluctance to undergo measurement was low (0.34±0.93). All participants indicated a willingness to have the measurement performed again. Mean (±SD) BMSi was 83.0±6.4 (range 62.3-93.0). CONCLUSION: In this study, the procedure was well accepted by participants suggesting that IMI testing with the OsteoProbe is feasible in a research setting.
- dc.format.mimetype application/pdf
- dc.identifier.citation Rufus-Membere P, Holloway-Kew KL, Diez-Perez A, Kotowicz MA, Pasco JA. Feasibility and tolerability of bone impact microindentation testing: a cross-sectional, population-based study in Australia. BMJ Open. 2018 Dec 22;8(12):e023959. DOI: 10.1136/bmjopen-2018-023959
- dc.identifier.doi http://dx.doi.org/10.1136/bmjopen-2018-023959
- dc.identifier.issn 2044-6055
- dc.identifier.uri http://hdl.handle.net/10230/36847
- dc.language.iso eng
- dc.publisher BMJ Publishing Group
- dc.relation.ispartof BMJ Open. 2018 Dec 22;8(12):e023959
- dc.rights This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
- dc.subject.keyword OsteoProbe
- dc.subject.keyword Bone material strength index
- dc.subject.keyword Fractures
- dc.subject.keyword Microidentation
- dc.subject.other Fractures
- dc.subject.other Ossos -- Anàlisi
- dc.title Feasibility and tolerability of bone impact microindentation testing: a cross-sectional, population-based study in Australia
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion