Staphylococcus aureus surgical site infection rates in 5 European countries

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• dc.contributor.author Mellinghoff, Sibylle C.
• dc.contributor.author Fernández Ferrer, Maria
• dc.contributor.author Horcajada Gallego, Juan Pablo
• dc.contributor.author Liss, Blasius J.
• dc.date.accessioned 2024-03-12T16:00:01Z
• dc.date.available 2024-03-12T16:00:01Z
• dc.date.issued 2023
• dc.description.abstract Objective: To determine the overall and procedure-specific incidence of surgical site infections (SSI) caused by Staphylococcus aureus (S. aureus) as well as risk factors for such across all surgical disciplines in Europe. Methods: This is a retrospective cohort of patients with surgical procedures performed at 14 European centres in 2016, with a nested case-control analysis. S. aureus SSI were identified by a semi-automated crossmatching bacteriological and electronic health record data. Within each surgical procedure, cases and controls were matched using optimal propensity score matching. Results: A total of 764 of 178 902 patients had S. aureus SSI (0.4%), with 86.0% of these caused by methicillin susceptible and 14% by resistant pathogens. Mean S. aureus SSI incidence was similar for all surgical specialties, while varying by procedure. Conclusions: This large procedure-independent study of S. aureus SSI proves a low overall infection rate of 0.4% in this cohort. It provides proof of principle for a semi-automated approach to utilize big data in epidemiological studies of healthcare-associated infections. Trials registration The study was registered at clinicaltrials.gov under NCT03353532 (11/2017).
• dc.format.mimetype application/pdf
• dc.identifier.citation Mellinghoff SC, Bruns C, Albertsmeier M, Ankert J, Bernard L, Budin S et al. Staphylococcus aureus surgical site infection rates in 5 European countries. Antimicrob Resist Infect Control. 2023 Sep 19;12(1):104. DOI: 10.1186/s13756-023-01309-w
• dc.identifier.doi http://dx.doi.org/10.1186/s13756-023-01309-w
• dc.identifier.issn 2047-2994
• dc.identifier.uri http://hdl.handle.net/10230/59388
• dc.language.iso eng
• dc.publisher BioMed Central
• dc.relation.ispartof Antimicrob Resist Infect Control. 2023 Sep 19;12(1):104
• dc.rights © The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Hospital acquired infection
• dc.subject.keyword Staphylococcus aureus
• dc.subject.keyword Surgical site infection
• dc.title Staphylococcus aureus surgical site infection rates in 5 European countries
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion