Characteristics of patients admitted for the first time for COPD exacerbation

Balcells Vilarnau, Eva, 1967-; Antó i Boqué, Josep Maria; Gea Guiral, Joaquim; Gómez, Federico P.; Rodríguez, Esther; Marin, Alicia; Ferrer, Antoni-Lluc, 1942-; De Batlle, Jordi; Farrero, Eva; Benet, Marta; Orozco Levi, Mauricio; Ferrer, Jaume; Agustí García-Navarro, Àlvar; Gáldiz, Juan B.; Belda, José; García Aymerich, Judith

Characteristics of patients admitted for the first time for COPD exacerbation

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dc.contributor.author Balcells Vilarnau, Eva, 1967-ca
dc.contributor.author Antó i Boqué, Josep Mariaca
dc.contributor.author Gea Guiral, Joaquimca
dc.contributor.author Gómez, Federico P.ca
dc.contributor.author Rodríguez, Estherca
dc.contributor.author Marin, Aliciaca
dc.contributor.author Ferrer, Antoni-Lluc, 1942-ca
dc.contributor.author De Batlle, Jordica
dc.contributor.author Farrero, Evaca
dc.contributor.author Benet, Martaca
dc.contributor.author Orozco Levi, Mauricioca
dc.contributor.author Ferrer, Jaumeca
dc.contributor.author Agustí García-Navarro, Àlvarca
dc.contributor.author Gáldiz, Juan B.ca
dc.contributor.author Belda, Joséca
dc.contributor.author García Aymerich, Judithca
dc.date.accessioned 2017-11-02T11:01:18Z
dc.date.available 2017-11-02T11:01:18Z
dc.date.issued 2009
dc.description.abstract BACKGROUND: This study describes the characteristics of a large sample of patients hospitalised for the first time for a chronic obstructive pulmonary disease (COPD) exacerbation. METHODS: All subjects first admitted for a COPD exacerbation to nine teaching Spanish hospitals during January 2004-March 2006, were eligible. COPD diagnosis was confirmed by spirometry under stability. At admission, sociodemographic data, lifestyle, previous treatment and diagnosis of respiratory disease, lung function and Charlson index of co-morbidity were collected. A comprehensive assessment, including dyspnea, lung function, six-minute walking test, and St. George's Respiratory Questionnaire (SGRQ), was completed 3 months after admission, during a clinically stable disease period. RESULTS: Three-hundred and forty-two patients (57% of the eligible) participated in the study: 93% males, mean (SD) age 68 (9) years, 42% current smokers, 50% two or more co-morbidities, 54% mild-to-moderate dyspnea, post-bronchodilator FEV(1) 52 (16)% of predicted (54% mild-to-moderate COPD in ATS/ERS stages), 6-min walking distance 440 m, total SGRQ score 37 (18), and 36% not report respiratory disease. The absence of a previous COPD diagnosis, positive bronchodilator test, female gender, older age, higher DLco and higher BMI were independently associated with less severe COPD. CONCLUSIONS: We show that the patients admitted after presenting with their first COPD exacerbation have a wide range of severity, with a large proportion of patients in the less advanced COPD stages.
dc.description.sponsorship The PAC-COPD study is funded by grants from Fondo de Investigación Sanitaria (FIS PI020541), Ministry of Health, Spain; Agència d’Avaluació de Tecnologia i Recerca Mèdiques (AATRM 035/20/02), Catalonia Government; Spanish Society of Pneumology and Thoracic Surgery (SEPAR 2002/137); Catalan Foundation of Pneumology (FUCAP 2003 Beca Marià Ravà); Red RESPIRA (RTIC C03/11); Red RCESP (RTICC03/09); Fondo de Investigación Sanitaria (PI052486); Fondo de Investigación Sanitaria (PI052302); Fundació La Marató de TV3 (num. 041110); Novartis Farmacèutica, Spain. CIBERESP and CIBERES are funded by the Instituto de Salud Carlos III, Ministry of Health, Spain. Judith Garcia Aymerich has a researcher contract from the Instituto de Salud Carlos III (CP05/00118), Ministry of Health, Spain. Jordi de Batlle had a predoctoral fellowship from the Instituto de Salud Carlos III (FI05/01022), Ministry of Health, Spain.
dc.format.mimetype application/pdfca
dc.identifier.citation Balcells E, Antó JM, Gea J, Gómez FP, Rodríguez E, Marin A et al. Characteristics of patients admitted for the first time for COPD exacerbation. Respir Med. 2009 Sep;103(9):1293-302. DOI: 10.1016/j.rmed.2009.04.001
dc.identifier.doi http://dx.doi.org/10.1016/j.rmed.2009.04.001
dc.identifier.issn 0954-6111
dc.identifier.uri http://hdl.handle.net/10230/33125
dc.language.iso eng
dc.publisher Elsevierca
dc.relation.ispartof Respiratory Medicine. 2009 Sep;103(9):1293-302
dc.rights © Elsevier This is the published version of an article http://dx.doi.org/10.1016/j.rmed.2009.04.001 that appeared in the journal Respiratory Medicine. It is published in an Open Archive under an Elsevier user license. Details of this licence are available here: http://www.elsevier.com/about/open-access/open-access-policies/oa-license-policy/elsevier-user-license
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.subject.other Assistència hospitalària
dc.subject.other Pulmons -- Malalties obstructives
dc.title Characteristics of patients admitted for the first time for COPD exacerbationca
dc.type info:eu-repo/semantics/article
dc.type.version info:eu-repo/semantics/publishedVersion

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