Persistent cutaneous abdominal ulcerations secondary to diffuse dermal angiomatosis: an underestimated sign for severe atherosclerosis: A case report.

García-Colmenero, Lidia; Martin-Ezquerra, Gemma; Gómez-Martín, Ignacio; Mellado Joan, Meritxell; Barranco Sanz, Luis Carlos; Albero-González, Raquel; Villar García, Judit; Pujol Vallverdú, Ramon Maria

Persistent cutaneous abdominal ulcerations secondary to diffuse dermal angiomatosis: an underestimated sign for severe atherosclerosis: A case report.

Mostra el registre complet Registre parcial de l'ítem

dc.contributor.author García-Colmenero, Lidiaca
dc.contributor.author Martin-Ezquerra, Gemmaca
dc.contributor.author Gómez-Martín, Ignacioca
dc.contributor.author Mellado Joan, Meritxellca
dc.contributor.author Barranco Sanz, Luis Carlosca
dc.contributor.author Albero-González, Raquelca
dc.contributor.author Villar García, Juditca
dc.contributor.author Pujol Vallverdú, Ramon Mariaca
dc.date.accessioned 2017-01-10T11:22:04Z
dc.date.available 2017-01-10T11:22:04Z
dc.date.issued 2016
dc.description.abstract BACKGROUND: Diffuse dermal angiomatosis (DDA) is a rare, acquired, reactive vascular proliferation, clinically characterized by livedoid erythematous-violaceous plaques, which frequently evolve to ulceration and necrosis. Histopathologically, it is manifested by a diffuse proliferation of endothelial cells within the full thickness of the dermis. DDA has been mainly associated with severe peripheral atherosclerosis. METHODS: We report a 63-year-old woman who presented with multiple erythematous-violaceous plaques with central deep skin ulcers on thighs, lower abdomen, and perianal area, associated with intermittent claudication, low-grade fever, and weight loss. Initially, the clinical picture along with positive cultures for Klebsiella pneumoniae suggested a multifocal ecthyma gangrenosum; nevertheless, a skin biopsy showed a diffuse dermal proliferation of endothelial cells interstitially arranged between collagen bundles. A computed tomography scan revealed severe aortic atheromatosis with complete luminal occlusion of the infrarenal aorta and common iliac arteries. RESULTS: The diagnosis of DDA secondary to severe atherosclerosis was established. The patient underwent a left axillofemoral bypass surgery with a rapidly healing of the ulcers in the next weeks./nCONCLUSIONS: DDA should be considered in the differential diagnosis of livedoid ischemic lesions. Recognition of DDA as a cutaneous sign of severe peripheral vascular disease is important for both dermatologists and internists. Recognition of risk factors and their management with an early intervention to correct tissue ischemia can be curative.ca
dc.format.mimetype application/pdfca
dc.identifier.citation García-Colmenero L, Martin-Ezquerra G, Gómez-Martín I, Mellado Joan M, Barranco C, Albero-González R. et al. Persistent cutaneous abdominal ulcerations secondary to diffuse dermal angiomatosis: an underestimated sign for severe atherosclerosis: A case report. Medicine (Baltimore). 2016 Jul;95(29):e4212. doi: 10.1097/MD.0000000000004212ca
dc.identifier.doi http://dx.doi.org/10.1097/MD.0000000000004212
dc.identifier.issn 0025-7974
dc.identifier.uri http://hdl.handle.net/10230/27863
dc.language.iso engca
dc.publisher Wolters Kluwer Open Healthca
dc.relation.ispartof Medicine (Baltimore). 2016 Jul;95(29):e4212
dc.rights.accessRights info:eu-repo/semantics/openAccessca
dc.subject.other Aterosclerosica
dc.subject.other Úlceresca
dc.title Persistent cutaneous abdominal ulcerations secondary to diffuse dermal angiomatosis: an underestimated sign for severe atherosclerosis: A case report.ca
dc.type info:eu-repo/semantics/articleca
dc.type.version info:eu-repo/semantics/publishedVersionca

Col·leccions

Articles (Hospital del Mar Research Institute)