Restrictive spirometry pattern is associated with low physical activity levels. A population based international study

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  • dc.contributor.author Carsin, Anne-Elie
  • dc.contributor.author Fuertes, Elaine
  • dc.contributor.author Antó i Boqué, Josep Maria
  • dc.contributor.author Guerra, Stefano
  • dc.contributor.author García Aymerich, Judith
  • dc.date.accessioned 2019-07-31T06:11:48Z
  • dc.date.available 2019-07-31T06:11:48Z
  • dc.date.issued 2019
  • dc.description.abstract Introduction: Restrictive spirometry pattern is an under-recognised disorder with a poor morbidity and mortality prognosis. We compared physical activity levels between adults with a restrictive spirometry pattern and with normal spirometry. Methods: Restrictive spirometry pattern was defined as a having post-bronchodilator FEV1/FVC ≥ Lower Limit of Normal and a FVC<80% predicted in two population-based studies (ECRHS-III and SAPALDIA3). Physical activity was measured using the International Physical Activity Questionnaire. The odds of having low physical activity (<1st study-specific tertile) was evaluated using adjusted logistic regression models. Results: Subjects with a restrictive spirometry pattern (n = 280/4721 in ECRHS, n = 143/3570 in SAPALDIA) reported lower levels of physical activity than those with normal spirometry (median of 1770 vs 2253 MET·min/week in ECRHS, and 3519 vs 3945 MET·min/week in SAPALDIA). Subjects with a restrictive spirometry pattern were more likely to report low physical activity (meta-analysis odds ratio: 1.41 [95%CI 1.07–1.86]) than those with a normal spirometry. Obesity, respiratory symptoms, co-morbidities and previous physical activity levels did not fully explain this finding. Conclusion: Adults with a restrictive spirometry pattern were more likely to report low levels of physical activity than those with normal spirometry. These results highlight the need to identify and act on this understudied but prevalent condition.
  • dc.description.sponsorship The present analyses are part of the Ageing Lungs in European Cohorts (ALEC) Study (www.alecstudy.org), which has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No. 633212. The local investigators and funding agencies for the European Community Respiratory Health Survey (ECRHS II and ECRHS III) are reported in the Supplementary Material. SAPALDIA is funded by the National Science Foundation Grant Nr. 33CS30-177506. Elaine Fuertes was funded from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Individual Fellowship scheme (H2020-MSCA-IF-2015; proposal number 704268). ISGlobal is a member of CERCA Programme/Generalitat de Catalunya.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Carsin AE, Fuertes E, Schaffner E, Jarvis D, Antó JM, Heinrich J et al. Restrictive spirometry pattern is associated with low physical activity levels. A population based international study. Respir Med. 2019;146:116-23. DOI: 10.1016/j.rmed.2018.11.017
  • dc.identifier.doi http://dx.doi.org/10.1016/j.rmed.2018.11.017
  • dc.identifier.issn 0954-6111
  • dc.identifier.uri http://hdl.handle.net/10230/42210
  • dc.language.iso eng
  • dc.publisher Elsevier
  • dc.relation.ispartof Respiratory Medicine. 2019;146:116-23
  • dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/633212
  • dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/704268
  • dc.rights © 2019 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/).
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/
  • dc.subject.keyword Restrictive spirometry pattern
  • dc.subject.keyword Body mass index
  • dc.subject.keyword Epidemiology
  • dc.subject.keyword Lung function
  • dc.subject.keyword Physical activity
  • dc.title Restrictive spirometry pattern is associated with low physical activity levels. A population based international study
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion

Col·leccions

Articles (Departament de Medicina i Ciències de la Vida)
Articles (Barcelona Institute for Global Health (ISGlobal) – Campus Mar)
Articles (Hospital del Mar Research Institute)
Documents OpenAIRE (Open Access Infrastructure for Research in Europe)