Epidemiology of sepsis in Catalonia: analysis of incidence and outcomes in a European setting
Mostra el registre complet Registre parcial de l'ítem
- dc.contributor.author Yébenes, Juan Carlos
- dc.contributor.author Ruiz-Rodriguez, Juan C.
- dc.contributor.author Ferrer, Ricard
- dc.contributor.author Clèries, Montse
- dc.contributor.author Bosch, Anna
- dc.contributor.author Lorencio, Carol
- dc.contributor.author Rodriguez, Alejandro
- dc.contributor.author Nuvials Casals, Xavier
- dc.contributor.author Martin-Loeches, Ignacio
- dc.contributor.author Artigas, Antoni
- dc.contributor.author SOCMIC (Catalonian Critical Care Society) Sepsis Working Group
- dc.date.accessioned 2025-02-03T07:46:57Z
- dc.date.available 2025-02-03T07:46:57Z
- dc.date.issued 2017
- dc.description Includes supplementary materials for the online appendix.
- dc.description.abstract Background. Up-to-date identification of local trends in sepsis incidence and outcomes is of considerable public health importance. The aim of our study was to estimate annual incidence rates and in-hospital mortality trends for hospitalized patients with sepsis in a European setting, while avoiding selection bias in relation to different complexity hospitals. Methods. A large retrospective analysis of a 5-year period (2008–2012) was conducted of hospital discharge records obtained from the Catalan Health System (CatSalut) Minimum Basic Data Set for Acute-Care Hospitals (a mandatory population-based register of admissions to all public and private acute-care hospitals in Catalonia). Patients hospitalized with sepsis were detected on the basis of ICD-9-CM codes used to identify acute organ dysfunction and infectious processes. Results. Of 4,761,726 discharges from all acute-care hospitals in Catalonia, 82,300 cases (1.72%) had sepsis diagnoses. Annual incidence was 212.7 per 100,000 inhabitants/year, rising from 167.2 in 2008 to 261.8 in 2012. Length of hospital stay fell from 18.4 to 15.3 days (p < .00001), representing a relative reduction of 17%. Hospital mortality fell from 23.7 to 19.7% (p < .0001), representing a relative reduction of 16.9%. These differences were confirmed in the multivariate analysis (adjusted for age group, sex, comorbidities, ICU admission, emergency admission, organ dysfunction, number of organ failures, sepsis source and bacteraemia). Conclusions. Sepsis incidence has risen in recent years, whereas mortality has fallen. Our findings confirm reports for other parts of the world, in the context of scarce administrative data on sepsis in Europe.en
- dc.format.mimetype application/pdf
- dc.identifier.citation Yébenes JC, Ruiz-Rodriguez JC, Ferrer R, Clèries M, Bosch A, Lorencio C, et al. Epidemiology of sepsis in Catalonia: analysis of incidence and outcomes in a European setting. Ann Intensive Care. 2017 Dec;7(1):19. DOI: 10.1186/s13613-017-0241-1
- dc.identifier.doi http://dx.doi.org/10.1186/s13613-017-0241-1
- dc.identifier.issn 2110-5820
- dc.identifier.uri http://hdl.handle.net/10230/69440
- dc.language.iso eng
- dc.publisher Springer
- dc.relation.ispartof Annals of Intensive Care. 2017 Dec;7(1):19
- dc.relation.isreferencedby http://dx.doi.org/10.6084/m9.figshare.c.3696145_D1.v1
- dc.rights This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Sepsisen
- dc.subject.keyword Septic shocken
- dc.subject.keyword Mortalityen
- dc.subject.keyword Epidemiologyen
- dc.title Epidemiology of sepsis in Catalonia: analysis of incidence and outcomes in a European settingen
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion