Weight loss and quality of life in patients surviving 2 years after gastric cancer resection

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  • dc.contributor.author Climent Agustín, Marta Carmenca
  • dc.contributor.author Munarriz, Marinaca
  • dc.contributor.author Blazeby, Jane M.ca
  • dc.contributor.author Dorcaratto, Dimitrica
  • dc.contributor.author Ramón Moros, José Manuelca
  • dc.contributor.author Carrera Santaliestra, M. Joséca
  • dc.contributor.author Fontane Francia, Laiaca
  • dc.contributor.author Grande Posa, Luísca
  • dc.contributor.author Pera Roman, Manuel Ramónca
  • dc.date.accessioned 2018-01-10T08:24:50Z
  • dc.date.issued 2017
  • dc.description.abstract BACKGROUND: Malnutrition is common in patients undergoing gastric cancer resection, leading to weight loss, although little is known about how this impacts on health-related quality of life (HRQL). This study aimed to explore the association between HRQL and weight loss in patients 2 years after curative gastric cancer resection. METHODS: Consecutive patients undergoing curative gastric cancer resection and surviving at least 2 years without disease recurrence were recruited. Patients completed the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and the specific module for gastric cancer (STO22) before and 2 years postoperatively and associations between HRQL scores and patients with and without ≥ 10% body weight loss (BWL) were examined. RESULTS: A total of 76 patients were included, of whom 51 (67%) had BWL ≥10%. At 2 years postoperatively, BWL ≥10% was associated with deterioration of all functional aspects of quality of life, with persistent pain (21.6%), diarrhoea (13.7%) and nausea/vomiting (13.7%). By contrast, none of the patients with BWL <10% experienced severe nausea/vomiting, pain or diarrhoea. CONCLUSIONS: Disabling symptoms occurred more frequently in patients with ≥10% BWL than in those with <10% BWL, with a relevant negative impact on HRQL. A cause-effect relationship between weight loss and postoperative outcome remains unsolved.
  • dc.format.mimetype application/pdfca
  • dc.identifier.citation Climent M, Munarriz M, Blazeby JM, Dorcaratto D, Ramón JM, Carrera MJ. Et al. Weight loss and quality of life in patients surviving 2 years after gastric cancer resection. Eur J Surg Oncol. 2017 Jul;43(7):1337-1343. DOI: 10.1016/j.ejso.2017.01.239
  • dc.identifier.doi http://dx.doi.org/10.1016/j.ejso.2017.01.239
  • dc.identifier.issn 0748-7983
  • dc.identifier.uri http://hdl.handle.net/10230/33607
  • dc.language.iso eng
  • dc.publisher Elsevierca
  • dc.relation.ispartof European Journal of Surgical Oncology. 2017 Jul;43(7):1337-43
  • dc.rights © Elsevier http://dx.doi.org/10.1016/j.ejso.2017.01.239
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.subject.keyword Gastric cancer
  • dc.subject.keyword Quality of life
  • dc.subject.keyword Surgery
  • dc.subject.keyword Weight loss
  • dc.subject.other Aparell digestiu -- Càncer
  • dc.subject.other Estómac -- Càncer
  • dc.subject.other Qualitat de vida
  • dc.title Weight loss and quality of life in patients surviving 2 years after gastric cancer resectionca
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/acceptedVersion