Evaluation of a lung ultrasound score in hospitalized adult patients with COVID-19 in Barcelona, Spain
Mostra el registre complet Registre parcial de l'ítem
- dc.contributor.author Lightowler, Maria S.
- dc.contributor.author Sander, Julia Verena
- dc.contributor.author García de Casasola Sánchez, Gonzalo
- dc.contributor.author Mateos González, Maria
- dc.contributor.author Güerri Fernández, Roberto
- dc.contributor.author Lorenzo Navarro, Maria Dolores
- dc.contributor.author Nackers, Fabienne
- dc.contributor.author Stratta, Erin
- dc.contributor.author Lanusse, Candelaria
- dc.contributor.author Huerga, Helena
- dc.date.accessioned 2025-06-06T07:04:28Z
- dc.date.available 2025-06-06T07:04:28Z
- dc.date.issued 2024
- dc.description.abstract Background/Objectives: During the COVID-19 pandemic and the burden on hospital resources, the rapid categorization of high-risk COVID-19 patients became essential, and lung ultrasound (LUS) emerged as an alternative to chest computed tomography, offering speed, non-ionizing, repeatable, and bedside assessments. Various LUS score systems have been used, yet there is no consensus on an optimal severity cut-off. We assessed the performance of a 12-zone LUS score to identify adult COVID-19 patients with severe lung involvement using oxygen saturation (SpO2)/fractional inspired oxygen (FiO2) ratio as a reference standard to define the best cut-off for predicting adverse outcomes. Methods: We conducted a single-centre prospective study (August 2020-April 2021) at Hospital del Mar, Barcelona, Spain. Upon admission to the general ward or intensive care unit (ICU), clinicians performed LUS in adult patients with confirmed COVID-19 pneumonia. Severe lung involvement was defined as a SpO2/FiO2 ratio <315. The LUS score ranged from 0 to 36 based on the aeration patterns. Results: 248 patients were included. The admission LUS score showed moderate performance in identifying a SpO2/FiO2 ratio <315 (area under the ROC curve: 0.71; 95%CI 0.64-0.77). After adjustment for COVID-19 risk factors, an admission LUS score ≥17 was associated with an increased risk of in-hospital death (OR 5.31; 95%CI: 1.38-20.4), ICU admission (OR 3.50; 95%CI: 1.37-8.94) and need for IMV (OR 3.31; 95%CI: 1.19-9.13). Conclusions: Although the admission LUS score had limited performance in identifying severe lung involvement, a cut-off ≥17 score was associated with an increased risk of adverse outcomes. and could play a role in the rapid categorization of COVID-19 pneumonia patients, anticipating the need for advanced care.
- dc.format.mimetype application/pdf
- dc.identifier.citation Lightowler MS, Sander JV, García de Casasola Sánchez G, Mateos González M, Güerri-Fernández R, Lorenzo Navarro MD, et al. Evaluation of a lung ultrasound score in hospitalized adult patients with COVID-19 in Barcelona, Spain. J Clin Med. 2024 Jun 2;13(11):3282. DOI: 10.3390/jcm13113282
- dc.identifier.doi http://dx.doi.org/10.3390/jcm13113282
- dc.identifier.issn 2077-0383
- dc.identifier.uri http://hdl.handle.net/10230/70631
- dc.language.iso eng
- dc.publisher MDPI
- dc.relation.ispartof J Clin Med. 2024 Jun 2;13(11):3282
- dc.rights © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword COVID-19
- dc.subject.keyword SARS-CoV-2
- dc.subject.keyword SpO2/FiO2 ratio
- dc.subject.keyword Clinical outcome
- dc.subject.keyword Lung ultrasound
- dc.subject.keyword Scoring system
- dc.title Evaluation of a lung ultrasound score in hospitalized adult patients with COVID-19 in Barcelona, Spain
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion