A compendium answering 150 questions on COVID-19 and SARS-CoV-2

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  • dc.contributor.author Riggioni, Carmen
  • dc.contributor.author Antó i Boqué, Josep Maria
  • dc.contributor.author Akdis, Cezmi A.
  • dc.date.accessioned 2020-12-21T07:52:59Z
  • dc.date.issued 2020
  • dc.description.abstract In December 2019, China reported the first cases of the coronavirus disease 2019 (COVID-19). This disease, caused by the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), has developed into a pandemic. To date, it has resulted in ~9 million confirmed cases and caused almost 500 000 related deaths worldwide. Unequivocally, the COVID-19 pandemic is the gravest health and socioeconomic crisis of our time. In this context, numerous questions have emerged in demand of basic scientific information and evidence-based medical advice on SARS-CoV-2 and COVID-19. Although the majority of the patients show a very mild, self-limiting viral respiratory disease, many clinical manifestations in severe patients are unique to COVID-19, such as severe lymphopenia and eosinopenia, extensive pneumonia, a "cytokine storm" leading to acute respiratory distress syndrome, endothelitis, thromboembolic complications, and multiorgan failure. The epidemiologic features of COVID-19 are distinctive and have changed throughout the pandemic. Vaccine and drug development studies and clinical trials are rapidly growing at an unprecedented speed. However, basic and clinical research on COVID-19-related topics should be based on more coordinated high-quality studies. This paper answers pressing questions, formulated by young clinicians and scientists, on SARS-CoV-2, COVID-19, and allergy, focusing on the following topics: virology, immunology, diagnosis, management of patients with allergic disease and asthma, treatment, clinical trials, drug discovery, vaccine development, and epidemiology. A total of 150 questions were answered by experts in the field providing a comprehensive and practical overview of COVID-19 and allergic disease.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Riggioni C, Comberiati P, Giovannini M, Agache I, Akdis M, Alves-Correia M et al. A compendium answering 150 questions on COVID-19 and SARS-CoV-2. Allergy. 2020 Oct;75(10):2503-41. DOI: 10.1111/all.14449
  • dc.identifier.doi http://dx.doi.org/10.1111/all.14449
  • dc.identifier.issn 0105-4538
  • dc.identifier.uri http://hdl.handle.net/10230/46097
  • dc.language.iso eng
  • dc.publisher Wiley
  • dc.relation.ispartof Allergy. 2020 Oct;75(10):2503-41
  • dc.rights This is the peer reviewed version of the following article: Riggioni C, Comberiati P, Giovannini M, Agache I, Akdis M, Alves-Correia M et al. A compendium answering 150 questions on COVID-19 and SARS-CoV-2. Allergy. 2020 Oct;75(10):2503-41, which has been published in final form at http://dx.doi.org/10.1111/all.14449. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.subject.keyword COVID-19
  • dc.subject.keyword SARS-CoV-2
  • dc.subject.keyword Allergy
  • dc.subject.keyword Coronavirus disease 2019
  • dc.subject.keyword Severe acute respiratory syndrome-related coronavirus 2
  • dc.title A compendium answering 150 questions on COVID-19 and SARS-CoV-2
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/acceptedVersion

Col·leccions

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