Short-term outcomes by chronic betablocker treatment in patients presenting to emergency departments with acute heart failure: BB-EAHFE

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  • dc.contributor.author Jacob, Javier
  • dc.contributor.author Haro, Antoni
  • dc.contributor.author Tost, Josep
  • dc.contributor.author Rosselló, Xavier
  • dc.contributor.author Llorens, Pere
  • dc.contributor.author Herrero-Puente, Pablo
  • dc.contributor.author Martín-Sánchez, Francisco J.
  • dc.contributor.author Gil, Víctor
  • dc.contributor.author López-Grima, María Luisa
  • dc.contributor.author Millán, Javier
  • dc.contributor.author Aguirre Tejedo, Alfons
  • dc.contributor.author Garrido, José Manuel
  • dc.contributor.author Calvo-Rodríguez, Rafael
  • dc.contributor.author Pérez-Llantada, Enrique
  • dc.contributor.author Sánchez-Nicolás, José Andrés
  • dc.contributor.author Mir, María
  • dc.contributor.author Rodríguez-Adrada, Esther
  • dc.contributor.author Fuentes-De Frutos, Marta
  • dc.contributor.author Roset, Alex
  • dc.contributor.author Miró, Òscar
  • dc.date.accessioned 2023-02-03T07:58:16Z
  • dc.date.issued 2022
  • dc.description.abstract Aims: to evaluate the association between chronic treatment with betablockers (BB) and the severity of decompensation and short-term outcomes of patients with acute heart failure (AHF). Methods and results: we consecutively included all patients presenting with AHF to 45 Spanish emergency departments (ED) during six different time-periods between 2007 and 2018. Patients were stratified according to whether they were on chronic treatment with BB at the time of ED consultation. Those receiving BB were compared (adjusted odds ratio-OR-with 95% confidence interval-CI-) with those not receiving BB group in terms of in-hospital and 7-day all-cause mortality, need for hospitalization, and prolonged length of stay (≥7 days). Among the 17 923 recruited patients (median age: 80 years; 56% women), 7795 (43%) were on chronic treatment with BB. Based on the MEESSI-AHF risk score, those on BB were at lower risk. In-hospital mortality was observed in 1310 patients (7.4%), 7-day mortality in 765 (4.3%), need for hospitalization in 13 428 (75.0%), and prolonged length of stay (43.3%). After adjustment for confounding, those on chronic BB were at lower risk for in-hospital all-cause mortality (OR = 0.85, 95% CI = 0.79-0.92, P < 0.001); 7-day all-cause mortality (OR = 0.77, 95% CI = 0.70-0.85, P < 0.001); need for hospitalization (OR = 0.89, 95% CI = 0.85-0.94, P < 0.001); prolonged length of stay (OR = 0.90, 95% CI = 0.86-0.94, P < 0.001). A propensity matching approach yielded consistent findings. Conclusion: in patients presenting to ED with AHF, those on BB had better short-term outcomes than those not receiving BB.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Jacob J, Haro A, Tost J, Rossello X, Llorens P, Herrero P, et al. Short-term outcomes by chronic betablocker treatment in patients presenting to emergency departments with acute heart failure: BB-EAHFE. Eur Heart J Acute Cardiovasc Care. 2022 Nov 2; 11(10): 761-71. DOI: 10.1093/ehjacc/zuac100
  • dc.identifier.doi http://dx.doi.org/10.1093/ehjacc/zuac100
  • dc.identifier.issn 2048-8726
  • dc.identifier.uri http://hdl.handle.net/10230/55606
  • dc.language.iso eng
  • dc.publisher Oxford University Press
  • dc.rights © Oxford University Press. This is a pre-copyedited, author-produced version of an article accepted for publication in European heart journal. Acute cardiovascular care following peer review. The version of record Jacob J, Haro A, Tost J, Rossello X, Llorens P, Herrero P, et al. Short-term outcomes by chronic betablocker treatment in patients presenting to emergency departments with acute heart failure: BB-EAHFE. Eur Heart J Acute Cardiovasc Care. 2022 Nov 2; 11(10): 761-71, is available online at: Jacob J, Haro A, Tost J, Rossello X, Llorens P, Herrero P, et al. Short-term outcomes by chronic betablocker treatment in patients presenting to emergency departments with acute heart failure: BB-EAHFE. Eur Heart J Acute Cardiovasc Care. 2022 Nov 2; 11(10): 761-71. https://academic.oup.com/ehjacc/article-abstract/11/10/761/6677201?redirectedFrom=fulltext&login=true. DOI: 10.1093/ehjacc/zuac100.
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.subject.keyword Acute heart failure
  • dc.subject.keyword Betablockers chronic
  • dc.subject.keyword Mortality
  • dc.subject.keyword Outcomes
  • dc.subject.keyword Prognosis
  • dc.title Short-term outcomes by chronic betablocker treatment in patients presenting to emergency departments with acute heart failure: BB-EAHFE
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/acceptedVersion

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