Accuracy of Colon Capsule Endoscopy in Detecting Colorectal Polyps in Individuals with Familial Colorectal Cancer: Could We Avoid Colonoscopies?
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- dc.contributor.author Alvarez-Urturi, Ana Cristinaca
- dc.contributor.author Fernández-Esparrach, Gloriaca
- dc.contributor.author Ibáñez Zafón, Inés Anaca
- dc.contributor.author Rodríguez De Miguel, Cristinaca
- dc.contributor.author Dedeu Cusco, Josep Mariaca
- dc.contributor.author Bessa Caserras, Xavierca
- dc.contributor.author Córdova, Henryca
- dc.contributor.author Pellisé, Mariaca
- dc.contributor.author Balaguer, Francescca
- dc.contributor.author Ginés, Angelsca
- dc.contributor.author Barranco Priego, Luis Eugenioca
- dc.contributor.author Araujo, Isis K.ca
- dc.contributor.author Andreu García, Montserratca
- dc.contributor.author Llach, Josepca
- dc.contributor.author Castells, Antonica
- dc.contributor.author González-Suarez, Begoñaca
- dc.date.accessioned 2018-01-16T08:19:00Z
- dc.date.available 2018-01-16T08:19:00Z
- dc.date.issued 2017
- dc.description.abstract Background. Individuals with a family history of colorectal cancer (CRC) have an increased risk of CRC. We evaluated the diagnostic yield of CCE in the detection of lesions and also two different colon preparations. Methods. A prospective multicenter study was designed to assess CCE diagnostic yield in a cohort of asymptomatic individuals with a family history of CRC. CCE and colonoscopy were performed on the same day by 2 endoscopists who were blinded to the results of the other procedure. Results. Fifty-three participants were enrolled. The sensitivity, specificity, PPV, and NPV of CCE for detecting advanced adenomas were 100%, 98%, 67%, and 100%. Sensitivity, specificity, PPV, and NPV of CCE for the diagnosis of individuals with polyps were 87%, 97%, 93%, and 88%, respectively. CCE identify 100% of individuals with significant or advanced lesions. Overall cleanliness was adequate by 60.7% of them. The PEG-ascorbic boost seems to improve colon cleanliness, with similar colonic transit time. Conclusion. CCE is a promising tool, but it has to be considered as an alternative technique in this population in order to reduce the number of colonoscopies performed. More studies are needed to understand appropriate screening follow-up intervals and optimize the bowel preparation regimen.
- dc.format.mimetype application/pdfca
- dc.identifier.citation Alvarez-Urturi C, Fernández-Esparrach G, Ibáñez IA, Rodríguez De Miguel C, Dedeu JM, Bessa X. et al. Accuracy of Colon Capsule Endoscopy in Detecting Colorectal Polyps in Individuals with Familial Colorectal Cancer: Could We Avoid Colonoscopies?. Gastroenterol Res Pract. 2017;2017:1507914. DOI: 10.1155/2017/1507914
- dc.identifier.doi http://dx.doi.org/10.1155/2017/1507914
- dc.identifier.issn 1687-6121
- dc.identifier.uri http://hdl.handle.net/10230/33634
- dc.language.iso eng
- dc.publisher Hindawica
- dc.relation.ispartof Gastroenterology Research and Practice. 2017;2017:1507914
- dc.rights Copyright © 2017 Cristina Alvarez-Urturi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.subject.other Colonoscòpia
- dc.subject.other Còlon -- Malalties
- dc.title Accuracy of Colon Capsule Endoscopy in Detecting Colorectal Polyps in Individuals with Familial Colorectal Cancer: Could We Avoid Colonoscopies?ca
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion