The association of peripheral arterial occlusive disease with major coronary events in a mediterranean population with low coronary heart disease incidence

Mostra el registre complet Registre parcial de l'ítem

• dc.contributor.author Merino, Jana
• dc.contributor.author Planas, Adriana
• dc.contributor.author Moner, Ana de
• dc.contributor.author Gasol, Ana
• dc.contributor.author Contreras, Carmen
• dc.contributor.author Vidal-Barraquer, Francesc
• dc.contributor.author Marrugat de la Iglesia, Jaume
• dc.contributor.author Clará Velasco, Alberto
• dc.date.accessioned 2025-12-03T14:48:20Z
• dc.date.available 2025-12-03T14:48:20Z
• dc.date.issued 2008
• dc.date.updated 2025-12-03T14:48:20Z
• dc.description.abstract Objectives: The association of peripheral arterial occlusive disease (PAD) association with major coronary events (MCE) has been well documented, nevertheless data are lacking for populations with a low incidence of coronary heart disease (CHD). We aimed to assess the association of PAD with MCE in a Mediterranean population. Design: Prospective survey of 699 55-74 year-old men representative of an urban district near Barcelona (Spain). Methods: Baseline cardiovascular risk factors, CHD and PAD (ankle/brachial index<0.9) were recorded. MCE were evaluated during the 5-year follow-up. Results: At recruitment 94 subjects (13.4%) had PAD. During follow-up (mean 69.3 months), 35 (5%) subjects suffered a MCE, of whom 12 had PAD, 9 previous symptomatic CHD and 1 subject both conditions. Higher CHD related mortality (8.6% vs 1.4%; p<0.001) and lower MCE-free survival (78.67% vs 93.26%; p<0.001) was observed for PAD subjects. On Cox regression analysis PAD (RR=3; p=0.003) and previous symptomatic CHD (RR=4.1; p<0.001) were associated independently with MCE during follow-up. Conclusions: Even in a population with a low incidence of CHD there is a strong relationship between PAD and future MCE. Screening for PAD may improve the selection of patients targeted for cardiovascular risk prevention.
• dc.format.mimetype application/pdf
• dc.identifier.citation Merino J, Planas A, De Moner A, Gasol A, Contreras C, Marrugat J, Vidal-Barraquer F, Clarà A. The association of peripheral arterial occlusive disease with major coronary events in a mediterranean population with low coronary heart disease incidence. Eur J Vasc Endovasc Surg. 2008 Jul;36(1):71-6. DOI: 10.1016/j.ejvs.2008.01.029
• dc.identifier.doi http://dx.doi.org/10.1016/j.ejvs.2008.01.029
• dc.identifier.issn 1078-5884
• dc.identifier.uri http://hdl.handle.net/10230/72116
• dc.language.iso eng
• dc.publisher Elsevier
• dc.relation.ispartof European journal of vascular and endovascular surgery: the official journal of the European Society for Vascular Surgery. 2008;36(1):71-6. DOI: 10.1016/j.ejvs.2008.01.029
• dc.rights © Elsevier http://dx.doi.org/10.1016/j.ejvs.2008.01.029
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.subject.keyword Cardiovascular diseases
• dc.subject.keyword Risk factors
• dc.subject.keyword Cohort studies
• dc.subject.keyword Peripheral vascular diseases
• dc.subject.keyword Coronary disease
• dc.title The association of peripheral arterial occlusive disease with major coronary events in a mediterranean population with low coronary heart disease incidence
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/acceptedVersion