Psychoeducation for bipolar disorder and risk of recurrence and hospitalization - a within-individual analysis using registry data

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• dc.contributor.author Joas, Erik
• dc.contributor.author Bäckman, Kristoffer
• dc.contributor.author Karanti, Alina
• dc.contributor.author Sparding, Timea
• dc.contributor.author Colom, Francesc
• dc.contributor.author Pålsson, Erik
• dc.contributor.author Landén, Mikael
• dc.date.accessioned 2020-06-18T06:39:25Z
• dc.date.available 2020-06-18T06:39:25Z
• dc.date.issued 2020
• dc.description.abstract Background: The efficacy of psychoeducation for bipolar disorder has been demonstrated in clinical trials, but it is not known if the results translate into effectiveness in routine clinical practice. The aim was to determine the effectiveness of psychoeducation for bipolar disorder in a routine clinical setting. Method: We identified 2819 patients with at least three registrations in the Swedish Quality Assurance Register for Bipolar Disorder. Among those, 402 had not been exposed to psychoeducation at the first visit, but received psychoeducation during any of the following registrations. Using within-individual analyses, the risk of recurrence after having received psychoeducation was compared with the risk prior to psychoeducation. Results: In adjusted within-individuals comparisons, periods after psychoeducation was associated with decreased risks of any recurrence [odds ratio (OR) 0.57, 95% CI 0.42-0.78], (hypo-)manic or mixed episodes (OR 0.54, 95% CI 0.39-0.76), depressive episodes (OR 0.63, 95% CI 0.47-0.86), and inpatient care (OR 0.54, 95% CI 0.33-0.86) relative to periods prior to psychoeducation. There was no association with rates of involuntary sectioning or suicide attempts. Conclusions: The results suggest that psychoeducation for bipolar disorder reduces the risk of mood episodes and inpatient care also when implemented in routine clinical practice.
• dc.format.mimetype application/pdf
• dc.identifier.citation Joas E, Bäckman K, Karanti A, Sparding T, Colom F, Pålsson E, et al. Psychoeducation for bipolar disorder and risk of recurrence and hospitalization - a within-individual analysis using registry data. Psychol Med. 2020 Apr; 50(6):1043-49. DOI: 10.1017/S0033291719001053
• dc.identifier.doi http://dx.doi.org/10.1017/S0033291719001053
• dc.identifier.issn 0033-2917
• dc.identifier.uri http://hdl.handle.net/10230/45009
• dc.language.iso eng
• dc.publisher Cambridge University Press
• dc.rights Copyright © The Author(s) 2019. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Bipolar disorders
• dc.subject.keyword Epidemiology
• dc.subject.keyword Psychoeducation
• dc.title Psychoeducation for bipolar disorder and risk of recurrence and hospitalization - a within-individual analysis using registry data
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion