Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study
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- dc.contributor.author Benaiges Foix, David
- dc.contributor.author Bisbe Maria
- dc.contributor.author Pedro-Botet, Juan Carlos
- dc.contributor.author Vargas-Machuca, Aleix de
- dc.contributor.author Ramón Moros, José Manuel
- dc.contributor.author Pera Roman, Manuel Ramón
- dc.contributor.author Villatoro Moreno, Montserrat
- dc.contributor.author Fontane Francia, Laia
- dc.contributor.author Julià, Helena
- dc.contributor.author Climent Biescas, Elisenda
- dc.contributor.author Castañer, Olga
- dc.contributor.author Flores-Le-Roux, Juana Antonia
- dc.contributor.author Goday Arno, Alberto
- dc.date.accessioned 2021-10-14T06:47:47Z
- dc.date.available 2021-10-14T06:47:47Z
- dc.date.issued 2020
- dc.description.abstract To ascertain the 5-year metabolic effects of bariatric surgery in poor weight loss (WL) responders and establish associated factors. Methods: Retrospective analysis of a non-randomised prospective cohort of bariatric surgery patients completing a 5-year follow-up. Mid-term poor WL was considered when 5-year excess weight loss was <50%. Results: Forty-three (20.3%) of the 212 included patients were mid-term poor WL responders. They showed an improvement in all metabolic markers at 2 years, except for total cholesterol. This improvement with respect to baseline was maintained at 5 years for plasma glucose, HbA1c, HOMA, HDL and diastolic blood pressure; however, LDL cholesterol, triglycerides and systolic blood pressure were similar to presurgical values. Comorbidity remission rates were comparable to those obtained in the good WL group except for hypercholesterolaemia (45.8% vs. poor WL, p = 0.005). On multivariate analysis, lower baseline HDL cholesterol levels, advanced age and lower preoperative weight loss were independently associated with poor mid-term WL. Conclusions: Although that 1 in 5 patients presented suboptimal WL 5 years after bariatric surgery, other important metabolic benefits were maintained.
- dc.format.mimetype application/pdf
- dc.identifier.citation Benaiges D, Bisbe M, Pedro-Botet J, de Vargas-Machuca A, Ramon JM, Pera M, et al. Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study. J Clin Med. 2020 Oct 1; 9(10): 3193. DOI: 10.3390/jcm9103193
- dc.identifier.doi http://dx.doi.org/10.3390/jcm9103193
- dc.identifier.issn 2077-0383
- dc.identifier.uri http://hdl.handle.net/10230/48649
- dc.language.iso eng
- dc.publisher MDPI
- dc.rights © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Bariatric surgery
- dc.subject.keyword Gastric bypass
- dc.subject.keyword Obesity
- dc.subject.keyword Severe obesity
- dc.subject.keyword Sleeve gastrectomy;
- dc.subject.keyword Weight loss
- dc.subject.keyword Weight regain
- dc.title Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion