Updated guidelines for predictive biomarker testing in advanced non-small-cell lung cancer: a national consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology

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  • dc.contributor.author Garrido, P.
  • dc.contributor.author Conde, Esther
  • dc.contributor.author De Castro, Javier
  • dc.contributor.author Gómez-Román, J. J.
  • dc.contributor.author Felip, Enriqueta
  • dc.contributor.author Pijuan Andujar, Lara
  • dc.contributor.author Isla, Dolores
  • dc.contributor.author Sanz, J.
  • dc.contributor.author Paz-Ares, L.
  • dc.contributor.author López-Ríos, F.
  • dc.date.accessioned 2020-05-08T07:34:49Z
  • dc.date.issued 2020
  • dc.description.abstract In 2011 the Spanish Society of Medical Oncology (SEOM) and the Spanish Society of Pathology (SEAP) started a joint project to establish guidelines on biomarker testing in patients with advanced non-small-cell lung cancer (NSCLC) based on current evidence. As this field is constantly evolving, these guidelines have been updated, previously in 2012 and 2015 and now in 2019. Current evidence suggests that the mandatory tests to conduct in all patients with advanced NSCLC are for EGFR and BRAF mutations, ALK and ROS1 rearrangements and PD-L1 expression. The growing need to study other emerging biomarkers has promoted the routine use of massive sequencing (next-generation sequencing, NGS). The coordination of every professional involved and the prioritisation of the most suitable tests and technologies for each case remains a challenge.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Garrido P, Conde E, de Castro J, Gómez-Román JJ, Felip E, Pijuan L, et al. Updated guidelines for predictive biomarker testing in advanced non-small-cell lung cancer: a national consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology. Clin Transl Oncol. 2020 Jul;22(7):989-1003. DOI: 10.1007/s12094-019-02218-4
  • dc.identifier.doi http://dx.doi.org/10.1007/s12094-019-02218-4
  • dc.identifier.issn 1699-048X
  • dc.identifier.uri http://hdl.handle.net/10230/44463
  • dc.language.iso eng
  • dc.publisher Springer
  • dc.relation.ispartof Clinical and Translational Oncology. 2020 Jul;22(7):989-1003.
  • dc.rights © Springer The final publication is available at Springer via http://dx.doi.org/10.1007/s12094-019-02218-4
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.subject.keyword ALK
  • dc.subject.keyword BRAF
  • dc.subject.keyword Biomarkers
  • dc.subject.keyword EGFR
  • dc.subject.keyword Non-small-cell lung cancer
  • dc.subject.keyword PD-L1
  • dc.subject.keyword ROS1
  • dc.title Updated guidelines for predictive biomarker testing in advanced non-small-cell lung cancer: a national consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/acceptedVersion