A forensic population database in El Salvador: 58 STRs and 94 SNPs

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• dc.contributor.author Casals López, Ferran
• dc.contributor.author Rasal Soteras, Raquel
• dc.contributor.author Anglada Busquets, Roger
• dc.contributor.author Tormo, Marc
• dc.contributor.author Bonet, Núria
• dc.contributor.author Rivas, Nury
• dc.contributor.author Vásquez, Patricia
• dc.contributor.author Calafell i Majó, Francesc
• dc.date.accessioned 2022-01-20T07:06:48Z
• dc.date.issued 2021
• dc.description.abstract We have genotyped the 58 STRs (27 autosomal, 24 Y-STRs and 7 X-STRs) and 94 autosomal SNPs in Illumina ForenSeq™ Primer Mix A in a sample of 248 men and 143 women from El Salvador, Central America. Regional division (Centro, Oriente, Occidente) showed in almost all cases FST values not significantly different from 0, and further analyses were applied only to the undivided, country-wide population. The overall random match probability (RMP) decreased from 6.79 × 10-31 in length-based genotypes in the 27 autosomal STRs to 1.47 × 10-34 in repeat-sequence based genotypes. Combining the autosomal loci in this set, RMP reaches 2.97 × 10-70. In a population genetic analysis, El Salvador showed the lowest FST values with US Hispanics both for autosomal and X-STRs; however, it was much closer to Native Americans for the latter than for the former, in accordance with the well-known gender-biased admixture that created most Latin American populations.
• dc.description.sponsorship This work was supported by the Spanish Ministry of Economy and Competitiveness and Agencia Estatal de Investigación (grant numbers CGL2016–75389-P (MINEICO/FEDER, UE), PID2019–106485GB-I00/AEI/10.13039/501100011033 (MINEICO), and “Unidad María de Maeztu” (MDM-2014–0370) to FCal; Agència de Gestió d′Ajuts Universitaris i de la Recerca (Generalitat de Catalunya, grant 2017SGR00702); Agència Catalana de Cooperació al Desenvolupament (ACCD004/17/00019 and ACCD016/18/00031); Fundación Panamericana para el Desarrollo (PADF, No. PRDHD-RFA-R-2017–009). We thank also the Ministry of Health of El Salvador, which, in 2018, allowed us to take samples at their facilities.
• dc.format.mimetype application/pdf
• dc.identifier.citation Casals F, Rasal R, Anglada R, Tormo M, Bonet N, Rivas N, Vásquez P, Calafell F. A forensic population database in El Salvador: 58 STRs and 94 SNPs. Forensic Sci Int Genet. 2021;57:102646. DOI: 10.1016/j.fsigen.2021.102646
• dc.identifier.doi http://dx.doi.org/10.1016/j.fsigen.2021.102646
• dc.identifier.issn 1872-4973
• dc.identifier.uri http://hdl.handle.net/10230/52268
• dc.language.iso eng
• dc.publisher Elsevier
• dc.relation.ispartof Forensic Sci Int Genet. 2021;57:102646
• dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/CGL2016-75389-P
• dc.relation.projectID info:eu-repo/grantAgreement/ES/2PE/PID2019-106485GB-I00
• dc.rights © Elsevier http://dx.doi.org/10.1016/j.fsigen.2021.102646
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.subject.keyword Massive parallel sequencing
• dc.subject.keyword Missing persons
• dc.subject.keyword Repeat sequence-based alleles
• dc.title A forensic population database in El Salvador: 58 STRs and 94 SNPs
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/acceptedVersion