Increased ultra-processed food consumption is associated with worsening of cardiometabolic risk factors in adults with metabolic syndrome: Longitudinal analysis from a randomized trial

Mostra el registre complet Registre parcial de l'ítem

• dc.contributor.author González-Palacios, Sandra
• dc.contributor.author Schröder, Helmut, 1958-
• dc.contributor.author Zomeño Fajardo, Maria Dolores
• dc.contributor.author Pérez-Vega, Karla Alejandra
• dc.contributor.author PREDIMED‐Plus Trial Investigators
• dc.date.accessioned 2024-02-22T07:08:45Z
• dc.date.available 2024-02-22T07:08:45Z
• dc.date.issued 2023
• dc.description.abstract Background and aims: The association between changes in ultra-processed food (UPF) consumption and cardiometabolic risk (CMR) factors remains understudied. We evaluated the association between changes in UPF consumption over 12 months of follow-up and changes in CMR factors in adults diagnosed with metabolic syndrome. Methods: We analysed data from 5373 adults (aged 55-75 years) participating in the PREDIMED-Plus trial. Diet was evaluated at baseline, 6- and 12-month visits using a validated food frequency questionnaire, and UPF consumption (in grams/day and percentage of total daily dietary intake in grams) was categorized based on NOVA classification. We used mixed-effects linear models with repeated measurements at baseline, 6 and 12 months of follow-up to assess the associations between changes in UPF consumption and changes in CMR factors adjusting for sociodemographic and lifestyles variables. Results: In multivariable-adjusted models, when comparing the highest versus the lowest quartile of UPF consumption, positive associations were found for several CMR factors: weight (kg, β = 1.09; 95% confidence interval 0.91 to 1.26); BMI (kg/m2, β = 0.39; 0.33 to 0.46); waist circumference (cm, β = 1.03; 0.81 to 1.26); diastolic blood pressure (mm Hg, β = 0.67; 0.29 to 1.06); fasting blood glucose (mg/dl, β = 1.66; 0.61 to 2.70); HbA1c (%, β = 0.04; 0.01 to 0.07); triglycerides (mg/dl, β = 6.79; 3.66 to 9.91) and triglycerides and glucose index (β = 0.06; 0.04 to 0.08). Conclusions: Higher UPF consumption was associated with adverse evolution in objectively measured CMR factors after 12 months of follow-up in adults with metabolic syndrome. Further research is needed to explore whether these changes persist for longer periods.
• dc.format.mimetype application/pdf
• dc.identifier.citation González-Palacios S, Oncina-Cánovas A, García-de-la-Hera M, Martínez-González MÁ, Salas-Salvadó J, Corella D et al. Increased ultra-processed food consumption is associated with worsening of cardiometabolic risk factors in adults with metabolic syndrome: Longitudinal analysis from a randomized trial. Atherosclerosis. 2023 Jul;377:12-23. DOI: 10.1016/j.atherosclerosis.2023.05.022
• dc.identifier.doi http://dx.doi.org/10.1016/j.atherosclerosis.2023.05.022
• dc.identifier.issn 0021-9150
• dc.identifier.uri http://hdl.handle.net/10230/59214
• dc.language.iso eng
• dc.publisher Elsevier
• dc.relation.ispartof Atherosclerosis. 2023 Jul;377:12-23
• dc.rights © 2023 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/bync-nd/4.0/
• dc.subject.keyword Blood pressure
• dc.subject.keyword Body mass index
• dc.subject.keyword Cardiometabolic risk factors
• dc.subject.keyword Fasting blood glucose
• dc.subject.keyword Metabolic syndrome
• dc.subject.keyword Ultra-processed foods
• dc.title Increased ultra-processed food consumption is associated with worsening of cardiometabolic risk factors in adults with metabolic syndrome: Longitudinal analysis from a randomized trial
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion