Recommendations for living donor kidney transplantation
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- dc.contributor.author Frutos, Miguel Ángel
- dc.contributor.author Crespo Barrio, Marta
- dc.contributor.author Pascual Santos, Julio
- dc.date.accessioned 2023-05-04T06:20:24Z
- dc.date.available 2023-05-04T06:20:24Z
- dc.date.issued 2022
- dc.description.abstract This Guide for Living Donor Kidney Transplantation (LDKT) has been prepared with the sponsorship of the Spanish Society of Nephrology (SEN), the Spanish Transplant Society (SET), and the Spanish National Transplant Organization (ONT). It updates evidence to offer the best chronic renal failure treatment when a potential living donor is available. The core aim of this Guide is to supply clinicians who evaluate living donors and transplant recipients with the best decision-making tools, to optimise their outcomes. Moreover, the role of living donors in the current KT context should recover the level of importance it had until recently. To this end the new forms of incompatible HLA and/or ABO donation, as well as the paired donation which is possible in several hospitals with experience in LDKT, offer additional ways to treat renal patients with an incompatible donor. Good results in terms of patient and graft survival have expanded the range of circumstances under which living renal donors are accepted. Older donors are now accepted, as are others with factors that affect the decision, such as a borderline clinical history or alterations, which when evaluated may lead to an additional number of transplantations. This Guide does not forget that LDKT may lead to risk for the donor. Pre-donation evaluation has to centre on the problems which may arise over the short or long-term, and these have to be described to the potential donor so that they are able take them into account. Experience over recent years has led to progress in risk analysis, to protect donors' health. This aspect always has to be taken into account by LDKT programmes when evaluating potential donors. Finally, this Guide has been designed to aid decision-making, with recommendations and suggestions when uncertainties arise in pre-donation studies. Its overarching aim is to ensure that informed consent is based on high quality studies and information supplied to donors and recipients, offering the strongest possible guarantees.
- dc.format.mimetype application/pdf
- dc.identifier.citation Frutos MÁ, Crespo M, Valentín MO, Alonso-Melgar Á, Alonso J, Fernández C, et al. Recommendations for living donor kidney transplantation. Nefrologia (Engl Ed). 2022 Dec;42 Suppl 2:5-132. DOI: 10.1016/j.nefroe.2022.07.001
- dc.identifier.doi http://dx.doi.org/10.1016/j.nefroe.2022.07.001
- dc.identifier.issn 2013-2514
- dc.identifier.uri http://hdl.handle.net/10230/56668
- dc.language.iso eng
- dc.publisher Elsevier
- dc.relation.ispartof Nefrologia (Engl Ed). 2022 Dec;42 Suppl 2:5-132
- dc.rights © Published by Elsevier España, S.L.U. on behalf of Sociedad Española de Nefrología. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
- dc.subject.keyword Living kidney donor
- dc.subject.keyword Living kidney transplant
- dc.subject.keyword Guidelines
- dc.subject.keyword Renal transplantation
- dc.subject.keyword Legal
- dc.subject.keyword Ethical
- dc.subject.keyword Surgical
- dc.subject.keyword Immunosuppression
- dc.subject.keyword Living donor nephrectomy
- dc.subject.keyword ABO incompatible
- dc.subject.keyword HLA incompatible
- dc.subject.keyword Paired renal transplant
- dc.subject.keyword End stage renal disease
- dc.subject.keyword Altruistic donor
- dc.subject.keyword Donor protection
- dc.subject.keyword Donor profile
- dc.subject.keyword Donor risks
- dc.subject.keyword Donor lifestyle
- dc.subject.keyword Crossmatch
- dc.subject.keyword HLA typing
- dc.subject.keyword Incompatibility
- dc.subject.keyword Surgical complications
- dc.subject.keyword Retransplants
- dc.subject.keyword Paediatric transplant
- dc.subject.keyword Desensitization
- dc.subject.keyword Survival
- dc.subject.keyword Rejection
- dc.title Recommendations for living donor kidney transplantation
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion