An intensive, structured, mobile devices-based healthcare intervention to optimize the lipid-lowering therapy improves lipid control after an acute coronary syndrome

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• dc.contributor.author Ruiz-Bustillo, Sonia
• dc.contributor.author Badosa Marcé, Neus
• dc.contributor.author Cabrera-Aguilera, Ignacio
• dc.contributor.author Ivern Díaz, Consol
• dc.contributor.author Llagostera Martín, Marc
• dc.contributor.author Mojón Álvarez, Diana
• dc.contributor.author Vicente Elcano, Miren
• dc.contributor.author Ribas Barquet, Núria
• dc.contributor.author Recasens, Lluís
• dc.contributor.author Marti-Almor, Julio
• dc.contributor.author Cladellas Capdevila, M.Mercedes
• dc.contributor.author Farré López, Núria
• dc.date.accessioned 2023-02-08T08:49:07Z
• dc.date.available 2023-02-08T08:49:07Z
• dc.date.issued 2022
• dc.description.abstract Aims: despite the evidence, lipid-lowering treatment (LLT) in secondary prevention remains insufficient, and a low percentage of patients achieve the recommended LDL cholesterol (LDLc) levels by the guidelines. We aimed to evaluate the efficacy of an intensive, mobile devices-based healthcare lipid-lowering intervention after hospital discharge in patients hospitalized for acute coronary syndrome (ACS). Methods and results: ambiespective register in which a mobile devices-based healthcare intervention including periodic follow-up, serial lipid level controls, and optimization of lipid-lowering therapy, if appropriate, was assessed in terms of serum lipid-level control at 12 weeks after discharge. A total of 497 patients, of which 462 (93%) correctly adhered to the optimization protocol, were included in the analysis. At the end of the optimization period, 327 (70.7%) patients had LDLc levels ≤ 70 mg/dL. 40% of patients in the LDLc ≤ 70 mg/dL group were upgraded to very-high intensity lipid-lowering ability therapy vs. 60.7% in the LDLc > 70 mg/dL group, p < 0.001. Overall, 38.5% of patients had at least a change in their LLT. Side effects were relatively infrequent (10.7%). At 1-year follow-up, LDLc levels were measured by the primary care physician in 342 (68.8%) of the whole cohort of 497 patients. In this group, 71.1% of patients had LDLc levels ≤ 70 mg/dL. Conclusion: an intensive, structured, mobile devices-based healthcare intervention after an ACS is associated with more than 70% of patients reaching the LDLc levels recommended by the clinical guidelines. In patients with LDLc measured at 1-year follow-up, 71.1% had LDLc levels ≤ 70 mg/dL.
• dc.format.mimetype application/pdf
• dc.identifier.citation Ruiz-Bustillo S, Badosa N, Cabrera-Aguilera I, Ivern C, Llagostera M, Mojón D, et al. An intensive, structured, mobile devices-based healthcare intervention to optimize the lipid-lowering therapy improves lipid control after an acute coronary syndrome. Front Cardiovasc Med. 2022 Jul 26; 9: 916031. DOI: 10.3389/fcvm.2022.916031
• dc.identifier.doi http://dx.doi.org/10.3389/fcvm.2022.916031
• dc.identifier.issn 2297-055X
• dc.identifier.uri http://hdl.handle.net/10230/55677
• dc.language.iso eng
• dc.publisher Frontiers
• dc.rights Copyright © 2022 Ruiz-Bustillo, Badosa, Cabrera-Aguilera, Ivern, Llagostera, Mojón, Vicente, Ribas, Recasens, Martí-Almor, Cladellas and Farré. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) http://creativecommons.org/licenses/by/4.0/. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Cardiovascular risk factors
• dc.subject.keyword Ischemic heart disease
• dc.subject.keyword Lipid-lowering therapy
• dc.subject.keyword Mobile devices-based healthcare
• dc.subject.keyword Secondary prevention
• dc.title An intensive, structured, mobile devices-based healthcare intervention to optimize the lipid-lowering therapy improves lipid control after an acute coronary syndrome
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion