Modulation of Nrf2 by olive oil and wine polyphenols and neuroprotection

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  • dc.contributor.author Martínez-Huélamo, Miriamca
  • dc.contributor.author Rodríguez-Morató, Jose, 1987-ca
  • dc.contributor.author Boronat Rigol, Anna, 1990-ca
  • dc.contributor.author Torre Fornell, Rafael de laca
  • dc.date.accessioned 2018-04-04T07:30:19Z
  • dc.date.available 2018-04-04T07:30:19Z
  • dc.date.issued 2017
  • dc.description.abstract Strong adherence to a Mediterranean diet is associated with improved cognitive function and a lower prevalence of mild cognitive impairment. Olive oil and red wine are rich sources of polyphenols which are responsible in part for the beneficial effects on cognitive functioning. Polyphenols induce endogenous antioxidant defense mechanisms by modulating transcription factors such as the nuclear factor (erythroid-derived 2)-like 2 (Nrf2). This review discusses the scientific data supporting the modulating effect of olive oil and red wine polyphenols on Nrf2 expression, and the potential health benefits associated with cognitive functioning.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Martínez-Huélamo M, Rodríguez-Morató J, Boronat A, de la Torre R. Modulation of Nrf2 by Olive Oil and Wine Polyphenols and Neuroprotection. Antioxidants (Basel). 2017 Sep 26;6(4):73. DOI: 10.3390/antiox6040073
  • dc.identifier.doi http://dx.doi.org/10.3390/antiox6040073
  • dc.identifier.issn 2076-3921
  • dc.identifier.uri http://hdl.handle.net/10230/34283
  • dc.language.iso eng
  • dc.publisher MDPIca
  • dc.relation.ispartof Antioxidants (Basel). 2017 Sep 26;6(4):73
  • dc.rights Copyright © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by/4.0/
  • dc.subject.keyword Nrf2
  • dc.subject.keyword Cognitive function
  • dc.subject.keyword Hydroxytyrosol
  • dc.subject.keyword Olive oil
  • dc.subject.keyword Polyphenols
  • dc.subject.keyword Resveratrol
  • dc.subject.keyword Wine
  • dc.subject.other Oli d'oliva -- Aspectes nutricionals
  • dc.subject.other Vi -- Efectes fisiològics
  • dc.title Modulation of Nrf2 by olive oil and wine polyphenols and neuroprotectionca
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion