Ventromedial and dorsolateral prefrontal interactions underlie will to fight and die for a cause
Mostra el registre complet Registre parcial de l'ítem
- dc.contributor.author Pretus, Clara
- dc.contributor.author Hamid, Nafees
- dc.contributor.author Sheikh, Hammad
- dc.contributor.author Gómez, Angel
- dc.contributor.author Ginges, Jeremy
- dc.contributor.author Tobeña, Adolf
- dc.contributor.author Davis, Richard
- dc.contributor.author Vilarroya, Óscar
- dc.contributor.author Atran, Scott
- dc.date.accessioned 2021-02-19T08:00:21Z
- dc.date.available 2021-02-19T08:00:21Z
- dc.date.issued 2019
- dc.description.abstract Willingness to fight and die (WFD) has been developed as a measure to capture willingness to incur costly sacrifices for the sake of a greater cause in the context of entrenched conflict. WFD measures have been repeatedly used in field studies, including studies on the battlefield, although their neurofunctional correlates remain unexplored. Our aim was to identify the neural underpinnings of WFD, focusing on neural activity and interconnectivity of brain areas previously associated with value-based decision-making, such as the ventromedial prefrontal cortex (vmPFC) and the dorsolateral prefrontal cortex (dlPFC). A sample of Pakistani participants supporting the Kashmiri cause was selected and invited to participate in an functional magnetic resonance (fMRI) paradigm where they were asked to convey their WFD for a series of values related to Islam and current politics. As predicted, higher compared to lower WFD was associated with increased ventromedial prefrontal activity and decreased dorsolateral activity, as well as lower connectivity between the vmPFC and the dlPFC. Our findings suggest that WFD more prominently relies on brain areas typically associated with subjective value (vmPFC) rather than integration of material costs (dlPFC) during decision-making, supporting the notion that decisions on costly sacrifices may not be mediated by cost-benefit computation.
- dc.description.sponsorship This work was supported by the Minerva Program and the Air Force Office of Scientific Research of the U.S. Department of Defense (AFOSR FA9550-14-1-0030 DEF) and the BIAL Foundation (Grant #163/14) and the Ministerio de Ciencia, Innovación y Universidades (RTI2018-093550-B-I00).
- dc.format.mimetype application/pdf
- dc.identifier.citation Pretus C, Hamid N, Sheikh H, Gómez Á, Ginges J, Tobeña A, et al. Ventromedial and dorsolateral prefrontal interactions underlie will to fight and die for a cause. Soc Cogn Affect Neurosci. 2019 Aug 7; 14(6):569-77. DOI: 10.1093/scan/nsz034
- dc.identifier.doi http://dx.doi.org/10.1093/scan/nsz034
- dc.identifier.issn 1749-5016
- dc.identifier.uri http://hdl.handle.net/10230/46543
- dc.language.iso eng
- dc.publisher Oxford University Press
- dc.relation.projectID info:eu-repo/grantAgreement/ES/2PE/RTI2018-093550-B-I00
- dc.rights Copyright © The Author(s) 2019. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
- dc.subject.keyword Costly sacrifices
- dc.subject.keyword fMRI
- dc.subject.keyword Functional connectivity
- dc.subject.keyword Sacred values
- dc.subject.keyword Will to fight and die
- dc.title Ventromedial and dorsolateral prefrontal interactions underlie will to fight and die for a cause
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion