Radiofrequency-assisted transection of the pancreas vs stapler in distal pancreatectomy: a propensity score matched cohort analysis

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• dc.contributor.author Pueyo Périz, Eva M.
• dc.contributor.author Téllez-Marquès, C.
• dc.contributor.author Radosevic, Aleksandar, 1974-
• dc.contributor.author Morató Redondo, Olga
• dc.contributor.author Visa Turmo, Laura
• dc.contributor.author Ilzarbe Sánchez, Lucas
• dc.contributor.author Berjano, Enrique J.
• dc.contributor.author de Vicente, E.
• dc.contributor.author Poves Prim, José Ignacio
• dc.contributor.author Ielpo, Benedetto
• dc.contributor.author Grande Posa, Luís
• dc.contributor.author Burdío Pinilla, Fernando
• dc.contributor.author Sánchez Velázquez, Patricia, 1985-
• dc.date.accessioned 2022-12-13T06:54:45Z
• dc.date.available 2022-12-13T06:54:45Z
• dc.date.issued 2022
• dc.description.abstract To demonstrate the efficacy of radiofrequency for pancreatic stump closure in reducing the incidence of postoperative pancreatic fistula (POPF) in distal pancreatectomy (DP) compared with mechanical transection methods. Despite all the different techniques of pancreatic stump closure proposed for DP, best practice for avoiding POPF remains an unresolved issue, with an incidence of up to 30% regardless of center volume or surgical expertise. DP was performed in a cohort of patients by applying radiofrequency to stump closure (RF Group) and compared with mechanical closure (Control Group). A propensity score (PS) matched cohort study was carried out to minimize bias from nonrandomized treatment assignment. Cohorts were matched by PS accounting for factors significantly associated with either undergoing RF transection or mechanical closure through logistic regression analysis. The primary end-point was the incidence of clinically relevant POPF (CR-POPF). Of 89 patients included in the whole cohort, 13 case patients from the RF-Group were 1:1 matched to 13 control patients. In both the first independent analysis of unmatched data and subsequent adjustment to the overall propensity score-matched cohort, a higher rate of CR-POPF in the Control Group compared with the RF-Group was detected (25.4% vs 5.3%, p = 0.049 and 53.8% vs 0%; p = 0.016 respectively). The RF Group showed better outcomes in terms of readmission rate (46.2% vs 0%, p = 0.031). No significant differences were observed in terms of mortality, major complications (30.8% vs 0%, p = 0.063) or length of hospital stay (5.7 vs 5.2 days, p = 0.89). Findings suggest that the RF-assisted technique is more efficacious in reducing CR-POPF than mechanical pancreatic stump closure.
• dc.format.mimetype application/pdf
• dc.identifier.citation Pueyo-Périz E, Téllez-Marquès C, Radosevic A, Morató O, Visa L, et al. Radiofrequency-assisted transection of the pancreas vs stapler in distal pancreatectomy: a propensity score matched cohort analysis. Sci Rep. 2022 May 6; 12(1):7486. DOI: 10.1038/s41598-022-11583-0
• dc.identifier.doi http://dx.doi.org/10.1038/s41598-022-11583-0
• dc.identifier.issn 2045-2322
• dc.identifier.uri http://hdl.handle.net/10230/55101
• dc.language.iso eng
• dc.publisher Nature Research
• dc.rights Copyright © Pueyo-Périz E, Téllez-Marquès C, Radosevic A, Morató O, Visa L, et al. 2022. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.other Radiofreqüència
• dc.subject.other Pàncrees--Cirurgia
• dc.subject.other Pancreatitis
• dc.subject.other Postoperatori
• dc.title Radiofrequency-assisted transection of the pancreas vs stapler in distal pancreatectomy: a propensity score matched cohort analysis
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion