• The evolution of relapse of adult T cell acute lymphoblastic leukemia

  Sentís, Inés; González, Santi; Genescà, Eulalia; García Hernández, Violeta; Muiños, Ferran; González, Celia; López Arribillaga, Erika, 1986-; González, Jessica; Fernández-Ibarrondo, Lierni; Mularoni, Loris; Espinosa-Anke, Luis; Bellosillo Paricio, Beatriz; Ribera, Josep Maria; Bigas Salvans, Anna; González Pérez, Abel; López Bigas, Núria (BioMed Central, 2020)

  Background: Adult T cell acute lymphoblastic leukemia (T-ALL) is a rare disease that affects less than 10 individuals in one million. It has been less studied than its cognate pediatric malignancy, which is more prevalent. ...
• BnpC: Bayesian non-parametric clustering of single-cell mutation profiles

  Borgsmüller, Nico; Bonet, Jose; Marass, Francesco; González Pérez, Abel; López Bigas, Núria; Beerenwinkel, Nico; Beerenwinkel, Nico (Oxford University Press, 2020)

  Motivation: The high resolution of single-cell DNA sequencing (scDNA-seq) offers great potential to resolve intratumor heterogeneity (ITH) by distinguishing clonal populations based on their mutation profiles. However, the ...
• The Rise of shadow banking: evidence from capital regulation

  Irani, Rustom M.; Iyer, Rajkamal; Meisenzahl, Ralf R.; Peydró, José-Luis (Oxford University Press, 2020)

  We investigate the connections between bank capital regulation and the prevalence of lightly regulated nonbanks (shadow banks) in the U.S. corporate loan market. For identification, we exploit a supervisory credit register ...
• Association between lung function decline and obstructive sleep apnoea: the ALEC study

  Emilsson, Össur Ingi; Sundbom, Fredrik; Ljunggren, Mirjam; Benediktsdottir, Bryndis; García Aymerich, Judith; Bui, Dinh Son; Jarvis, Deborah; Olin, Anna-Carin; Franklin, Karl; Demoly, Pascal; Lindberg, Eva; Janson, Christer; Aspelund, Thor; Gislason, Thorarinn (Springer, 2020)

  Purpose: To study changes in lung function among individuals with a risk of obstructive sleep apnoea (OSA), and if asthma affected this relationship. Methods: We used data from the European Community Respiratory Health ...
• Role of DNA methylation in the association of lung function with body mass index: a two-step epigenetic Mendelian randomisation study

  Amaral, André F.S.; Imboden, Medea; Wielscher, Matthias; Rezwan, Faisal I.; Minelli, Cosetta; García Aymerich, Judith; Peralta, Gabriela P.; Auvinen, Juha; Jeong, Ayoung; Schaffner, Emmanuel; Beckmeyer-Borowko, Anna B.; Holloway, John W.; Jarvelin, Marjo-Riitta; Probst-Hensch, Nicole; Jarvis, Deborah; ALEC consortium (BioMed Central, 2020)

  Background: Low lung function has been associated with increased body mass index (BMI). The aim of this study was to investigate whether the effect of BMI on lung function is mediated by DNA methylation. Methods: We used ...
• Parents' smoking onset before conception as related to body mass index and fat mass in adult offspring: Findings from the RHINESSA generation study

  Knudsen, Gerd Toril Mørkve; Dharmage, Shyamali C.; Janson, Christer; Abramson, Michael J.; Benediktsdóttir, Bryndís; Malinovschi, Andrei; Skulstad, Svein Magne; Bertelsen, Randi Jacobsen; Gómez Real, Francisco; Schlünssen, Vivi; Jõgi, Nils Oskar; Sánchez-Ramos, José Luis; Holm, Mathias; García Aymerich, Judith; Forsberg, Bertil; Svanes, Cecilie; Johannessen, Ane (Public Library of Science (PLoS), 2020)

  Emerging evidence suggests that parents' preconception exposures may influence offspring health. We aimed to investigate maternal and paternal smoking onset in specific time windows in relation to offspring body mass index ...
• Walking-related digital mobility outcomes as clinical trial endpoint measures: protocol for a scoping review

  Polhemus, Ashley Marie; Bosch de Basea i Gómez, Magda, 1982-; Delgado Ortiz, Laura; García Aymerich, Judith; Koch, Sarah; Frei, Anja (BMJ Publishing Group, 2020)

  Introduction: Advances in wearable sensor technology now enable frequent, objective monitoring of real-world walking. Walking-related digital mobility outcomes (DMOs), such as real-world walking speed, have the potential ...
• Physical activity and lung function-Cause or consequence?

  Bédard, Annabelle, 1986-; Carsin, Anne-Elie; Fuertes, Elaine; Accordini, Simone; Dharmage, Shyamali C.; Garcia Larsen, Vanessa; Heinrich, Joachim; Janson, Christer; Johannessen, Ane; Leynaert, Bénédicte; Sánchez-Ramos, José Luis; Peralta, Gabriela P.; Pin, Isabelle; Squillacioti, Giulia; Weyler, Joost; Jarvis, Deborah; García Aymerich, Judith (Public Library of Science (PLoS), 2020)

  Concerns exist that the positive association of physical activity with better lung function, which has been suggested in previous longitudinal studies in smokers, is due to reverse causation. To investigate this, we applied ...
• Toward a regulatory qualification of real-world mobility performance biomarkers in parkinson's patients using digital mobility outcomes

  Viceconti, Marco; Hernández Penna, Sabina; Dartee, Wilhelmus; Mazzà, Claudia; Caulfield, Brian; Becker, Clemens; Maetzler, Walter; García Aymerich, Judith; Davico, Giorgio; Rochester, Lynn (MDPI, 2020)

  Wearable inertial sensors can be used to monitor mobility in real-world settings over extended periods. Although these technologies are widely used in human movement research, they have not yet been qualified by drug ...
• Physical-activity trajectories during childhood and lung function at 15 years: findings from the ALSPAC cohort

  Roda, Célina; Mahmoud, Osama; Peralta, Gabriela P.; Fuertes, Elaine; Granell, Raquel; Serra, Ignasi; Henderson, John; Jarvis, Deborah; García Aymerich, Judith (Oxford University Press, 2020)

  Background: Although physical activity has many known health benefits, its association with lung function in childhood/adolescence remains unclear. We examined the association of physical-activity trajectories between 11 ...
• Acoustic and prosodic information for home monitoring of bipolar disorder

  Farrús, Mireia; Codina Filbà, Joan; Escudero, Joan (SAGE Publications, 2021)

  Epidemiological studies suggest that bipolar disorder has a prevalence of about 1% in European countries, becoming one of the most disabling illnesses in working age adults, and often long-term and persistent with complex ...
• Uncovering the spatiotemporal scales of common neuro-mental constructs

  Vila Vidal, Manel; Capouskova, Katerina; Atasoy, Selen; Kringelbach, Morten L.; Deco, Gustavo (Elsevier, 2020)
• Segmentation of the placenta and its vascular tree in Doppler ultrasound for fetal surgery planning

  Perera Bel, Enric; Ceresa, Mario; Torrents Barrena, Jordina; Masoller, Narcís; Valenzuela Alcaraz, Brenda; Gratacós Solsona, Eduard; Eixarch, Elisenda; González Ballester, Miguel Ángel, 1973- (Springer, 2020)

  Purpose Twin-to-twin transfusion syndrome (TTTS) is a serious condition that occurs in about 10–15% of monochorionic twin pregnancies. In most instances, the blood flow is unevenly distributed throughout the placenta ...
• The Dynamics of functional brain networks associated with depressive symptoms in a nonclinical sample

  Alonso Martínez, Sonsoles; Deco, Gustavo; ter Horst, Gert J.; Cabral, Joana (Frontiers, 2020)

  Brain function depends on the flexible and dynamic coordination of functional subsystems within distributed neural networks operating on multiple scales. Recent progress has been made in the characterization of functional ...
• Statistical learning in domestic chicks is modulated by strain and sex

  Santolin, Chiara; Rosa Salva, Orsola; Lemaire, Bastien S.; Regolin, Lucia; Vallortigara, Giorgio (Nature Research, 2020)

  Statistical learning is a key mechanism for detecting regularities from a variety of sensory inputs. Precocial newborn domestic chicks provide an excellent model for (1) exploring unsupervised forms of statistical learning ...
• Integration of artificial intelligence into clinical patient management: focus on cardiac imaging

  Loncaric, Filip; Camara, Oscar; Piella Fenoy, Gemma; Bijnens, Bart (Elsevier, 2020)

  Cardiac imaging is a crucial component in the management of patients with heart disease, and as such it influences multiple, inter-related parts of the clinical workflow: physician-patient contact, image acquisition, image ...
• Generation of induced pluripotent stem cells (iPSCs) by retroviral transduction of skin fibroblasts from four patients suffering Williams-Beuren syndrome (7q11.23 deletion)

  Kuebler, Bernd; Aran, Begoña; Flores Peirats, Raquel; Pérez Jurado, Luis Alberto; Veiga, Anna; Corominas, Roser; Cuscó Martí, Ivon, 1973- (Elsevier, 2020)

  Skin fibroblasts were obtained from four patients with Williams-Beuren syndrome (WBS) carrying the typical 1.5 Mb or 1.8 Mb deletion at the 7q11.23 genomic region. Induced pluripotent stem cells (iPSCs) were generated by ...
• [Review of:] Market manipulation and insider trading

  Mélon, Lela (CMP Publishing, 2020)
• Visual-reward driven changes of movement during action execution

  Marti Marca, Angela; Deco, Gustavo; Cos, Ignasi (Nature Research, 2020)

  Motor decision-making is often described as a sequential process, beginning with the assessment of available options and leading to the execution of a selected movement. While this view is likely to be accurate for decisions ...
• Derivation of induced pluripotent stem cells (iPSCs) by retroviral transduction of skin fibroblasts from four patients suffering 7q11.23 microduplication syndrome

  Kuebler, Bernd; Aran, Begoña; Flores Peirats, Raquel; Pérez Jurado, Luis Alberto; Veiga, Anna; Cuscó Martí, Ivon, 1973-; Corominas, Roser (Elsevier, 2020)

  Skin fibroblasts were obtained from four patients with 7q11.23 microduplication syndrome carrying the reciprocal rearrangement of Williams-Beuren syndrome at the 7q11.23 genomic region. Induced pluripotent stem cells (iPSCs) ...

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