• Self-consistency test reveals systematic bias in programs for prediction change of stability upon mutation

  Usmanova, Dinara R.; Bogatyreva, Natalya S.; Ariño Bernad, Joan; Eremina, Aleksandra A.; Gorshkova, Anastasiya A.; Kanevskiy, German M.; Lonishin, Lyubov R.; Meister, Alexander V.; Yakupova, Alisa G.; Kondrashov, Fyodor A., 1979-; Ivankov, Dmitry N. (Oxford University Press, 2018)

  Motivation: Computational prediction of the effect of mutations on protein stability is used by researchers in many fields. The utility of the prediction methods is affected by their accuracy and bias. Bias, a systematic ...
• Mapping by observation: building a user-tailored conducting system from spontaneous movements

  Sarasúa, Álvaro; Urbano, Julián; Gómez Gutiérrez, Emilia, 1975- (Frontiers, 2019)

  Metaphors are commonly used in interface design within Human-Computer Interaction (HCI). Interface metaphors provide users with a way to interact with the computer that resembles a known activity, giving instantaneous ...
• Evaluation of a sound quality visual feedback system for bow learning technique in violin beginners: an EEG study

  Blanco, Angel David; Ramírez, Rafael (Frontiers, 2019)

  Current music technologies can assist in the process of learning to play a musical instrument and provide objective measures for evaluating the improvement of music students in concrete music tasks. In this paper, we ...
• A distributional study of negated adjectives and antonyms

  Aina, Laura; Bernardi, Raffaella; Fernández, Raquel (CEUR Workshop Proceedings, 2018)

  In this paper, we investigate the relation between negated adjectives and antonyms in English using Distributional Semantics methods. Results show that, on the basis of contexts of use, a negated adjective (e.g., not cold) ...
• Color-matching shots from different cameras having unknown gamma or logarithmic encoding curves

  Gil Rodríguez, Raquel; Vazquez-Corral, Javier; Bertalmío, Marcelo (Society of Motion Picture & Television Engineers (SMPTE), 2017)

  In cinema and TV it is quite usual to have to work with footage coming from several cameras, which show noticeable color differences among them even if they are all the same model. In TV broadcasts, technicians work in ...
• Automatic, fast and perceptually accurate gamut mapping based on vision science models

  Zamir, Syed Waqas; Vazquez-Corral, Javier; Bertalmío, Marcelo (Society of Motion Picture & Television Engineers (SMPTE), 2017)

  Gamut mapping transforms colors of the original (image or video) content to the color palette of the display device with the simultaneous goals of (a) reproducing content accurately while preserving the artistic intent ...
• Searching for plans with carefully designed probes

  Lipovetzky, Nir; Geffner, Héctor (Association for the Advancement of Artificial Intelligence (AAAI), 2011)

  We define a probe to be a single action sequence computedgreedily from a given state that either terminates in the goalor fails. We show that by designing these probes carefullyusing a number of existing and new polynomial ...
• Derivatives and inverse of cascaded linear + nonlinear neural models

  Martínez García, Marina; Cyriac, Praveen; Batard, Thomas; Bertalmío, Marcelo; Malo, Jesús (Public Library of Science (PLoS), 2018)

  In vision science, cascades of Linear+Nonlinear transforms are very successful in modeling a number of perceptual experiences. However, the conventional literature is usually too focused on only describing the forward ...
• A geometric model of brightness perception and its application to color images correction

  Batard, Thomas; Bertalmío, Marcelo (Springer, 2018)

  Human perception involves many features like contours, shapes, textures, and colors to name a few. Whereas several geometric models for contours, shapes and textures perception have been proposed, the geometry of color ...
• Statistics of natural images as a function of dynamic range

  Grimaldi, Antoine Vincent; Kane, David; Bertalmío, Marcelo (Association for Research in Vision and Ophthalmology (ARVO), 2019)

  The statistics of real world images have been extensively investigated, but in virtually all cases using only low dynamic range image databases. The few studies that have considered high dynamic range (HDR) images ...
• In praise of artifice reloaded: caution with natural image databases in modeling vision

  Martínez García, Marina; Bertalmío, Marcelo; Malo, Jesús (Frontiers, 2019)

  Subjective image quality databases are a major source of raw data on how the visual system works in naturalistic environments. These databases describe the sensitivity of many observers to a wide range of distortions of ...
• End-to-end sound source separation conditioned on instrument labels

  Slizovskaia, Olga; Kim, Leo; Haro Ortega, Gloria; Gómez Gutiérrez, Emilia, 1975- (Institute of Electrical and Electronics Engineers (IEEE), 2019)

  Can we perform an end-to-end music source separation with a variable number of sources using a deep learning model? This paper presents an extension of the Wave-UNet [1] model which allows end-to-end monaural ...
• Effectiveness of the physical activity intervention program in the PREDIMED-Plus study: a randomized controlled trial

  Schröder, Helmut, 1958-; Cárdenas, Gabriela; Cárdenas, Gabriela; Cárdenas, Gabriela; Goday Arno, Alberto; Salas-Salvadó, Jordi; REDIMED-Plus investigators (BioMed Central, 2018)

  BACKGROUND: The development and implementation of effective physical activity (PA) intervention programs is challenging, particularly in older adults. After the first year of the intervention program used in the ongoing ...
• Diastolic dysfunction and exercise capacity in patients with metabolic syndrome and overweight/obesity

  Alonso-Gómez, A.; Tojal Sierra, Lucas; Fortuny Fraub, Elena; Goicolea Güemeza, Leire; Aboitiz Uribarria, Ane; Portillo, María P.; Toledo, Estefania; Schröder, Helmut, 1958-; Salas Salvadó, Jordi; Arós, Fernando (Elsevier, 2018)

  BACKGROUND: Left ventricle diastolic dysfunction (LVDD) is a common finding in high risk individuals, its presence being associated with reduced exercise capacity (EC). We assessed the prevalence of LVDD, applying the 2016 ...
• Single cell RNA-seq identifies the origins of heterogeneity in efficient cell transdifferentiation and reprogramming

  Francesconi, Mirko; Di Stefano, Bruno, 1984-; Berenguer, Clara; de Andrés-Aguayo, Luisa; Plana-Carmona, Marcos; Mendez-Lago, Maria; Guillaumet-Adkins, Amy; Rodríguez Esteban, Gustavo; Gut, Marta; Gut, Ivo Glynne; Heyn, Holger; Lehner, Ben, 1978-; Graf, T. (Thomas) (eLife, 2019)

  Forced transcription factor expression can transdifferentiate somatic cells into other specialised cell types or reprogram them into induced pluripotent stem cells (iPSCs) with variable efficiency. To better understand the ...
• Polycomb complexes in normal and malignant hematopoiesis

  Di Carlo, Valerio; Mocavini, Ivano; Di Croce, Luciano (Rockefeller University Press, 2019)

  Epigenetic mechanisms are crucial for sustaining cell type-specific transcription programs. Among the distinct factors, Polycomb group (PcG) proteins are major negative regulators of gene expression in mammals. These ...
• Occupational exposures and 20-year incidence of COPD: the European Community Respiratory Health Survey

  Lytras, Theodoros, 1987-; Kogevinas, Manolis; Carsin, Anne-Elie; Antó i Boqué, Josep Maria; García Aymerich, Judith; Zock, Jan-Paul (BMJ Publishing Group, 2018)

  Background: Occupational exposures have been associated with an increased risk of COPD. However, few studies have related objectively assessed occupational exposures to prospectively assessed incidence of COPD, using ...
• DNA methylation in childhood asthma: an epigenome-wide meta-analysis

  Xu, Chengjian; Bustamante Pineda, Mariona; García Aymerich, Judith; Antó i Boqué, Josep Maria; Sunyer Deu, Jordi; Koppelman, Gerard H. (Elsevier, 2018)

  Background: DNA methylation profiles associated with childhood asthma might provide novel insights into disease pathogenesis. We did an epigenome-wide association study to assess methylation profiles associated with childhood ...
• Differentiating resting brain states using ordinal symbolic analysis

  Quintero-Quiroz, Carlos; Montesano, Luis; Pons, Antonio J.; Torrent, Maria Carme; García Ojalvo, Jordi; Masoller, Cristina (American Institute of Physics (AIP), 2018)

  Symbolic methods of analysis are valuable tools for investigating complex time-dependent signals. In particular, the ordinal method defines sequences of symbols according to the ordering in which values appear in a time ...
• Simulations meet machine learning in structural biology

  Pérez, Adrià; Martínez Rosell, Gerard; De Fabritiis, Gianni (Elsevier, 2018)

  Classical molecular dynamics (MD) simulations will be able to reach sampling in the second timescale within five years, producing petabytes of simulation data at current force field accuracy. Notwithstanding this, MD will ...

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