• Restricted T cell receptor repertoire in CLL-like monoclonal B cell lymphocytosis and early stage CLL

  Blanco Ares, Gonzalo, 1989-; Vardi, Anna; Puiggros Metje, Anna Maria; Gómez-Llonín, Andrea; Muro, Manuel; Rodríguez-Rivera, María; Stalika, Evangelia; Abella Monreal, Eugenia; Gimeno Vázquez, Eva; López-Sánchez, Manuela; Senín, Alicia; Calvo, Xavier; Abrisqueta, Pau; Bosch José, Francesc Xavier, 1947-; Ferrer Del Alamo, Ana; Stamatopoulos, Kostas; Espinet Solà, Blanca (Taylor & Francis, 2018)

  Analysis of the T cell receptor (TR) repertoire of chronic lymphocytic leukemia-like monoclonal B cell lymphocytosis (CLL-like MBL) and early stage CLL is relevant for understanding the dynamic interaction of expanded B ...
• Seafood consumption, omega-3 fatty acids intake, and life-time prevalence of depression in the PREDIMED-Plus trial

  Sánchez Villegas, Almudena; Zomeño Fajardo, Maria Dolores; Fitó Colomer, Montserrat (MDPI, 2018)

  BACKGROUND: The aim of this analysis was to ascertain the type of relationship between fish and seafood consumption, omega-3 polyunsaturated fatty acids (ω-3 PUFA) intake, and depression prevalence. METHODS: Cross-sectional ...
• Dietary intake in population with metabolic syndrome: is the prevalence of inadequate intake influenced by geographical area? cross-sectional analysis from PREDIMED-Plus Study

  Cano-Ibáñez, Naomi; Zomeño Fajardo, Maria Dolores; Fitó Colomer, Montserrat; Gea, A. (MDPI, 2018)

  Inadequate diet influences chronic diseases such as cardiovascular disease (CVD), the leading cause of death in Spain. CVD figures vary from one geographical region to another; this could be associated with different food ...
• Transcriptional diversity during lineage commitment of human blood progenitors

  Chen, Lu; Breschi, Alessandra, 1988-; Guigó Serra, Roderic; Palumbo, Emilio; Rendon, Augusto (American Association for the Advancement of Science (AAAS), 2014)

  Blood cells derive from hematopoietic stem cells through stepwise fating events. To characterize gene expression programs driving lineage choice, we sequenced RNA from eight primary human hematopoietic progenitor populations ...
• Absence of canonical marks of active chromatin in developmentally regulated genes

  Pérez-Lluch, Sílvia; Blanco, Enrique; Tilgner, Hagen, 1980-; Curado, Joao; Ruiz-Romero, Marina; Corominas Guiu, Montserrat; Guigó Serra, Roderic (Nature Research, 2015)

  The interplay of active and repressive histone modifications is assumed to have a key role in the regulation of gene expression. In contrast to this generally accepted view, we show that the transcription of genes temporally ...
• Advances in allergen-microarray technology for diagnosis and monitoring of allergy: The MeDALL allergen-chip

  Lupinek, Christian; Antó i Boqué, Josep Maria; Valenta, Rudolf (Elsevier, 2013)

  Allergy diagnosis based on purified allergen molecules provides detailed information regarding the individual sensitization profile of allergic patients, allows monitoring of the development of allergic disease and of the ...
• Tracking five millennia of horse management with extensive ancient genome time series

  Fages, Antoine; Kuderna, Lukas F.K.; Marquès i Bonet, Tomàs, 1975-; Serres Armero, Aitor; Orlando, Ludovic (Elsevier, 2019)

  Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time series for a non-human organism to date, including genome-scale ...
• Determining protein structures using deep mutagenesis

  Schmiedel, Jörn M.; Lehner, Ben, 1978- (Nature Research, 2019)

  Determining the three-dimensional structures of macromolecules is a major goal of biological research, because of the close relationship between structure and function; however, thousands of protein domains still have ...
• Strategies for integrated analysis in imaging genetics studies

  Vilor Tejedor, Natàlia, 1988-; Alemany, Silvia; Cáceres, Alejandro; Bustamante Pineda, Mariona; Pujol Martí, Jesús, 1981-; Sunyer Deu, Jordi; González Ruiz, Juan Ramón (Elsevier, 2018)

  Imaging Genetics (IG) integrates neuroimaging and genomic data from the same individual, deepening our knowledge of the biological mechanisms behind neurodevelopmental domains and neurological disorders. Although the ...
• Effect of specific over nonspecific VR-based rehabilitation on poststroke motor recovery: a systematic meta-analysis

  Maier, Martina; Rubio Ballester, Belén; Duff, Armin; Duarte Oller, Esther; Verschure, Paul F.M.J. (SAGE Publications, 2019)

  BACKGROUND: Despite the rise of virtual reality (VR)-based interventions in stroke rehabilitation over the past decade, no consensus has been reached on its efficacy. This ostensibly puzzling outcome might not be that ...
• A review of automatic rhythm description systems

  Gouyon, Fabien; Dixon, Simon (MIT Press, 2005)

  Rhythm belongs with harmony, melody and timbre as one of the most fundamental aspects of music. Sound by its very nature is temporal, and in its most generic sense, the word \textit{rhythm} is used to refer to all of the ...
• Inferring directed networks using a rank-based connectivity measure

  Leguia, Marc G.; Martínez, Cristina G. B.; Malvestio, Irene; Tauste Campo, Adrià; Rocamora, Rodrigo; Levnajić, Zoran; Andrzejak, Ralph Gregor (American Physical Society, 2019)

  Inferring the topology of a network using the knowledge of the signals of each of the interacting units is key to understanding real-world systems. One way to address this problem is using data- driven methods like ...
• What do your eyes reveal about your foreign language? Reading emotional sentences in a native and foreign language

  Iacozza, Sara; Costa, Albert, 1970-; Duñabeitia, Jon Andoni (Public Library of Science (PLoS), 2017)

  Foreign languages are often learned in emotionally neutral academic environments which differ greatly from the familiar context where native languages are acquired. This difference in learning contexts has been argued to ...
• Causal inference and explaining away in a spiking network

  Moreno Bote, Rubén; Drugowitsch, Jan (Nature Research, 2015)

  While the brain uses spiking neurons for communication, theoretical research on brain computations has mostly focused on non-spiking networks. The nature of spike-based algorithms that achieve complex computations, such ...
• Probabilistic functional tractography of the human cortex revisited

  Trebaul, Lena; Rocamora Zúñiga, Rodrigo Alberto; David, Olivier (Elsevier, 2018)

  In patients with pharmaco-resistant focal epilepsies investigated with intracranial electroencephalography (iEEG), direct electrical stimulations of a cortical region induce cortico-cortical evoked potentials (CCEP) in ...
• Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set

  Del Toro, N.; Piñero González, Janet, 1977-; Furlong, Laura I., 1971-; Porras, P.; IMEx Consortium Curators (Nature Research, 2019)

  The current wealth of genomic variation data identified at nucleotide level presents the challenge of understanding by which mechanisms amino acid variation affects cellular processes. These effects may manifest as distinct ...
• Consonance processing in the absence of relevant experience: evidence from nonhuman animals

  Toro Soto, Juan Manuel, 1976-; Crespo Bojorque, Paola, 1985- (The Comparative Cognition Society, 2017)

  Consonance is a major feature in harmonic music that has been related to how pleasant a sound is perceived. Consonant chords are defined by simple frequency ratios between their composing tones, whereas dissonant chords ...
• Cognitive performance in healthy older adults relates to spontaneous switching between states of functional connectivity during rest

  Cabral, Joana R. B.; Vidaurre, Diego; Marques, Paulo; Magalhães, Ricardo; Moreira, Pedro Silva; Soares, José Miguel; Deco, Gustavo; Sousa, Nuno; Kringelbach, Morten L. (Nature Research, 2017)

  Growing evidence has shown that brain activity at rest slowly wanders through a repertoire of different states, where whole-brain functional connectivity (FC) temporarily settles into distinct FC patterns. Nevertheless, ...
• Spatial gamut mapping among non-inclusive gamuts

  Bertalmío, Marcelo; Vazquez-Corral, Javier (Elsevier, 2018)

  Gamut mapping transforms the color gamut of an image to that of a target device. Two cases are usually considered: gamut reduction (target gamut smaller than source gamut), and gamut extension (target gamut larger than ...
• Germline variation at 8q24 and prostate cancer risk in men of European ancestry

  Matejcic, Marco; Kogevinas, Manolis; Haiman, Christopher A. (Nature Research, 2018)

  Chromosome 8q24 is a susceptibility locus for multiple cancers, including prostate cancer. Here we combine genetic data across the 8q24 susceptibility region from 71,535 prostate cancer cases and 52,935 controls of European ...

View more