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Documents OpenAIRE (Open Access Infrastructure for Research in Europe)
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Publicacions finançades pel Framework Programme 7 o l'European Research Council de la Unió Europea en el marc del Projecte OpenAIRE (Open Access Infraestructure for Research in Europe) que promou l'accés obert a Europa.
Recent Submissions
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(Oxford University Press, 2020)Transposon sequencing is commonly applied for identifying the minimal set of genes required for cellular life; a major challenge in fields such as evolutionary or synthetic biology. However, the scientific community has ...
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(Nature Research, 2020)Calcium (Ca2+) influx into mitochondria occurs through a Ca2+-selective uniporter channel, which regulates essential cellular processes in eukaryotic organisms. Previous evolutionary analyses of its pore-forming subunits ...
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(Oxford University Press, 2020)Background: Hi-C experiments couple DNA-DNA proximity with next-generation sequencing to yield an unbiased description of genome-wide interactions. Previous methods describing Hi-C experiments have focused on the ...
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(2020)Tagging a musical excerpt with an emotion label may result in a vague and ambivalent exercise. This subjectivity entangles several high-level music description tasks when the computational models built to address them ...
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(Elsevier, 2020)Lifelong bilingualism may contribute to cognitive reserve (CR) in neurodegenerative diseases as shown by a delay of the age at symptom onset in bilinguals with Alzheimer’s disease (AD) and Mild Cognitive Impairment (MCI). ...
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(Cold Spring Harbor Laboratory Press (CSHL Press), 2020)Multiple myeloma (MM) is a plasma cell neoplasm associated with a broad variety of genetic lesions. In spite of this genetic heterogeneity, MMs share a characteristic malignant phenotype whose underlying molecular basis ...
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(BioMed Central, 2020)Deep mutational scanning (DMS) enables multiplexed measurement of the effects of thousands of variants of proteins, RNAs, and regulatory elements. Here, we present a customizable pipeline, DiMSum, that represents an ...
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(Elsevier, 2020)During thymic development and upon peripheral activation, T cells undergo extensive phenotypic and functional changes coordinated by lineage-specific developmental programs. To characterize the regulatory landscape controlling ...
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(BioMed Central, 2020)Background: The adverse health effects of early life exposure to tobacco smoking have been widely reported. In spite of this, the underlying molecular mechanisms of in utero and postnatal exposure to tobacco smoke are only ...
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(Portland Press, 2020)Interactions between proteins and RNA are at the base of numerous cellular regulatory and functional phenomena. The investigation of the biological relevance of non-coding RNAs has led to the identification of numerous ...
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(Springer, 2020)Background: Behr syndrome is a clinically distinct, but genetically heterogeneous disorder characterized by optic atrophy, progressive spastic paraparesis, and motor neuropathy often associated with ataxia. The molecular ...
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(SpringerOpen, 2020)Autoinflammatory diseases (AIDs) were first described as clinical disorders characterized by recurrent episodes of seemingly unprovoked sterile inflammation. In the past few years, the identification of novel AIDs expanded ...
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(Springer, 2017)In a sense, a two-party protocol achieves fairness if the output from the computation is obtained simultaneously by both parties. A seminal result by Cleve (STOC 1986) states that fairness is impossible, in general. ...
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(Elsevier, 2020)Objective: Current research does not provide a clear explanation for why some patients with Parkinson's Disease (PD) develop psychotic symptoms. The 'aberrant salience hypothesis' of psychosis has been influential and ...
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(Elsevier, 2020)
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(Nature Research, 2020)Attention-deficit/hyperactivity disorder (ADHD) is an impairing neurodevelopmental condition highly prevalent in current populations. Several hypotheses have been proposed to explain this paradox, mainly in the context of ...
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(Nature Research, 2020)Chromosome structure is a crucial regulatory factor for a wide range of nuclear processes. Chromosome conformation capture (3C)-based experiments combined with computational modelling are pivotal for unveiling 3D chromosome ...
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(Nature Research, 2020)The evolution of winged insects revolutionized terrestrial ecosystems and led to the largest animal radiation on Earth. However, we still have an incomplete picture of the genomic changes that underlay this diversification. ...
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(2020)Chromatic adaptation considering competing influences from emissive displays and ambient illumination is a little studied topic in the context of color management in proportion to its influence on displayed image appearance. ...
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(Elsevier, 2020)Mitochondrial DNA (mtDNA)-related diseases often pose a diagnostic challenge and require rigorous clinical and laboratory investigation. Pathogenic variants in the mitochondrial tRNA gene MT-TY, which encodes the tRNATyr, ...
