• Non-experts or experts? Statistical analyses of MOS using DSIS method

  Sugito, Yasuko; Bertalmío, Marcelo (Institute of Electrical and Electronics Engineers (IEEE), 2020)

  In image quality assessments, the results of subjective evaluation experiments that use the double-stimulus impairment scale (DSIS) method are often expressed in terms of the mean opinion score (MOS), which is the average ...
• Practical use suggests a re-evaluation of HDR objective quality metrics

  Sugito, Yasuko; Bertalmío, Marcelo (Institute of Electrical and Electronics Engineers (IEEE), 2019)

  Full-reference objective quality metrics for high dynamic range (HDR) images must be validated in terms of their consistency with subjective evaluation results, and previous studies have found a number of metrics that ...
• In-camera, photorealistic style transfer for on-set automatic grading

  Zabaleta, Itziar; Bertalmío, Marcelo (Society of Motion Picture and Television Engineers (SMPTE), 2018)

  In professional cinema, the intended artistic look of the movie informs the creation of a static 3D LUT that is applied on set, where further manual modifications to the image appearance are registered as 10-parameter ...
• HOTAIRM1 regulates neuronal differentiation by modulating NEUROGENIN 2 and the downstream neurogenic cascade

  Rea, Jessica; Menci, Valentina; Tollis, Paolo; Santini, Tiziana; Armaos, Alexandros, 1989-; Garone, Maria Giovanna; Iberite, Federica; Cipriano, Andrea; Tartaglia, Gian Gaetano; Rosa, Alessandro; Ballarino, Monica; Laneve, Pietro; Caffarelli, Elisa (Nature Research, 2020)

  Neuronal differentiation is a timely and spatially regulated process, relying on precisely orchestrated gene expression control. The sequential activation/repression of genes driving cell fate specification is achieved by ...
• Color stabilization for multi-camera light-field imaging

  Vu-Thanh, Olivier; Canham, Trevor; Vazquez-Corral, Javier; Gil Rodríguez, Raquel; Bertalmío, Marcelo (Institute of Electrical and Electronics Engineers (IEEE), 2020)

  By capturing a more complete rendition of scene light than standard 2D cameras, light-field technology represents an important step towards closing the gap between live action cinematography and computer graphics. Light-field ...
• Transcriptomic differences in MSA clinical variants

  Pérez Soriano, Alexandra; Arnal, Magdalena; Botta Orfila, Teresa; Giraldo, Darly; Fernández, Manel; Compta, Yaroslau; Fernández-Santiago, Ruben; Ezquerra, Mario; Tartaglia, Gian Gaetano; Martí, M. Josep; Catalan multiple system atrophy-registry (CMSAR) (Nature Research, 2020)

  Background: Multiple system atrophy (MSA) is a rare oligodendroglial synucleinopathy of unknown etiopathogenesis including two major clinical variants with predominant parkinsonism (MSA-P) or cerebellar dysfunction (MSA-C). ...
• Characterization of different alginate lyases for dissolving Pseudomonas aeruginosa biofilms

  Blanco Cabra, Núria; Paetzold, Bernhard, 1981-; Ferrar, Tony; Mazzolini, Rocco; Torrents, Eduard; Serrano Pubull, Luis, 1982-; Lluch-Senar, Maria 1982- (Nature Research, 2020)

  Aggregates of Pseudomonas aeruginosa form a protective barrier against antibiotics and the immune system. These barriers, known as biofilms, are associated with several infectious diseases. One of the main components of ...
• Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence

  Toda, Haruka; Borràs, Eva; Sabidó Aguadé, Eduard, 1981-; del Portillo, Hernando A. (Nature Research, 2020)

  Plasmodium vivax is the most widely distributed human malaria parasite. Previous studies have shown that circulating microparticles during P. vivax acute attacks are indirectly associated with severity. Extracellular ...
• The protective role of m1A during stress-induced granulation

  Alriquet, Marion; Calloni, Giulia; Martínez Limón, Adrián; Delli Ponti, Riccardo, 1987-; Hanspach, Gerd; Hegensbach, Martin; Tartaglia, Gian Gaetano; Vabulas, R. Martin (Oxford University Press (OUP), 2020)

  Post-transcriptional methylation of N6- and N1-adenine can effect transcriptome turnover and translation. Furthermore, the regulatory function of N6-methyladenine (m6A) during heat shock has been uncovered, including the ...
• Sampling time-dependent artifacts in single-cell genomics studies

  Massoni-Badosa, Ramon; Iacono, Giovanni; Moutinho, Catia; Kulis, Marta; Palau, Núria; Marchese, Domenica, 1986-; Rodríguez Ubreva, Javier; Ballestar, Esteban; Rodríguez Esteban, Gustavo; Marsal, Sara; Aymerich, Marta; Colomer, Dolors; Campo, Elias; Julià Cano, Antoni; Martín-Subero, José I.; Heyn, Holger (BioMed Central, 2020)

  Robust protocols and automation now enable large-scale single-cell RNA and ATAC sequencing experiments and their application on biobank and clinical cohorts. However, technical biases introduced during sample acquisition ...
• Integrative omics analysis reveals a limited transcriptional shock after yeast interspecies hybridization

  Hovhannisyan, Hrant; Saus Martínez, Ester; Ksiezopolska, Ewa; Roberts, Alex J. Hinks; Louis, Edward J.; Gabaldón Estevan, Juan Antonio (Frontiers Media, 2020)

  The formation of interspecific hybrids results in the coexistence of two diverged genomes within the same nucleus. It has been hypothesized that negative epistatic interactions and regulatory interferences between the two ...
• Caenorhabditis elegans processes sensory information to choose between freeloading and self-defense strategies

  Schiffer, Jodie A.; Servello, Francesco A.; Heath, William R.; Amrit, Francis Raj Ghandi; Stumbur, Stephanie V; Eder, Matthias; Martin, Olivier M. F.; Johnsen, Sean B.; Stanley, Julia A.; Tam, Hannah; Brennan, Sara J.; McGowan, Natalie G.; Vogelaar, Abigail L.; Xu, Yuyan; Serkin, William T.; Ghazi, Arjumand; Stroustrup, Nicholas; Apfeld, Javier (eLife, 2020)

  Hydrogen peroxide is the preeminent chemical weapon that organisms use for combat. Individual cells rely on conserved defenses to prevent and repair peroxide-induced damage, but whether similar defenses might be coordinated ...
• Inferring active metabolic pathways from proteomics and essentiality data

  Montero-Blay, Ariadna; Piñero-Lambea, Carlos; Miravet Verde, Samuel; Lluch-Senar, Maria 1982-; Serrano Pubull, Luis, 1982- (Elsevier, 2020)

  Here, we propose an approach to identify active metabolic pathways by integrating gene essentiality analysis and protein abundance. We use two bacterial species (Mycoplasma pneumoniae and Mycoplasma agalactiae) that share ...
• Modeling the formation of social conventions from embodied real-time interactions

  Freire, Ismael T.; Moulin-Frier, Clement; Sánchez Fibla, Martí; Arsiwalla, Xerxes D.; Verschure, Paul F. M. J. (Public Library of Science (PLoS), 2020)

  What is the role of real-time control and learning in the formation of social conventions? To answer this question, we propose a computational model that matches human behavioral data in a social decision-making game that ...
• Amyloid beta, tau, synaptic, neurodegeneration, and glial biomarkers in the preclinical stage of the Alzheimer's continuum

  Milà Alomà, Marta; Salvadó, Gemma; Gispert López, Juan Domingo; Vilor Tejedor, Natàlia, 1988-; Grau-Rivera, Oriol; Sala Vila, Aleix; Sánchez Benavides, Gonzalo; Arenaza Urquijo, Eider M.; Crous-Bou, Marta; González de Echávarri, José Maria; Minguillón, Carolina; Fauria, Karine; Simon, Maryline; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj; Suárez-Calvet, Marc; Molinuevo, José Luis; ALFA Study (Wiley, 2020)

  Introduction: The biological pathways involved in the preclinical stage of the Alzheimer's continuum are not well understood. Methods: We used NeuroToolKit and Elecsys® immunoassays to measure cerebrospinal fluid (CSF) ...
• Mycoplasma pneumoniae genome editing based on oligo recombineering and Cas9-mediated counterselection

  Piñero-Lambea, Carlos; García Ramallo, Eva; Martínez, Sira; Delgado, Javier; Serrano Pubull, Luis, 1982-; Lluch-Senar, Maria 1982- (American Chemical Society (ACS), 2020)

  Mycoplasma species share a set of features, such as lack of a cell wall, streamlined genomes, simplified metabolism, and the use of a deviant genetic code, that make them attractive approximations of what a chassis strain ...
• The Freesound Loop dataset and annotation tool

  Ramires, António; Font, Frederic; Bogdanov, Dmitry; Smith, Jordan B. L.; Yang, Yi-Hsuan; Ching, Joann; Chen, Bo-Yu; Wu, Yueh-Kao; Wei-Han, Hsu; Serra, Xavier (2020)

  Music loops are essential ingredients in electronic music production, and there is a high demand for pre-recorded loops in a variety of styles. Several commercial and community databases have been created to meet this ...
• Representation of foreseeable choice outcomes in orbitofrontal cortex triplet-wise interactions

  Balaguer-Ballester, Emili; Nogueira Mañas, Ramon; Abofalia, Juan M.; Moreno Bote, Rubén; Sanchez-Vives, Maria V. (Public Library of Science (PLoS), 2020)

  Shared neuronal variability has been shown to modulate cognitive processing. However, the relationship between shared variability and behavioral performance is heterogeneous and complex in frontal areas such as the ...
• Microtubule nucleation properties of single human γTuRCs explained by their Cryo-EM Structure

  Consolati, Tanja; Locke, Julia; Roostalu, Johanna; Chen, Zhuo Angel; Gannon, Julian; Asthana, Jayant; Lim, Wei Ming; Martino, Fabrizio; Cvetkovic, Milos A.; Rappsilber, Juri; Costa, Alessandro; Surrey, Thomas (Elsevier, 2020)

  The γ-tubulin ring complex (γTuRC) is the major microtubule nucleator in cells. The mechanism of its regulation is not understood. We purified human γTuRC and measured its nucleation properties in a total internal reflection ...
• Endogenous CRISPR/Cas9 arrays for scalable whole-organism lineage tracing

  Cotterell, James; Vila-Cejudo, Marta; Batlle Morera, Laura; Sharpe, James (Company of Biologists, 2020)

  The past decade has seen a renewed appreciation of the central importance of cellular lineages to many questions in biology (especially organogenesis, stem cells and tumor biology). This has been driven in part by a ...

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