• Diverse families of transposable elements affect the transcriptional regulation of stress-response genes in Drosophila melanogaster

  Villanueva Cañas, José Luis, 1984-; Horvath, Vivien; Aguilera, Laura; González, Josefa (Oxford University Press, 2019)

  Although transposable elements are an important source of regulatory variation, their genome-wide contribution to the transcriptional regulation of stress-response genes has not been studied yet. Stress is a major aspect ...
• CSF glial biomarkers YKL40 and sTREM2 are associated with longitudinal volume and diffusivity changes in cognitively unimpaired individuals

  Falcón, Carles; Monté-Rubio, Gemma C.; Grau-Rivera, Oriol; Suárez-Calvet, Marc; Sánchez Valle, Raquel; Rami, Lorena; Bosch, Beatriz; Haass, Christian; Gispert López, Juan Domingo; Molinuevo, José Luis (Elsevier, 2019)

  Cerebrospinal fluid (CSF) YKL40 and sTREM2 are astroglial and microglial activity biomarkers, respectively. We assessed whether CSF YKL40 and sTREM2 baseline levels are associated with longitudinal brain volume and diffusivity ...
• Association analyses identify 31 new risk loci for colorectal cancer susceptibility

  Law, Philip J.; The PRACTICAL consortium; Dunlop, Malcolm G. (Nature Research, 2019)

  Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide, and has a strong heritable basis. We report a genome-wide association analysis of 34,627 CRC cases and 71,379 controls of European ancestry that ...
• The complete mitogenome of the Eurasian blindsnake Xerotyphlops vermicularis (Reptilia, Typhlopidae)

  Kornilios, Panagiotis (Taylor & Francis, 2019)

  The Eurasian or Greek blindsnake, Xerotyphlops vermicularis, is the only European representative of the infraorder Scolecophidia, a largely understudied group of snakes with a poor record of available mitogenomes. Its ...
• Evolutionary and functional impact of common polymorphic inversions in the human genome

  Giner Delgado, Carla; Villatoro, Sergi; Lerga Jaso, Jon; Gayà Vidal, Magdalena; Oliva, Meritxell; Castellano Esteve, David; Pantano Rubiño, Lorena, 1982-; Bitarello, Bárbara D.; Izquierdo, David; Noguera, Isaac; Olalde Marquínez, Íñigo, 1987-; Delprat, Alejandra; Blancher, Antoine; Lalueza Fox, Carles, 1965-; Esko, Tõnu; O'Reilly, Paul F.; Andrés Morán, Aida, 1976-; Ferretti, Luca; Puig, Marta; Cáceres Aguilar, Mario (Nature Research, 2019)

  Inversions are one type of structural variants linked to phenotypic differences and adaptation in multiple organisms. However, there is still very little information about polymorphic inversions in the human genome due to ...
• A unique cluster of roo insertions in the promoter region of a stress response gene in Drosophila melanogaster

  Merenciano, Miriam; Iacometti, Camillo; González, Josefa (BioMed Central, 2019)

  Transposable elements (TEs) are not randomly distributed in the genome. A genome-wide analysis of the D. melanogaster genome found that differences in TE density across 50 kb genomic regions was due both to transposition ...
• A benchmark of transposon insertion detection tools using real data

  Vendrell Mir, Pol; Barteri, Fabio; Merenciano, Miriam; González, Josefa; Casacuberta, Josep M.; Castanera, Raúl (BioMed Central, 2019)

  Background: Transposable elements (TEs) are an important source of genomic variability in eukaryotic genomes. Their activity impacts genome architecture and gene expression and can lead to drastic phenotypic changes. ...
• From cognitive control to visual incongruity: conflict detection in surrealistic images

  Ruzzoli, Manuela; McGuinness, Aoife; Morís Fernández, Luis, 1982-; Soto-Faraco, Salvador, 1970- (Public Library of Science (PLoS), 2020)

  This study explored brain responses to images that exploit incongruity as a creative technique, often used in advertising (i.e., surrealistic images). We hypothesized that these images would reveal responses akin to cognitive ...
• Cortical-inspired Wilson–Cowan-type equations for orientation-dependent contrast perception modelling

  Bertalmío, Marcelo; Calatroni, Luca; Franceschi, Valentina; Franceschiello, Benedetta; Prandi, Dario (Springer, 2020)

  We consider the evolution model proposed in Bertalmío (Front Comput Neurosci 8:71, 2014), Bertalmío et al. (IEEE Trans Image Process 16(4):1058–1072, 2007) to describe illusory contrast perception phenomena induced by ...
• Association of occupational exposure to disinfectants with incidence of chronic obstructive pulmonary disease among US female nurses

  Dumas, Orianne; Varraso, Raphaëlle; Boggs, Krislyn M.; Quinot, Catherine; Zock, Jan-Paul; Henneberger, Paul K.; Speizer, Frank E.; Le Moual, Nicole; Camargo, Carlos A. (American Medical Association, 2019)

  Importance: Exposure to disinfectants in health care workers has been associated with respiratory health outcomes, including asthma. Despite the biological plausibility of an association between disinfectants (irritant ...
• Density of green spaces and cardiovascular risk factors in the city of Madrid: the heart healthy hoods study

  Plans, Elena; Gullón, Pedro; Cebrecos, Alba; Fontán, Mario; Díez, Julia; Nieuwenhuijsen, Mark J.; Franco, Manuel (MDPI, 2019)

  The aim of this study is to evaluate the relationship between the density of green spaces at different buffer sizes (300, 500, 1000 and 1500 m) and cardiovascular risk factors (obesity, hypertension, high cholesterol, and ...
• Beer phenolic composition of simple phenols, prenylated flavonoids and alkylresorcinols

  Boronat Rigol, Anna, 1990-; Soldevila-Domenech, Natalia; Rodríguez-Morató, Jose, 1987-; Martínez-Huélamo, Miriam; Lamuela-Raventós, Rosa M.; Torre Fornell, Rafael de la (MDPI, 2020)

  Beer is a fermented beverage with beneficial phenolic compounds and is widely consumed worldwide. The current study aimed to describe the content of three families of phenolic compounds with relevant biological activities: ...
• Border rescue

  Oberman, Kieran (Cambridge University Press - Core, 2019)

  Every year, thousands of refugees and other migrants die trying to cross borders. The dangers are many. Migrants die from exhaustion crossing deserts, freeze on mountain passes, drown at sea. One way states can save lives ...
• Anticipating the financial crisis: evidence from insider trading in banks

  Akin, Özlem; Marín Vigueras, José María; Peydró, José-Luis (Oxford University Press, 2020)

  Banking crises are recurrent phenomena, often induced by excessive bank risk-taking, which may be due to behavioural reasons (over-optimistic banks neglecting risks) and to conflicts of interest between bank shareholders/managers ...
• Evolutionary and functional patterns of shared gene neighbourhood in fungi

  Marcet Houben, Marina; Gabaldón Estevan, Juan Antonio, 1973- (Nature Research, 2019)

  Gene clusters comprise genomically co-localized and potentially co-regulated genes that tend to be conserved across species. In eukaryotes, multiple examples of metabolic gene clusters are known, particularly among fungi ...
• Creating urban green infrastructure where it is needed - A spatial ecosystem service-based decision analysis of green roofs in Barcelona

  Langemeyer, Johannes; Wedgwood, Diego; McPhearson, Timon; Baró Porras, Francesc; Madsen, Anders L.; Barton, David N. (Elsevier, 2020)

  As cities face increasing pressure from densification trends, green roofs represent a valuable source of ecosystem services for residents of compact metropolises where available green space is scarce. However, to date ...
• The impact of e-procurement on institutional quality

  Mélon, Lela; Spruk, Rock (Emerald, 2020)

  We examine the contribution of e-procurement to the institutional quality. To this end, we exploit the early adoption of large-scale e-procurement platforms in three EU countries to consistently estimate the effect of ...
• Population health inequalities across and within european metropolitan areas through the lens of the EURO-HEALTHY Population Health Index

  Costa, Claudia; Santana, Paula; Dimitroulopoulou, Sani; Burström, Bo; Borrell i Thió, Carme; Schweikart, Jürgen; Dzúrová, Dagmar; Zangarini, Nicolás; Katsouyanni, Klea; Deboseree, Patrick; Freitas, Ângela; Mitsakou, Christina; Samoli, Evangelia; Vardoulakis, Sotiris; Marí Dell'Olmo, Marc, 1978-; Gotsens Miquel, Mercè, 1983-; Lustigova, Michala; Corman, Diana; Costa, Giuseppe (MDPI, 2019)

  The different geographical contexts seen in European metropolitan areas are reflected in the uneven distribution of health risk factors for the population. Accumulating evidence on multiple health determinants point to the ...
• Joseph Schumpeter Lecture: sharing a government

  Ventura, Jaume (Oxford University Press, 2019)

  This paper develops a simple theoretical framework to study a set of regions, each with its own regional government, who share a union or central government. These governments must decide whether to implement or discard a ...
• A theory of economic unions

  Gancia, Gino A.; Ponzetto, Giacomo A. M.; Ventura, Jaume (Elsevier, 2020)

  After decades of successful growth, economic unions have recently become the focus of heightened political controversy. To understand why, we develop a theoretical model of the effects on trade, income distribution and ...

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