Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study
Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study
Citació
- Costas L, Infante-Rivard C, Zock JP, Van Tongeren M, Boffetta P, Cusson A, et al. Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study. Br J Cancer. 2015 Mar;112(7):1251-6. DOI: 10.1038/bjc.2015.83
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Descripció
Resum
Background: Incidence rates of lymphoma are usually higher in men than in women, and oestrogens may protect against lymphoma. Methods: We evaluated occupational exposure to endocrine disrupting chemicals (EDCs) among 2457 controls and 2178 incident lymphoma cases and subtypes from the European Epilymph study. Results: Over 30 years of exposure to EDCs compared to no exposure was associated with a 24% increased risk of mature B-cell neoplasms (P-trend=0.02). Associations were observed among men, but not women. Conclusions: Prolonged occupational exposure to endocrine disruptors seems to be moderately associated with some lymphoma subtypes.Descripció
Includes supplemental materials for the online appendix.