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The influence of meal timing and residential artificial light-at-night in the development of non-communicable diseases

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dc.contributor.author Palomar Cros, Anna
dc.contributor.other Kogevinas, Manolis
dc.contributor.other Romaguera, Dora
dc.contributor.other Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida
dc.date.accessioned 2023-11-05T02:33:37Z
dc.date.available 2023-11-05T02:33:37Z
dc.date.issued 2022-11-04T13:36:36Z
dc.date.issued 2023-11-02T23:45:35Z
dc.date.issued 2022-11-02
dc.identifier http://hdl.handle.net/10803/675882
dc.identifier.uri http://hdl.handle.net/10230/54702
dc.description.abstract Les malalties no transmissibles (MNT) causen cada any 41 milions de morts en tot el món. Arran del descobriment del rellotge circadiari i dels efectes nocius del treball de nit continuat, s'ha enfocat molta atenció de la comunitat científica a estudiar l'alteració dels ritmes circadiaris i les seves conseqüències. Aquesta tesi aporta noves evidències que demostren que l'alteració d'aquest sistema, com a conseqüència (i) del retard dels àpats al llarg del dia i l'escurçament del període de dejuni nocturn i (ii) de l'exposició a llum artificial durant la nit en l'entorn urbà pot resultar en un augment del risc de desenvolupar MNT, com el càncer, la diabetis tipus 2 o les malalties cardiovasculars. Aquesta tesi subratlla la importància de menjar d'hora durant el dia, en combinació amb un dejuni nocturn perllongat, i de reduir la contaminació lumínica a l’entorn urbà per protegir el sistema circadiari i prevenir algunes MNT.
dc.description.abstract Non-communicable diseases (NCDs) cause 41 million deaths worldwide every year. Following the discovery of the circadian clock and the harmful effects of continuous night shift work, much attention from the scientific community has focused on studying the alteration of circadian rhythms and its consequences. This thesis provides new evidence showing that the alteration of this system, as a result of (i) the delay of daily meals and the shortening of the nighttime fasting period and (ii) the exposure to artificial light-at-night in the urban environment, can increase the risk of developing NCDs, such as cancer, type 2 diabetes or cardiovascular diseases. This thesis highlights the importance of eating early in the day, in combination with prolonged nighttime fasting, and reducing the levels of light pollution in the urban environment to protect the circadian system and to prevent the development of NCDs.
dc.description.abstract Programa de doctorat en Biomedicina
dc.format 316 p.
dc.format application/pdf
dc.format application/pdf
dc.language.iso eng
dc.publisher Universitat Pompeu Fabra
dc.rights L'accés als continguts d'aquesta tesi queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons: http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights info:eu-repo/semantics/openAccess
dc.source TDX (Tesis Doctorals en Xarxa)
dc.title The influence of meal timing and residential artificial light-at-night in the development of non-communicable diseases
dc.type info:eu-repo/semantics/doctoralThesis
dc.type info:eu-repo/semantics/publishedVersion
dc.date.modified 2023-11-02T23:45:35Z
dc.subject.keyword Meal timing
dc.subject.keyword Fasting
dc.subject.keyword Artificial light-at-night
dc.subject.keyword Circadian rhythms
dc.subject.keyword Non-communicable diseases
dc.subject.keyword Horari dels àpats
dc.subject.keyword Dejuni
dc.subject.keyword Llum artificial a la nit
dc.subject.keyword Ritmes circadiaris
dc.subject.keyword Malalties no transmissibles
dc.subject.keyword 577


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