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Analysis of co-ancestry links in modern and ancient human populations

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dc.contributor.author Ferrando-Bernal, Manuel, 1990-
dc.contributor.other manu.ferrandobernal@gmail.com
dc.contributor.other true
dc.contributor.other Lalueza Fox, Carles, 1965-
dc.contributor.other Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut.
dc.date.accessioned 2023-02-08T02:32:08Z
dc.date.available 2023-02-08T02:32:08Z
dc.date.issued 2021-09-27T16:11:41Z
dc.date.issued 2021-09-27T16:11:41Z
dc.date.issued 2021-07-09
dc.identifier http://hdl.handle.net/10803/672475
dc.identifier.uri http://hdl.handle.net/10230/48524
dc.description.abstract The aim of this thesis is to apply Identity by Descent (IBD) methodology to identify ancestry connections among individuals from genetically similar populations. Recombination events diminish the likelihood to detect IBDs. As most of the aDNA samples date from 2,000 years ago or more, this methodology has rarely been applied to these studies. In this thesis we detect IBD among modern individuals from similar Bantu populations and among modern Europeans with an historical individual (700 years ago) from the Iberian peninsula, which was sequenced to a high coverage. Our results show that IBDs can be used to detect the genomic structure in genetically close populations. For example, they can be used to show high degrees of endogamy caused by isolation or to identify ancestral connections among individuals belonging to different populations that otherwise would be difficult to see with other more commonly used methods.
dc.format 153 p.
dc.format application/pdf
dc.format application/pdf
dc.language.iso eng
dc.rights L'accés als continguts d'aquesta tesi queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons: http://creativecommons.org/licenses/by/4.0/
dc.rights info:eu-repo/semantics/openAccess
dc.source TDX (Tesis Doctorals en Xarxa)
dc.title Analysis of co-ancestry links in modern and ancient human populations
dc.type info:eu-repo/semantics/doctoralThesis
dc.type info:eu-repo/semantics/publishedVersion
dc.date.modified 2023-02-07T17:25:32Z
dc.subject.keyword Identity-by-Descent
dc.subject.keyword Endogamy
dc.subject.keyword Homocygosis
dc.subject.keyword Ancient DNA
dc.subject.keyword Networks Spanish
dc.subject.keyword Idéntico por descendencia
dc.subject.keyword Endogamia
dc.subject.keyword Homocigosis
dc.subject.keyword ADN antiguo
dc.subject.keyword Redes
dc.subject.keyword 575

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