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A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives

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dc.contributor.author Westbury, Michael V.
dc.contributor.author Barnett, Ross
dc.contributor.author Sandoval Velasco, Marcela
dc.contributor.author Gower, Graham
dc.contributor.author Garrett Vieira, Filipe
dc.contributor.author Manuel Montero, Marc de, 1991-
dc.contributor.author Hansen, Anders J.
dc.contributor.author Yamaguchi, Nobuyuki
dc.contributor.author Werdelin, Lars
dc.contributor.author Marquès i Bonet, Tomàs, 1975-
dc.contributor.author Gilbert, M Thomas
dc.contributor.author Lorenzen, Eline D.
dc.date.accessioned 2021-08-03T06:18:37Z
dc.date.available 2021-08-03T06:18:37Z
dc.date.issued 2021
dc.identifier.citation Westbury MV, Barnett R, Sandoval-Velasco M, Gower G, Garrett Vieira F, de Manuel M, Hansen AJ, Yamaguchi N, Werdelin L, Marquès Bonet T, Gilbert MTP, Lorenzen ED. A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives. Open Research Europe. 2021;1:25. DOI: 10.12688/openreseurope.13104.2
dc.identifier.issn 2732-5121
dc.identifier.uri http://hdl.handle.net/10230/48305
dc.description.abstract Background: The evolutionary relationships of Felidae during their Early–Middle Miocene radiation is contentious. Although the early common ancestors have been subsumed under the grade-group Pseudaelurus, this group is thought to be paraphyletic, including the early ancestors of both modern cats and extinct sabretooths. Methods: Here, we sequenced a draft nuclear genome of Smilodon populator, dated to 13,182 ± 90 cal BP, making this the oldest palaeogenome from South America to date, a region known to be problematic for ancient DNA preservation. We analysed this genome, together with genomes from other extinct and extant cats to investigate their phylogenetic relationships. Results: We confirm a deep divergence (~20.65 Ma) within sabre-toothed cats. Through the analysis of both simulated and empirical data, we show a lack of gene flow between Smilodon and contemporary Felidae. Conclusions: Given that some species traditionally assigned to Pseudaelurus originated in the Early Miocene ~20 Ma, this indicates that some species of Pseudaelurus may be younger than the lineages they purportedly gave rise to, further supporting the hypothesis that Pseudaelurus was paraphyletic.
dc.description.sponsorship This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No [681396]), (project Extinction Genomics). This project has also received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no. FP7-PEOPLE-2011-IEF-298820. The work was also supported by the Independent Research Fund Denmark | Natural Sciences, Forskningsprojekt 1, grant no. 8021-00218B to EDL.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher F1000 Research
dc.relation.ispartof Open Research Europe. 2021;1:25
dc.rights © 2021 Westbury MV et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.title A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.12688/openreseurope.13104.2
dc.subject.keyword Smilodon
dc.subject.keyword Ancient DNA
dc.subject.keyword Genomics
dc.subject.keyword Gene flow
dc.subject.keyword Felidae
dc.subject.keyword Palaeogenome
dc.subject.keyword Phylogeny
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/681396
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/298820
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion


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