• Novel insights in nicotine addiction : focus on cognitive function

  Saravia Santos, Rocio, 1988- (Universitat Pompeu Fabra, 2019-01-10)

  Cigarette smoking continues to be leading cause of preventable cause of death worldwide. Cognitive modulation by nicotine seems to be a key factor in nicotine addiction. Several studies indicate that initial nicotine intake ...
• Identification of genetic modifiers of penetrance in human inherited disease

  Puigdevall Costa, Pau, 1991- (Universitat Pompeu Fabra, 2019-01-17)

  Understanding the molecular basis of human inherited disease is a challenging task due to the complexity of mapping the genotype to the phenotype. The study of diseases running in families has shown that the inheritance ...
• Neurogenic bowel dysfunction in subjects with brain injury : prevalence, risk factors, clinical characterization and physiopathology

  Haya Hidalgo, Jenny Rosario, 1978- (Universitat Pompeu Fabra, 2018-12-19)

  To date, there are scarce data on bowel dysfunction (BD) in patients after brain injury (BI). Until now, only fecal incontinence (FI) has received attention and it has been mainly associated to patients’ age or performance ...
• Evaluación de la implementación a escala del plan de actividad física, deporte y salud

  González Viana, Angelina, 1974- (Universitat Pompeu Fabra, 2018-12-13)

  The control of proper progression of eukaryotic cell cycle is essential if cells want to continue proliferating appropriately, and it is a conserve feature from yeast to human cells. One of the most important points of ...
• Las cláusulas durmientes de integración latinoamericana: origen, función y alternativas para despertarlas

  Herrera, Juan C. (Universitat Pompeu Fabra, 2019-02-01)

  ¿Es la integración económica, política y social un mandato jurídico en Latinoamérica? ¿Es dicha integración una de las promesas centrales del derecho constitucional contemporáneo de la región? La respuesta rápida es: sí. ...
• Mediación cultural entre Bulgaria y el mundo hispánico: la circulación de las traducciones literarias y sus mediadores (1882-2012)

  Ikoff, Ventsislav (Universitat Pompeu Fabra, 2018-02-07)

  Esta tesis doctoral estudia la circulación de las traducciones literarias en formato libro entre Bulgaria y el mundo hispánico (España e Hispanoamérica) durante el periodo situado entre 1882 y 2012. La investigación se ...
• Post-transcriptional regulation by UNR : insights into histone mRNA metabolism and cellular senescence

  Inglés Ferrándiz, Marta, 1989- (Universitat Pompeu Fabra, 2018-12-14)

  In this thesis, we have been studying the role of UNR, and RNA-binding protein that regulates translation and/or stability of its targets. The functional relevance of UNR was studied in two different molecular contexts: ...
• Insights into the human demographic history of Africa through whole-genome sequence analysis

  Serra Vidal, Gerard, 1989- (Universitat Pompeu Fabra, 2018-12-05)

  Àfrica és l'origen de totes les poblacions humanes actuals, i malgrat contenir els nivells més elevats de diversitat genètica, la seva història demogràfica ha estat relativament poc estudiada, amb moltes preguntes rellevants ...
• Prenatal and postnatal exposure to tobacco smoking and molecular signatures in children

  Vives Usano, Marta, 1990- (Universitat Pompeu Fabra, 2018-11-26)

  Maternal smoking during pregnancy (MSDP) and postnatal secondhand smoking (SHS) are ongoing public health concerns that are associated with adverse child health outcomes, but not much is known about the molecular mechanisms. ...
• Alternative mechanisms of gene regulation during hematopoiesis

  Ullrich, Sebastian, 1984- (Universitat Pompeu Fabra, 2018-12-19)

  Gene regulation orchestrates the development of different cell types and organs from the same genetic blueprint. While the basic mode of gene regulation is driven by transcription factors, there are a variety of other ...
• A Comprehensive multiomics approach towards understanding obsessive-compulsive disorder

  Domènech Salgado, Laura, 1989- (Universitat Pompeu Fabra, 2018-12-20)

  To date, very little progress has been made towards elucidating the genetic causes of obsessive-compulsive disorder (OCD). In this project we have performed rare variant association study (RVAS) transcriptomics and ...
• Role and therapeutic potential of the endocannabinoid system in animal models of intellectual disability

  Navarro Romero, Alba, 1990- (Universitat Pompeu Fabra, 2018-11-27)

  Intellectual disability encompasses several neurodevelopmental disorders characterized by impairments in cognitive and adaptive functioning with onset during the developmental period. Currently, treatment of intellectual ...
• Study of the role of Pap1 as a sensor of H2O2 and as a transcriptional activator of stress responses in Schizosaccharimyces pombe

  Calvo Arnedo, María Isabel, 1983- (Universitat Pompeu Fabra, 2012-12-21)

  En el laboratorio se utiliza como sistema modelo la levadura Schizosaccaromyces pombe para poder estudiar la respuesta a estrés oxidativo. Las dos rutas principales de respuesta a estrés oxidativo son las del factor de ...
• Reescrituras de la espiral: producción y recepción de Ubu roi de Alfred Jarry en Francia y su traducción y recepción en Argentina y España (1896-2016)

  Fólica, Laura (Universitat Pompeu Fabra, 2017-01-17)

  Esta tesis se centra en las reescrituras que la pieza teatral Ubu roi (1896) de Alfred Jarry experimentó tanto a partir de sus condiciones de producción y recepción en Francia como de sus traducciones y recepción en Argentina ...
• Investigating protein complexes potentially governing microtubule-dependent MBP mRNA distribution

  Jagiełło, Bogumiła, 1987- (Universitat Pompeu Fabra, 2018-12-05)

  La localització de molècules d'ARNm permet regular la síntesi de proteïnes localment i temporalment i això és vital per molts processos cel·lular fonamentals. A Oligodendròcits el transport de l'ARNm de la proteïna bàsica ...
• Deubiquitinating enzymes stabilizing Snail1 transcription factor : a role for USP27X in epithelial-to-mesenchymal transition

  Lambies Barjau, Guillem, 1990- (Universitat Pompeu Fabra, 2019-01-10)

  Cancer cells undergo epithelial-to-mesenchymal transition (EMT) to dissociate from the primary tumor and to survive to chemotherapy. EMT is controlled by Snail1, a transcriptional factor also required for the activation ...
• Control of anabolic steroids misuse in sport : potential of direct detection of phase II metabolites

  Esquivel López, Argitxu, 1989- (Universitat Pompeu Fabra, 2018-12-14)

  Anabolic androgenic steroids (AAS) are widely used by athletes to enhance sports performance. In this thesis, different studies were performed to evaluate the potential of the direct detection of phase II metabolites by ...
• Spindle assembly and the control of microtubule nucleation through NEDD1 phosphorylation

  Timón Pérez, Krystal, 1987- (Universitat Pompeu Fabra, 2019-12-18)

  During mitosis, the microtubules organize a bipolar spindle that segregates the chromosomes. In higher eukaryotes, these microtubules are nucleated through three different pathways involving the centrosomes (centrosomal ...
• La Mirada de Gong Li: estudio del sujeto actoral femenino en el cine chino

  Qi, Fang (Universitat Pompeu Fabra, 2019-01-29)

  La aparición de Gong Li en la pantalla simboliza una apertura revolucionaria en la representación del erotismo femenino en China, después de la denominada Revolución Cultural (1966-1976). En la presente tesis se demuestra ...
• Imágenes del horror en el cine contemporáneo: de lo irrepresentable a las imágenes del límite en el documental

  Hachero Hernández, Bruno (Universitat Pompeu Fabra, 2019-01-28)

  Esta tesis propone un estudio estético de la representación documental del horror en el cine contemporáneo, analizando cómo el cine articula modos puesta en escena para documentar genocidios, guerras, matanzas, crímenes o ...

Mostra'n més