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Recerca: tesis
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Tesis doctorals llegides a la UPF en format digital en accés obert.
Col·leccions d'aquesta comunitat
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Tesis Doctorals en Xarxa
Enviaments recents
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(Universitat Pompeu Fabra, 2016-11-28)The present thesis introduces the EPI-CT cohort study; a European collaborative effort aimed at quantifying the health risks of computed tomography (CT scan) radiation exposure during childhood and assesses the main ...
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(Universitat Pompeu Fabra, 2016-01-29)Aquest treball analitza la conceptualització i representació de la sepat dels dos ceptres-uas en el context de la Geografia sagrada d'Egipte des d'una perspectiva diacrònica a partir de la documentació papirològica i ...
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(Universitat Pompeu Fabra, 2016-12-20)High levels of physical activity have been related to better prognosis in patients with chronic obstructive pulmonary disease (COPD). However, so far no interventions have proven effective to modify physical activity in ...
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(Universitat Pompeu Fabra, 2018-04-10)We developed a computational framework implemented as an R package for generation, visualization and functional and differential analysis of epigenome maps. Methods are provided for integrating and comparing data from ...
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(Universitat Pompeu Fabra, 2018-06-08)The innovation of genomics has progressed at pace with the development of high-throughput DNA sequencing technologies. Prior to the outbreak of next-generation sequencing, retrieving genetic information was limited to a ...
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(Universitat Pompeu Fabra, 2018-05-22)Introduction: Occupational exposures are considered to be one of the newer and important risk factors for Chronic Obstructive Pulmonary Disease (COPD) besides tobacco smoking. However, the evidence mostly comes from smaller ...
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(Universitat Pompeu Fabra, 2018-02-16)In response to multiple internal and external stresses, yeast cells activate a common transcriptional response known as the Environmental Stress Response (ESR), which can be problematic in S phase, when DNA is being ...
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(Universitat Pompeu Fabra, 2018-03-20)El paradigma clàssic on un medicament interacciona amb un únic target biològic vinculat a una malaltia es posa en dubte. Actualment es reconeix que un medicament interacciona amb múltiples targets biològics i que aquests ...
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(Universitat Pompeu Fabra, 2016-11-14)microRNAs are small non-coding RNAs with crucial roles in gene regulation and whose contribution to animal evolution has been largely demonstrated. In this thesis we explored some functional consequences of microRNA sequence ...
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(Universitat Pompeu Fabra, 2017-12-04)Perfluoroalkyl substances (PFAS), such as perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA), are synthetic chemicals commonly used in industrial and commercial products including consumer care products, ...
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Big behavioral data analysis : computational methods for the study of continuous recordings behavior(Universitat Pompeu Fabra, 2016-11-08)New high-throughput behavioral systems enable the recording of continuous behavioral sequences with an unprecedented richness of signals and a deep temporal resolution. Automated systems offer neuroscience the opportunity ...
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(Universitat Pompeu Fabra, 2016-06-10)Aggregation of the amyloid-β (Aβ) peptide to form oligomers and amyloid fibrils is a central event in the pathogenesis of Alzheimer’s disease (AD). This thesis aims to provide a better understanding of Aβ toxicity and the ...
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(Universitat Pompeu Fabra, 2018-01-24)The evolutionary success of insects was particularly shaped by the innovation of the metamorphosis, especially by the transition from hemimetaboly to holometaboly. The mechanisms underlying this evolutionary transition ...
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(Universitat Pompeu Fabra, 2016-12-14)This thesis aims to study the determinants and trajectories of cognitive development, as well as the role of physical activity on cognitive and brain development in children aged 4 to 14 years old. We used data from two ...
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(Universitat Pompeu Fabra, 2017-01-20)This thesis provides evidence on the validity and diagnostic accuracy of generic and specific self-reported measures, developed from different psychometric approaches, to assess depression in the general population. First, ...
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(Universitat Pompeu Fabra, 2014-11-27)Recent epidemiological evidence on effect of air pollution and pregnancy outcomes is inconsistent. Differences in study design, sample size, population characteristics, control for confounders, air pollution measurements ...
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(Universitat Pompeu Fabra, 2012-12-14)The embryo of Caenorhabditis elegans is a model system in which development can be studied at single cell resolution. In this thesis I describe the use of a semi-automatic nuclear tracking algorithm to analyze cellular ...
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(Universitat Pompeu Fabra, 2016-05-09)Els pacients amb malaltia respiratòria crònica (MPOC) presenten manifestacions sistèmiques com disfunció muscular i alteracions nutricionals. Aquests tenen impacte en la qualitat de vida i la mortalitat. La seva rellevància ...
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(Universitat Pompeu Fabra, 2017-05-19)Macrophages are exquisite sensors of tissue homeostasis that can rapidly switch between pro- and anti-inflammatory or regulatory modes to respond to perturbations in the microenvironment. This functional plasticity involves ...
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(Universitat Pompeu Fabra, 2015-03-20)Translation control is a vital aspect of gene expression for both viruses and their cellular hosts. We have previously shown that the cellular mRNA decay activators Dhh1 and Lsm1-7 promote translation of positive-strand ...
