• Dynamical aspects of the regulation of bacterial proliferation

  Galera Laporta, Letícia, 1985- (Universitat Pompeu Fabra, 2019-02-08)

  Bacterial proliferation has been studied for more than 100 years, but our knowledge of the mechanisms that control its dynamical aspects is still very limited. In this Thesis we have studied, at both singlecell and population ...
• The Unresolved problems of peptide drug metabolism : Software-aided approach designed to analyze and predict cleavage sites for natural and synthetic peptides

  Radchenko, Tatiana L., 1984- (Universitat Pompeu Fabra, 2018-09-28)

  The work of this thesis aims to develop of a new workflow to predict potential Sites of Cleavage (SoCs) in new candidate peptide drugs. The main goal of this workflow is to understand the protease specificity rules from ...
• Deep sequencing approaches to investigate the dynamics and evolution of interaction networks of Candida pathogens and the human host

  Thuer, Ernst, 1986- (Universitat Pompeu Fabra, 2017-09-22)

  This thesis describes the application of Next Generation Sequencing, especially RNA sequencing, on the investigation of the pathogenic yeast Candida parapsilosis. Pathogenic yeasts of the Candida clade are one of the most ...
• Delineating a requirement for Survival of Motor Neuron (SMN) protein in skeletal muscle tissue

  Faleiro, Michelle R., 1987- (Universitat Pompeu Fabra, 2017-03-27)

  Spinal Muscular Atrophy (SMA) is an autosomal recessive neuromuscular disorder characterized by the degeneration of the lower motor neurons. It is caused by homozygous loss or mutations in the Survival Motor Neuron 1 (SMN1) ...
• Multi-feature machine learning analysis for an improved characterization of the cardiac mechanics

  Sánchez Martínez, Sergio (Universitat Pompeu Fabra, 2018-09-21)

  This thesis focuses on the development of machine learning tools to better characterize the cardiac anatomy and function in the context of heart failure, and in particular their extension to consider multiple parameters ...
• Polypharmacy in the elderly : data, models, and strategies

  Szabó, Viktória, 1986- (Universitat Pompeu Fabra, 2019-03-13)

  The demographic shift toward an aging population is increasing the burden of public health. On average, a person of 70 years can combine the intake of up to seven medications. The administration of multiple drugs at the ...
• Schlafen 12, a novel HIV restriction factor involved in latency

  Smutná, Katarína, 1991- (Universitat Pompeu Fabra, 2019-02-18)

  The process of HIV latency establishment and maintenance is not clearly understood. Homeostatic proliferation (HSP) is a major mechanism by which long-lived naive and memory CD4 T cells are maintained in vivo. HSP also ...
• Analytical strategies in imaging genetics : assessment of potential risk factors for neurodevelopmental domains

  Vilor Tejedor, Natàlia, 1988- (Universitat Pompeu Fabra, 2018-03-16)

  Imaging Genetics (IG) aims to test how genetic information influences brain structure and function, cognitive processes and complex neurodevelopmental domains, combining magnetic resonance imaging-based brain features and ...
• Implication of the disease-associated ORMDL3 in macrophage physiology

  Kiefer, Kerstin, 1986- (Universitat Pompeu Fabra, 2016-05-12)

  Genome-wide association studies linked increased ORMDL3 expression levels to several inflammatory diseases via single nucleotide polymorphisms. However, the pathophysiological mechanisms underlying this association are ...
• Exposure to air pollution and links with cardiometabolic health in low- and middle-income countries

  Curto Tirado, Ariadna, 1987- (Universitat Pompeu Fabra, 2019-03-01)

  The aims of this thesis are: 1) to evaluate the performance of low-cost air quality monitors to monitor long-term exposure in rural areas from low- and middle-income countries; 2) to identify the determinants of personal ...
• Genetic and epigenetic mechanisms regulating the G1-S transcriptional wave in fission yeast

  González Medina, Alberto, 1990- (Universitat Pompeu Fabra, 2019-03-01)

  The control of proper progression of eukaryotic cell cycle is essential if cells want to continue proliferating appropriately, and it is a conserve feature from yeast to human cells. One of the most important points of ...
• La vita degli oggetti: Walter Benjamin pioniere dei Material Studies

  Rezzonico, Sonia (Universitat Pompeu Fabra, 2019-02-26)

  Questo lavoro di ricerca ha come obbiettivo dimostrare in che modo l’approccio critico di Walter Benjamin possa essere considerato pioneristico rispetto ai Material Studies, ampia categoria di indagini contemporanee che ...
• The Diversity of union and fertility trajectories in the UK

  Di Nallo, Alessandro (Universitat Pompeu Fabra, 2019-02-21)

  This thesis explores the increasing complexity in the life course in the United Kingdom. The first article illustrates the association between parents’ socio-economic position and children’s transition to first union and ...
• Incorporating prosody into neural speech processing pipelines: applications on automatic speech transcription and spoken language machine translation

  Öktem, Alp (Universitat Pompeu Fabra, 2019-02-25)

  In this dissertation, I study the inclusion of prosody into two applications that involve speech understanding:~automatic speech transcription and spoken language translation. In the former case, I propose a method that ...
• The Origin of multicellularity in animals : a functional approach from unicellular perspective : Developing Capsaspora owczarzaki as an emerging model

  Ros i Rocher, Núria, 1991- (Universitat Pompeu Fabra, 2019-02-15)

  The origin of animal multicellularity is a major evolutionary question. Recent genome data from the closest extant unicellular relatives of animals revealed that they actually possess and express a complex repertoire of ...
• Maternidad y trabajo remunerado : utlización de las prestaciones sociales durante el embarazo en una muestra de trabajadoras de un hospital de Barcelona (España)

  Villar Vinuesa, Rocío, 1976- (Universitat Pompeu Fabra, 2019-02-20)

  Introducción: La protección social a las trabajadoras embarazadas comprende la incapacidad temporal por contingencia común (ITcc) y la prestación por riesgo durante el embarazo y/o la lactancia (PRE). Objetivos: 1) Examinar ...
• Más allá de la pantalla: prácticas fílmicas politizadas, colectivas, autogestionadas y de transformación social en Barcelona (2011-2018)

  Vargas Serpa, C. Gabriela (Universitat Pompeu Fabra, 2019-02-20)

  La presente investigación pretende abordar la relación entre cine y activismo. Más concretamente, la manera en que estos dos elementos se han articulado en la actual coyuntura -tras la última crisis económica y sus ...
• Detection of directional interactions between neurons from spike trains

  Malvestio, Irene (Universitat Pompeu Fabra, 2019-02-21)

  An important problem in neuroscience is the assessment of the connectivity between neurons from their spike trains. One recent approach developed for the detection of directional couplings between dynamics based on ...
• Strategies for creativity development in biomedical education through inquiry

  Rodríguez Fabià, Gemma, 1991- (Universitat Pompeu Fabra, 2019-02-22)

  Els avenços tecnològics i científics que s’han produït durant les últimes dècades han constituït la recerca biomèdica tal i com la coneixem avui en dia. Per poder afrontar els reptes que proposa la ciència, en un futur ...
• Pensamientos y conductas suicidas en universitarios españoles : frecuencia, factores de riesgo y protección

  Blasco Cubedo, Maria Jesús (Universitat Pompeu Fabra, 2021-02-22)

  El objetivo general de esta tesis es estudiar la frecuencia (prevalencia, incidencia y persistencia) de los pensamientos y conductas suicidas entre los universitarios españoles, así como aportar evidencia sobre su asociación ...

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