• Role of NK cells in the efficacy of anti-HER2 therapeutic antibodies in breast cancer : from biomarkers to functional checkpoints enhacing ADCC responses

  Cabo, Mariona, 1991- (Universitat Pompeu Fabra, 2019-11-08)

  HER2 overexpression accounts for approximately 15-20% of breast tumors, and mainstay therapy for these patients includes HER2-specific antibodies in combination with chemotherapy. Although the efficacy of anti-HER2 antibodies ...
• The Role of PHF19 in myeloid leukemia

  García Montolío, Marc, 1991- (Universitat Pompeu Fabra, 2019-11-04)

  Polycomb group (PcG) of proteins are a group of highly conserved epigenetic regulators involved in many biological functions such as embryonic development, stem cell self-renewal, cell proliferation, and cancer. PHD finger ...
• Political and discursive opportunities for institutional change: the case of marriage equality in the United States

  Mariani, Giulia (Universitat Pompeu Fabra, 2019-10-25)

  This dissertation employs a multi-method research design to analyze the political and discursive opportunities for gradual institutional change in the case of marriage equality in the American states. It comprises three ...
• The Interrelationship between migration and family behaviours: internal migration within China and international migration from China to the U.S.

  Nie, Wanli (Universitat Pompeu Fabra, 2019-10-31)

  The dissertation investigates the interrelationship between migration and family behaviours, marriage and fertility, in the Chinese context. I apply event history techniques using data from an ethno-survey, several ...
• Towards the improvement of decision tree learning: a perspective on search and evaluation

  Nunes, Cecília (Universitat Pompeu Fabra, 2019-10-25)

  Data mining and machine learning (ML) are increasingly at the core of many aspects of modern life. With growing concerns about the impact of relying on predictions we cannot understand, there is widespread agreement regarding ...
• From pixels to particles: multi-physics meshless model of the heart

  Lluc Álvarez, Èric (Universitat Pompeu Fabra, 2019-10-21)

  The functioning of the heart, which main role is pumping blood to the rest of the body, is the result of a complex combination of multi-scale physical processes from the molecular to the tissue level. The predominance of ...
• Electroporation and peripheral nerve stimulation

  Mercadal Cavaller, Borja (Universitat Pompeu Fabra, 2019-10-16)

  This thesis aimed at addressing questions within the fields of electroporation and peripheral nerve stimulation and, in particular, those that arise from the interaction between the two phenomenona. On the one hand, ...
• Argument realization: grammatical function and case assignment

  Yang, Fengrong (Universitat Pompeu Fabra, 2019-10-04)

  In this dissertation we propose a new mapping theory within the OT-LFG framework to account for the fact that in Catalan and other Romance languages, the direct argument of intransitive verbs (whether unaccusative or ...
• Neural machine translation evaluation & error analysis in a Spanish-Korean translation

  Kim, Ahrii (Universitat Pompeu Fabra, 2019-10-14)

  From RBMT to SMT and NMT, the MT field witnessed, first, a conceptual turn —from rule-based to data-base— and now, a technological turn —from MT algorithm to ML algorithm. Now that NMT became a new state of the art, this ...
• La Terminología de geografía en zapoteco: una nueva perspectiva para las escuelas de Oaxaca, México : la terminología zapoteca del siglo XXI

  Méndez Espinosa, Oscar (Universitat Pompeu Fabra, 2019-10-16)

  En esta tesis se presenta un estudio, realizado en el marco del sistema educativo de Oaxaca (México), sobre el léxico y la problemática que supone la falta de terminología en la lengua zapoteca, una lengua nativa de México. ...
• The Role of adult stem cells in tumor formation : mutations in Sox2+ cells induce lineage-specific proliferation

  Vázquez Ferrer, Eric, 1990- (Universitat Pompeu Fabra, 2017-11-10)

  It has been well-established that progressive accumulation of genetic mutations in proto-oncogenes and tumor suppressors induces cancer. However, the early molecular mechanisms leading to tumor initiation remain elusive. ...
• From networks to population-specific adaptations : studying positive selection in humans

  Dobón Berenguer, Begoña, 1987- (Universitat Pompeu Fabra, 2018-11-23)

  The evolution of the genome is driven, among other factors, by the composition of the genome, the functional output of the gene products, and by environmental pressures. Among the environmental factors, pathogens are one ...
• Sota el signe de l'Odissea: el viaggio in Italia del cinema modern: de Rossellini a El menyspreu

  Llorca, Vicenç, 1965- (Universitat Pompeu Fabra, 2015-10-30)

  Aquesta tesi pretén demostrar que l’Odissea constitueix un dels eixos vertebradors del cinema modern, ja que actua com a signe des del qual s’estableix un paradigma interpretatiu de la pròpia modernitat cinematogràfica i ...
• Exposición al humo ambiental de tabaco en población infantil : prevalencia, intensidad y factores asociados a la exposición en casa

  Arechavala Roe, Teresa, 1987- (Universitat Pompeu Fabra, 2018-11-08)

  El objetivo principal de esta tesis es estimar la prevalencia de exposición al humo ambiental de tabaco (HAT) en la población infantil y caracterizar la exposición en casa. Para ello, se han diseñado 4 estudios a partir ...
• Creactive subtitles: subtitling for ALL

  Sala Robert, Èlia (Universitat Pompeu Fabra, 2016-11-07)

  L’objectiu d’aquesta tesi és contribuir a la pràctica i la teoria de la subtitulació per a persones sordes (SPS), més concretament, per a nens i nenes sords. Després de l’anàlisi de les pràctiques de subtitulació actuals, ...
• Long-term exposure to greenspace and healthy ageing

  Keijzer, Carmen de, 1992- (Universitat Pompeu Fabra, 2019-10-25)

  As the world population is rapidly ageing and experiencing an ongoing urbanization, there is an emerging need for environments that are supportive of healthy ageing. Greenspace exposure may foster healthy ageing by promoting ...
• Teorías neoconstitucionalistas: un análisis de los constitucionalismos garantista, principialista e incorporacionista desde la cultura constitucional mexicana

  Vázquez Sánchez, Omar, (Universitat Pompeu Fabra, 2017-10-31)

  Este trabajo de investigación doctoral tiene por objeto analizar el «paradigma constitucionalista» y su relación con la cultura constitucional mexicana. En el paradigma constitucionalista están implicados dos fenómenos ...
• Collective phenomena in networks of spiking neurons with synaptic delays

  Devalle, Federico (Universitat Pompeu Fabra, 2019-05-03)

  A prominent feature of the dynamics of large neuronal networks are the synchrony-driven collective oscillations generated by the interplay between synaptic coupling and synaptic delays. This thesis investigates the emergence ...
• Bonobo evolution : from the perspective of genomes

  Han, Sojung, 1984- (Universitat Pompeu Fabra, 2019-10-16)

  Bonobos are an interesting species to study due to their unique evolutionary features such as a peaceful social nature and hypersexual behavior. The prolonged exaggerated sexual swelling in females is a notable difference ...
• Machine learning in structural biology and chemoinformatics : Driving drug discovery one epoch at a time

  Jiménez Luna, José, 1993- (Universitat Pompeu Fabra, 2019-10-24)

  Deep learning approaches have become increasingly popular in the last years thanks to their state-of the-art performance in fields such as computer vision and natural language understanding. The first goal of this thesis ...

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