• The Nucleolus : a connection between cell fate and tumorigenesis in colorectal cancer

  Morral Martínez, Clara, 1989- (Universitat Pompeu Fabra, 2017-07-17)

  El càncer de colon es caracteritza per presentar una composició cel·lular heterogènia en la qual només un subgrup de cèl·lules retenen la capacitat de contribuir en el manteniment i creixement del tumor. L‘investigació ...
• Empleo informal y desigualdades en salud en Chile : un enfoque de investigación integrado

  Ruiz Contreras, Marisol E., 1979- (Universitat Pompeu Fabra, 2018-05-22)

  Esta tesis tiene como objetivo principal comprender la relación entre el empleo informal y las desigualdades en salud en Chile desde una perspectiva integral. Considerando un abordaje abductivo que incorpora el enfoque de ...
• Evolución de las desigualdades socioeconómicas en la mortalidad prematura en los barrios de Barcelona

  Rodríguez Sanz, Maica, 1974- (Universitat Pompeu Fabra, 2017-12-21)

  El objetivo es analizar la evolución de las desigualdades socioeconómicas en mortalidad en los barrios de Barcelona, considerando los cambios poblacionales ocurridos. Se realizaron 3 estudios. Una revisión del uso del ...
• L'"agonia religiosa": mitopoiesi del "sentimiento spirituale" in Miguel de Unamuno

  Ricci, Raffaele (Universitat Pompeu Fabra, 2018-01-16)

  La agonía es el trato típico del hombre cristiano y representa la base de la pregunta religiosa del hombre de todos los tiempos. A través de la lectura de los textos unamunianos se pondrán “cara a cara” el pensamiento –y ...
• Insights into cytoplasmatic polyadenylation mediated by Drosophila Dicer-2

  Nadimpalli, Hima Priyanka, 1988- (Universitat Pompeu Fabra, 2017-12-11)

  Cytoplasmic polyadenylation is a widespread mechanism to control mRNA translation. In vertebrates, this mechanism requires two sequence elements in the 3’ UTR of substrate mRNAs, the U-rich Cytoplasmic Polyadenylation ...
• Socio-environmental exposures and neurodevelopmental disorders

  Suades González, Elisabet, 1981- (Universitat Pompeu Fabra, 2018-05-15)

  Introduction The influence of the environment, and its interplay with genetics, can account for up to half of the variance of neurodevelopmental disorders. In this thesis we reviewed previous literature on air pollution ...
• Unravelling new oncogenic functions of IKKα : towards a better understanding of colorectal carcinogenesis

  Colomer Montañà, Carlota, 1990- (Universitat Pompeu Fabra, 2017-12-21)

  Numerous studies have shown that the protein kinase IKKα is associated with cancer progression and metastasis in different models. However, the mechanisms underlying IKKα tumorigenic functions are poorly understood. We ...
• B cell ontogeny and stromal regulation of homeostatic antibody responses to commensal antigens in humans

  Bascones Gleave, Sabrina, 1985- (Universitat Pompeu Fabra, 2016-12-20)

  The spleen contains a unique subset of innate-like marginal zone (MZ) B cells that rapidly mount protective antibody responses to invasive encapsulated bacteria. Here we show that human splenic MZ B cells also mount ...
• Improving mathematical abilities by training numerical representations in children : the relation between learning mathematics and numerical cognition

  Ferres Forga, Nuria, 1968- (Universitat Pompeu Fabra, 2018-01-11)

  Improving mathematical abilities is important for educational systems and for society overall. We present two training regimes based on numerical representations. In Study 1, we show that a three-week computer-based ...
• Mechanisms and pathways involved in lung tumor development in patients with chronic respiratory conditions

  Mateu Jiménez, Mercè, 1990- (Universitat Pompeu Fabra, 2017-12-18)

  Chronic respiratory diseases, especially chronic obstructive pulmonary disease (COPD), and several molecular mechanisms may predispose to lung cancer (LC) development. Hypothesis: We hypothesized that different biological ...
• Effects of behavioural traits and the endogenous opioid system in neuropathic pain manifestations

  Lara Mayorga, Itzel Montserrat, 1982- (Universitat Pompeu Fabra, 2017-07-12)

  Neuropathic pain is a complex disorder that includes nociceptive, emotional and cognitive manifestations. This work was focused on how inter-individual variability and endogenous opioid system may be associated with these ...
• Characterization of the human sperm centrosome and its role in (in)fertility

  Amargant i Riera, Farners, 1990- (Universitat Pompeu Fabra, 2018-07-19)

  The centrosome is an essential organelle for the development of a new organism in animals. Upon fertilization the spermatozoon enters into the oocyte providing its basal body that converts into the first centrosome of the ...
• An Integrative approach to the systematics and evolution of some selected reptile groups from Arabia

  Simó Riudalbas , Marc, 1988- (Universitat Pompeu Fabra, 2018-07-20)

  Until relatively recently, many groups of terrestrial reptiles were considered to contain only few species vastly distributed across the Arabian Peninsula. This was mostly the result of the apparent morphological uniformity ...
• Genetic structure of North African human populations : A complex history of admixture

  Rubio Araúna, Lara, 1990- (Universitat Pompeu Fabra, 2017-12-14)

  North African populations show a complex genetic structure characterized by the admixture of at least four different components: Middle Eastern, sub-Saharan, European and autochthonous North African. However, there are few ...
• Genetic diversity and geographic patterns of human herpesvirus 4 and 6

  Telford, Marco, 1984- (Universitat Pompeu Fabra, 2017-12-19)

  This thesis focuses on Human herpesvirus 4 and 6, two ubiquitous viruses with a long list of putative disease associations, ranging from malignancies such as lymphomas and carcinomas to multiple sclerosis. To date, the ...
• Time-resolved systems analysis of virus infection fate regulation

  Pedragosa Marín, Mireia, 1988- (Universitat Pompeu Fabra, 2018-03-21)

  The processes and mechanisms of virus infection fate decisions that are the result of a dynamic virus - immune system interaction with either an efficient effector response and virus elimination or an alleviated immune ...
• Study of the neurobiological mechanisms involved in the development of eating and addictive disorders

  Gutiérrez Martos, Miriam, 1989- (Universitat Pompeu Fabra, 2018-06-08)

  Drug addiction and several eating disorders share striking similarities in their behavioural patterns triggered by the presence of neuronal alterations in the brain reward circuit. In this Thesis, we investigate the ...
• Study of the contribution of ORMDL3 to the cannabinoid antitumoral action

  García López, Roberto, 1991- (Universitat Pompeu Fabra, 2018-04-06)

  Genome-wide association studies have been very useful tools in the last years to relate genes and diseases. Thereby, single nucleotide polymorphisms have been linked to increased ORMDL3 expression and to different pathologies ...
• Using annotated discourse information of a RST Spanish-Chinese treebank for translation and language learning tasks

  Cao, Shuyuan (Universitat Pompeu Fabra, 2018-11-09)

  As one of the essential elements for Natural Language Processing (NLP), discourse has called much attention during recent years. Many studies explore the role of how discourse elements affect in different NLP research ...
• Chromatin-bound DYRK1A : promoter occupancy and implications in the regulation of ribosomal protein gene expression

  Barba Moreno, Laura, 1989- (Universitat Pompeu Fabra, 2018-06-22)

  DYRK1A (dual-specificity tyrosine-regulated kinase 1A) belongs to a conserved family of protein kinases present in all eukaryotes. DYRK1A is known to participate in cell proliferation and differentiation decisions and to ...

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