• Insights into cytoplasmatic polyadenylation mediated by Drosophila Dicer-2

  Nadimpalli, Hima Priyanka, 1988- (Universitat Pompeu Fabra, 2017-12-11)

  Cytoplasmic polyadenylation is a widespread mechanism to control mRNA translation. In vertebrates, this mechanism requires two sequence elements in the 3’ UTR of substrate mRNAs, the U-rich Cytoplasmic Polyadenylation ...
• Socio-environmental exposures and neurodevelopmental disorders

  Suades González, Elisabet, 1981- (Universitat Pompeu Fabra, 2018-05-15)

  Introduction The influence of the environment, and its interplay with genetics, can account for up to half of the variance of neurodevelopmental disorders. In this thesis we reviewed previous literature on air pollution ...
• Unravelling new oncogenic functions of IKKα : towards a better understanding of colorectal carcinogenesis

  Colomer Montañà, Carlota, 1990- (Universitat Pompeu Fabra, 2017-12-21)

  Numerous studies have shown that the protein kinase IKKα is associated with cancer progression and metastasis in different models. However, the mechanisms underlying IKKα tumorigenic functions are poorly understood. We ...
• B cell ontogeny and stromal regulation of homeostatic antibody responses to commensal antigens in humans

  Bascones Gleave, Sabrina, 1985- (Universitat Pompeu Fabra, 2016-12-20)

  The spleen contains a unique subset of innate-like marginal zone (MZ) B cells that rapidly mount protective antibody responses to invasive encapsulated bacteria. Here we show that human splenic MZ B cells also mount ...
• Improving mathematical abilities by training numerical representations in children : the relation between learning mathematics and numerical cognition

  Ferres Forga, Nuria, 1968- (Universitat Pompeu Fabra, 2018-01-11)

  Improving mathematical abilities is important for educational systems and for society overall. We present two training regimes based on numerical representations. In Study 1, we show that a three-week computer-based ...
• Mechanisms and pathways involved in lung tumor development in patients with chronic respiratory conditions

  Mateu Jiménez, Mercè, 1990- (Universitat Pompeu Fabra, 2017-12-18)

  Chronic respiratory diseases, especially chronic obstructive pulmonary disease (COPD), and several molecular mechanisms may predispose to lung cancer (LC) development. Hypothesis: We hypothesized that different biological ...
• Effects of behavioural traits and the endogenous opioid system in neuropathic pain manifestations

  Lara Mayorga, Itzel Montserrat, 1982- (Universitat Pompeu Fabra, 2017-07-12)

  Neuropathic pain is a complex disorder that includes nociceptive, emotional and cognitive manifestations. This work was focused on how inter-individual variability and endogenous opioid system may be associated with these ...
• Characterization of the human sperm centrosome and its role in (in)fertility

  Amargant i Riera, Farners, 1990- (Universitat Pompeu Fabra, 2018-07-19)

  The centrosome is an essential organelle for the development of a new organism in animals. Upon fertilization the spermatozoon enters into the oocyte providing its basal body that converts into the first centrosome of the ...
• An Integrative approach to the systematics and evolution of some selected reptile groups from Arabia

  Simó Riudalbas , Marc, 1988- (Universitat Pompeu Fabra, 2018-07-20)

  Until relatively recently, many groups of terrestrial reptiles were considered to contain only few species vastly distributed across the Arabian Peninsula. This was mostly the result of the apparent morphological uniformity ...
• Genetic structure of North African human populations : A complex history of admixture

  Rubio Araúna, Lara, 1990- (Universitat Pompeu Fabra, 2017-12-14)

  North African populations show a complex genetic structure characterized by the admixture of at least four different components: Middle Eastern, sub-Saharan, European and autochthonous North African. However, there are few ...
• Genetic diversity and geographic patterns of human herpesvirus 4 and 6

  Telford, Marco, 1984- (Universitat Pompeu Fabra, 2017-12-19)

  This thesis focuses on Human herpesvirus 4 and 6, two ubiquitous viruses with a long list of putative disease associations, ranging from malignancies such as lymphomas and carcinomas to multiple sclerosis. To date, the ...
• Study of the neurobiological mechanisms involved in the development of eating and addictive disorders

  Gutiérrez Martos, Miriam, 1989- (Universitat Pompeu Fabra, 2018-06-08)

  Drug addiction and several eating disorders share striking similarities in their behavioural patterns triggered by the presence of neuronal alterations in the brain reward circuit. In this Thesis, we investigate the ...
• Study of the contribution of ORMDL3 to the cannabinoid antitumoral action

  García López, Roberto, 1991- (Universitat Pompeu Fabra, 2018-04-06)

  Genome-wide association studies have been very useful tools in the last years to relate genes and diseases. Thereby, single nucleotide polymorphisms have been linked to increased ORMDL3 expression and to different pathologies ...
• Time-resolved systems analysis of virus infection fate regulation

  Pedragosa Marín, Mireia, 1988- (Universitat Pompeu Fabra, 2018-03-21)

  The processes and mechanisms of virus infection fate decisions that are the result of a dynamic virus - immune system interaction with either an efficient effector response and virus elimination or an alleviated immune ...
• Using annotated discourse information of a RST Spanish-Chinese treebank for translation and language learning tasks

  Cao, Shuyuan (Universitat Pompeu Fabra, 2018-11-09)

  As one of the essential elements for Natural Language Processing (NLP), discourse has called much attention during recent years. Many studies explore the role of how discourse elements affect in different NLP research ...
• Chromatin-bound DYRK1A : promoter occupancy and implications in the regulation of ribosomal protein gene expression

  Barba Moreno, Laura, 1989- (Universitat Pompeu Fabra, 2018-06-22)

  DYRK1A (dual-specificity tyrosine-regulated kinase 1A) belongs to a conserved family of protein kinases present in all eukaryotes. DYRK1A is known to participate in cell proliferation and differentiation decisions and to ...
• The Role of human reference translation in machine translation evaluation

  Fomicheva, Marina (Universitat Pompeu Fabra, 2017-07-18)

  Both manual and automatic methods for Machine Translation (MT) evaluation heavily rely on professional human translation. In manual evaluation, human translation is often used instead of the source text in order to avoid ...
• Hacia un modelo lingüístico de resumen automático de artículos médicos en español

  da Cunha Fanego, Iria (Universitat Pompeu Fabra, 2008-04-25)

  En esta tesis se presenta un modelo lingüístico de resumen automático de artículos médicos en español que aúna criterios basados en la estructura textual, en las unidades léxicas y la estructura discursiva y sintáctico-c ...
• Regulation of cell proliferation and differentiation by p38 MAPK in distinct physiopathological processes

  Maseres Javaloy, Pedro, 1984- (Universitat Pompeu Fabra, 2018-03-12)

  The p38 mitogen activated protein kinase (MAPK) has a crucial role in cells’ stress adaptation and survival. It also plays a role in physiological processes such as differentiation of skeletal muscle or in pathologies such ...
• GPCRmd - A web platform for collection, visualization and analysis of molecular dynamics data for G protein-coupled receptors : Bridging the gap between dynamics and receptor functionality

  Rodríguez Espigares, Ismael, 1990- (Universitat Pompeu Fabra, 2018-04-04)

  In this thesis, we present GPCRmd, an online repository with a submission system and visualization platform specifically designed for storing and providing easy access to molecular dynamics (MD) data of G protein-coupled ...

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