• Establishing an in vitro model for X chromosome reactivation in the germline

  Tarruell Pellegrin, Antonio,1990- (Universitat Pompeu Fabra, 2019-06-26)

  In female mammals, one of the X chromosomes is epigenetically inactivated through X chromosome Inactivation (XCI) during the epiblast differentiation. However, XCI is later specifically reversed in female germ cells by ...
• Metabarcoding of the 18S rRNA gene to uncover new molecular biodiversity in Metazoa and unicellular Opisthokonta

  Sánchez Arroyo, Alicia, 1989- (Universitat Pompeu Fabra, 2019-07-03)

  One of the main evolutionary transitions is the origin of animal and fungal multicellularity from single-cell ancestors. To address this change, it is necessary to study the extant unicellular relatives of animals (Metazoa) ...
• Single molecule localization microscopy reveals DNA compaction and nascent RNA structure in vivo

  Castells García, Àlvaro, 1991- (Universitat Pompeu Fabra, 2019-07-01)

  Chromatin organization and gene expression are interdependent. Previously, our group showed that nucleosomes form groups, termed clutches, whose size correlates with cell state. In this thesis, we carried out 3D, 2-color ...
• The Role of alternative splicing in mammalian preimplantation development

  Wyatt, Christopher Douglas Robert, 1988- (Universitat Pompeu Fabra, 2019-06-19)

  The transition from maternal to embryonic control is a crucial time in an organism’s life cycle, with an overhaul of the epigenetic marks, targeted mRNA degradation and the initiation of transcription. Yet, not only do ...
• Impact of Alzheimer's disease risk factors on white matter hyperintensities and cognition in cognitively unimpaired undividuals

  Brugulat Serrat, Anna, 1986- (Universitat Pompeu Fabra, 2019-06-21)

  White matter hyperintensities (WMH) have been associated with increased risk and progression of Alzheimer’s disease (AD). However, the range to which this association can be extended to AD risk factors and WMH burden in ...
• DYRK1A in cancer: good or evil : Defining properties of DYRK1A kinase as a novel tumor driver

  Boni, Jacopo, 1987- (Universitat Pompeu Fabra, 2019-06-20)

  DYRK (dual-specificity tyrosine-regulated kinases) is an evolutionary conserved family of protein kinases involved in the regulation of cellular processes, such as proliferation and survival, which play pivotal role in ...
• The Seller's right to cure under article 48 United Nations Convention on contracts for the international sale of goods

  Mirambell i Fargas, Miquel (Universitat Pompeu Fabra, 2017-07-18)

  In principle, contracts are enforceable mutually beneficial agreements. In the event of a breach of contract, many national, supranational, and international legal systems—as well as recent European harmonization projects ...
• Evaluación de la implementación a escala del Plan de Actividad Física, Deporte y Salud

  González Viana, Angelina, 1974- (Universitat Pompeu Fabra, 2018-12-13)

  En adultos, 10 minutos de actividad física (AF) tres veces al día, previene enfermedades no transmisibles y prolonga la esperanza de vida. El Plan de Actividad Física, Deporte y Salud (PAFES) busca incrementar el nivel de ...
• La Actuación del docente en la enseñanza presencial de la comprensión lectora en ELE: contextualización, desarrollo e integración de la comprensión lectora en el proceso de aprendizaje en el aula

  Alonso, Encina (Universitat Pompeu Fabra, 2019-01-18)

  En aquesta tesi ens centrem a estudiar l’actuació del docent d’ELE quan treballa textos a classe, tant abans com durant i després de la seva lectura. Per fer-ho, hem dut a terme una recerca etnogràfica, mitjançant mètodes ...
• Prostitución callejera, barrios y percepción de seguridad: un estudio en Barcelona

  Sobrino Garcés, Cristina (Universitat Pompeu Fabra, 2017-07-17)

  El objetivo de esta tesis doctoral es observar si la prostitución callejera influye en la percepción de seguridad. El ámbito de investigación se ha centrado en dos barrios de Barcelona en los que la prostitución callejera ...
• Essays on macroeconomic policy and business cycles

  Ou, Shenliang (Universitat Pompeu Fabra, 2019-07-03)

  This thesis consists of three chapters on macroeconomic policy and business cy-cles. In chapter 1, I estimate a time-varying structural VAR to study the effects of government spending shocks on a number of U.S. macroeconomic ...
• Essays in health and development economics

  Fernández Bazán, Fernando (Universitat Pompeu Fabra, 2019-06-12)

  In the first chapter, I analyze the consequences of increased prenatal exposure to marijuana on infant health in the US. I combine individual-level information on birth outcomes with novel data on the location and opening ...
• Essays on political economy of development

  Geng, Yining (Universitat Pompeu Fabra, 2019-06-21)

  This thesis consists of three chapters on topics in development economics. In the first chapter, I study the impact of family planning policies on gender-specific outcomes. I find positive impacts of the FPP on improv-ing ...
• Approaches to characterize structural properties of RNA

  Delli Ponti, Riccardo, 1987- (Universitat Pompeu Fabra, 2019-01-16)

  The secondary structure of an RNA molecule is fundamental for its function. However, structural conservation and the structure of RNA in vivo are still poorly understood. Data from recent high-throughput experiments can ...
• Fundamentos filosóficos de la doctrina del margen de apreciación del Tribunal Europeo de Derechos Humanos

  Andrade Moreno, Marcos Antonio (Universitat Pompeu Fabra, 2017-07-12)

  The purpose of this research is to elucidate the philosophical foundations of the Margin of Appreciation Doctrine of the European Court of Human Rights. For this, two basic problems are distinguished: the conceptual problem ...
• Deubiquitinating enzymes stabilizing Snail1 transcription factor : a role for USP27X in epithelial-to-mesenchymal transition

  Lambies Barjau, Guillem, 1990- (Universitat Pompeu Fabra, 2019-01-10)

  Cancer cells undergo epithelial-to-mesenchymal transition (EMT) to dissociate from the primary tumor and to survive to chemotherapy. EMT is controlled by Snail1, a transcriptional factor also required for the activation ...
• El Gobierno corporativo de la empresa en crisis: a propósito del estatuto de los administradores y de las normas de prelación crediticia respecto al cambio de control

  Ara Triadú, Carlos (Universitat Pompeu Fabra, 2017-07-10)

  Este trabajo analiza la insolvencia como un problema de gobierno corporativo que puede aparecer cuando el desequilibrio financiero reduce el valor razonable de la empresa a una cifra inferior al pasivo exigible de la ...
• The Dynamics of hippocampal encoding: beyond the spatial metaphor

  Santos-Pata, Diogo (Universitat Pompeu Fabra, 2018-07-10)

  Every animal on our planet wanders around when looking for something. Whether it is in search of food, a mate, or home, navigation is one of the most performed cognitive behaviors in Nature. Nevertheless, our understanding ...
• Grounding body ownership and language in action: evidence from healthy and damaged brains

  Grechuta, Klaudia (Universitat Pompeu Fabra, 2019-07-05)

  Contrary to the classical theory of mind, largely inspired by dualism, the theoretical framework of embodiment emphasizes the constitutive role of the body in the process of cognition. This view also referred to as the ...
• Learner perceptions of emotions in the foreign language classroom: a one-year study of the connections between anxiety, enjoyment, performance and individual differences in adult education

  Motiei, Golnaz (Universitat Pompeu Fabra, 2019-05-28)

  Emotions, both positive and negative, play an important role in foreign language learning. However, whereas a great number of studies have investigated the construct and sources of negative emotions such as foreign language ...

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