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Adherence to Mediterranean Diet and All-Cause Mortality After an Episode of Acute Heart Failure: Results of the MEDIT-AHF Study

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dc.contributor.author Miró, Òscar
dc.contributor.author Estruch, Ramón
dc.contributor.author Martín-Sánchez, Francisco J.
dc.contributor.author Gil, Víctor
dc.contributor.author Jacob, Javier
dc.contributor.author Herrero-Puente, Pablo
dc.contributor.author Herrera Mateo, Sergio
dc.contributor.author Aguirre Tejedo, Alfons
dc.contributor.author Andueza, Juan A.
dc.contributor.author Llorens, Pere
dc.contributor.author ICA-SEMES Research Group
dc.date.accessioned 2018-11-22T08:33:02Z
dc.date.issued 2018
dc.identifier.citation Miró Ò, Estruch R, Martín-Sánchez FJ, Gil V, Jacob J, Herrero-Puente P. et al. Adherence to Mediterranean Diet and All-Cause Mortality After an Episode of Acute Heart Failure: Results of the MEDIT-AHF Study. JACC Heart Fail. 2018 Jan;6(1):52-62. DOI: 10.1016/j.jchf.2017.09.020
dc.identifier.issn 2213-1779
dc.identifier.uri http://hdl.handle.net/10230/35817
dc.description.abstract OBJECTIVES: The authors sought to evaluate clinical outcomes of patients after an episode of acute heart failure (AHF) according to their adherence to the Mediterranean diet (MedDiet). BACKGROUND: It has been proved that MedDiet is a useful tool in primary prevention of cardiovascular diseases. However, it is unknown whether adherence to MedDiet is associated with better outcomes in patients who have already experienced an episode of AHF. METHODS: We designed a prospective study that included consecutive patients diagnosed with AHF in 7 Spanish emergency departments (EDs). Patients were included if they or their relatives were able to answer a 14-point score of adherence to the MedDiet, which classified patients as adherents (≥9 points) or nonadherents (≤8 points). The primary endpoint was all-cause mortality at the end of follow-up, and secondary endpoints were 1-year ED revisit without hospitalization, rehospitalization, death, and a combined endpoint of all these variables for patients discharged after the index episode. Unadjusted and adjusted hazard ratios (HRs) were calculated. RESULTS: We included 991 patients (mean age of 80 ± 10 years, 57.8% women); 523 (52.9%) of whom were adherent to the MedDiet. After a mean follow-up period of 2.1 ± 1.3 years, no differences were observed in survival between adherent and nonadherent patients (HR of adherents [HRadh] = 0.86; 95% confidence interval [CI]: 0.73 to 1.02). The 1-year cumulative ED revisit for the whole cohort was 24.5% (HRadh = 1.10; 95% CI: 0.84 to 1.42), hospitalization 43.7% (HRadh = 0.74; 95% CI: 0.61 to 0.90), death 22.7% (HRadh = 1.05; 95% CI: 0.8 to 1.38), and combined endpoint 66.8% (HRadh = 0.89; 95% CI: 0.76 to 1.04). Adjustment by age, hypertension, peripheral arterial disease, previous episodes of AHF, treatment with statins, air-room pulsioxymetry, and need for ventilation support in the ED rendered similar results, with no statistically significant differences in mortality (HRadh = 0.94; 95% CI: 0.80 to 1.13) and persistence of lower 1-year hospitalization for adherents (HRadh = 0.76; 95% CI: 0.62 to 0.93). CONCLUSIONS: Adherence to the MedDiet did not influence long-term mortality after an episode of AHF, but it was associated with decreased rates of rehospitalization during the next year.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartof JACC Heart Failure. 2018 Jan;6(1):52-62
dc.rights © Elsevier http://dx.doi.org/10.1016/j.jchf.2017.09.020
dc.subject.other Dieta -- Mediterrània, Regió de la
dc.subject.other Cor -- Malalties
dc.title Adherence to Mediterranean Diet and All-Cause Mortality After an Episode of Acute Heart Failure: Results of the MEDIT-AHF Study
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1016/j.jchf.2017.09.020
dc.subject.keyword Mediterranean diet
dc.subject.keyword Acute heart failure
dc.subject.keyword Cardiovascular disease
dc.subject.keyword Diet
dc.subject.keyword Heart failure
dc.subject.keyword Outcome
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/acceptedVersion


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