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Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project

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dc.contributor.author De Pascale, Gennaro
dc.contributor.author Álvarez Lerma, Francisco
dc.contributor.author Marín Corral, Judith
dc.contributor.author Masclans Enviz, Joan Ramon
dc.contributor.author Martín-Loeches, Ignacio
dc.date.accessioned 2018-05-17T07:23:46Z
dc.date.available 2018-05-17T07:23:46Z
dc.date.issued 2017
dc.identifier.citation De Pascale G, Ranzani OT, Nseir S, Chastre J, Welte T, Antonelli M. et al. Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project. ERJ Open Res. 2017 Nov 17;3(4): 00092-2017. DOI: 10.1183/23120541.00092-2017
dc.identifier.issn 2312-0541
dc.identifier.uri http://hdl.handle.net/10230/34672
dc.description.abstract The clinical course of intensive care unit (ICU) patients may be complicated by a large spectrum of lower respiratory tract infections (LRTI), defined by specific epidemiological, clinical and microbiological aspects. A European network for ICU-related respiratory infections (ENIRRIs), supported by the European Respiratory Society, has been recently established, with the aim at studying all respiratory tract infective episodes except community-acquired ones. A multicentre, observational study is in progress, enrolling more than 1000 patients fulfilling the clinical, biochemical and radiological findings consistent with a LRTI. This article describes the methodology of this study. A specific interest is the clinical impact of non-ICU-acquired nosocomial pneumonia requiring ICU admission, non-ventilator-associated LRTIs occurring in the ICU, and ventilator-associated tracheobronchitis. The clinical meaning of microbiologically negative infectious episodes and specific details on antibiotic administration modalities, dosages and duration are also highlighted. Recently released guidelines address many unresolved questions which might be answered by such large-scale observational investigations. In light of the paucity of data regarding such topics, new interesting information is expected to be obtained from our network research activities, contributing to optimisation of care for critically ill patients in the ICU
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher European Respiratory Society
dc.rights This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.other Medicina intensiva
dc.subject.other Insuficiència respiratòria
dc.subject.other Infeccions nosocomials -- Prevenció
dc.title Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project
dc.type info:eu-repo/semantics/article
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion


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