Welcome to the UPF Digital Repository

Assessment of salivary cotinine concentration among general non-smokers population: Before and after Spanish smoking legislations

Show simple item record

dc.contributor.author Lidón-Moyano, Cristina
dc.contributor.author Fu, Marcela
dc.contributor.author Pérez Ortuño, Raúl, 1976-
dc.contributor.author Ballbé, Montse
dc.contributor.author Sampedro-Vida, Marc
dc.contributor.author Martín-Sánchez, Juan Carlos
dc.contributor.author Pascual Esteban, José A.
dc.contributor.author Fernández, Esteve
dc.contributor.author Martínez-Sánchez, Jose M.
dc.date.accessioned 2018-04-27T07:53:10Z
dc.date.issued 2017
dc.identifier.citation Lidón-Moyano C, Fu M, Perez-Ortuño R, Ballbè M, Sampedro-Vida M, Martín-Sánchez JC. Et al. Assessment of salivary cotinine concentration among general non-smokers population: Before and after Spanish smoking legislations. Cancer Epidemiol. 2017 Dec;51:87-91. DOI: 10.1016/j.canep.2017.10.011
dc.identifier.issn 1877-7821
dc.identifier.uri http://hdl.handle.net/10230/34503
dc.description.abstract BACKGROUND: In Spain, two smoke-free laws have been passed (Law 28/2005 and Law 42/2010).This study evaluates the association between Spanish smoking legislations and the second-hand smoke (SHS) exposure in an adult non-smoking population cohort in Barcelona (Spain). METHODS: This is a longitudinal study, before and after the implementation of two national smoking bans, in a representative sample of adults (≥16years old) from Barcelona (Spain) surveyed in 2004-2005 and followed up in 2013-2014 (n=736). We only analyzed non-smokers (n=397). We obtained 9ml of saliva sample for analysis of cotinine, a biomarker of recent tobacco exposure. We calculated geometric means of salivary cotinine concentration and their geometric standard deviation. We used linear mixed effect models, with individuals as random effects, to model the percentage change in salivary cotinine concentration and their 95% confidence intervals. RESULTS: The percentage of participants with saliva samples with measurable concentrations of cotinine fell from 92.4% to 64.2% after both Spanish smoking legislations. The geometric mean of salivary cotinine concentration significantly decreased 88% (from 0.98ng/mL to 0.12ng/mL, p<0.001) after the implementation of the two Spanish smoke-free legislations. The decrease of the GM salivary cotinine concentration was statistically significant independently of the sociodemographic variables. CONCLUSION: There was a large reduction in the salivary cotinine concentration among adult non-smokers and higher cotinine concentrations among those declaring exposure to SHS at home after both legislations. Moreover, after both Spanish smoke-free laws salivary cotinine concentration was homogenized according to sociodemographic variables
dc.description.sponsorship This project was co-funded by the Instituto de Salud Carlos III, Subdirección General de Evaluación, Government of Spain (RTICC RD12/0036/0053, PI12/01114 and PI12/01119), and the Ministry of Universities and Research, Government of Catalonia (grant 2014SGR999 and 2014SGR00680) from the Government of Catalonia, and co-funded by ISCIII-Subdirección General de Evaluación and by FEDER funds/European Regional Development Fund (ERDF) −a way to build Europe-. This work was also partially funded by the European Union’s Horizon 2020 Research and Innovation Programme (The TackSHS Project; grant agreement: 681040).
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartof Cancer Epidemiology. 2017 Dec;51:87-91
dc.rights © Elsevier http://dx.doi.org/10.1016/j.canep.2017.10.011
dc.subject.other Tabaquisme
dc.subject.other Legislació - Espanya
dc.title Assessment of salivary cotinine concentration among general non-smokers population: Before and after Spanish smoking legislations
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1016/j.canep.2017.10.011
dc.subject.keyword Biomarker
dc.subject.keyword Cotinine
dc.subject.keyword Secondhand smoke
dc.subject.keyword Smoke-free legislation
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/681040
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/acceptedVersion

Thumbnail

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account

Statistics

In collaboration with Compliant to Partaking