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Community-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus in critically-ill patients: systematic review

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dc.contributor.author Carballo Martínez, Núria
dc.contributor.author De Antonio Cuscó, Marta
dc.contributor.author Echeverría Esnal, Daniel
dc.contributor.author Luque Pardos, Sònia
dc.contributor.author Salas Sanchez, Esther
dc.contributor.author Grau Cerrato, Santiago
dc.date.accessioned 2018-01-11T08:20:52Z
dc.date.available 2018-01-11T08:20:52Z
dc.date.issued 2017
dc.identifier.citation Carballo N, De Antonio-Cuscó M, Echeverría-Esnal D, Luque S, Salas E, Grau S. Community-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus in critically-ill patients: systematic review. Farm Hosp. 2017 Mar 1;41(2):187-203. doi: 10.7399/fh.2017.41.2.10591
dc.identifier.issn 1130-6343
dc.identifier.uri http://hdl.handle.net/10230/33612
dc.description.abstract INTRODUCTION: Community-acquired pneumonia (CAP) is associated with high morbidity and mortality rates. Despite methicillin-resistant Staphylococcus aureus (MRSA) having often been associated with nosocomial pneumonia, the condition of some MRSA CAP patients is severe enough to warrant their being admitted to ICU. OBJECTIVE: The purpose of this study is to conduct a systematic review of the literature on antibiotic treatment of MRSA CAP in critically-ill patients. MATERIAL AND METHODS: An online search was conducted for locating articles on MRSA CAP in critically ill patients. Relevant publications were identified in PUBMED, the BestPractice database, UpToDate database and the Cochrane Library for articles published in English within the December 2001 - April 2016 time frame. RESULTS: A total of 70 articles were found to have been published, 13 (18.8%) having been included and 57 (81.4%) excluded. Cohort studies were predominant, having totaled 16 in number (20.7%) as compared to one sole cross-sectional study (3.5%). CONCLUSIONS: The experience in the treatment of MRSA CAP in patients requiring admission to ICU is quite limited. Vancomycin or linezolid seem to be the treatments of choice for MRSA CAP, although there not be any specific recommendation in this regard. It may be useful to use alternative routes, such as administration via aerosolized antibiotics, continuous infusion or in association with other antibiotics
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Sociedad Española de Farmacia Hospitalaria
dc.relation.ispartof Farmacia Hospitalaria. 2017 Mar 1;41(2):187-203
dc.rights Los artículos publicados en esta revista se distribuyen con la licencia:https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.other Pneumònia -- Tractament
dc.title Community-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus in critically-ill patients: systematic review
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.7399/fh.2017.41.2.10591
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion

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