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A novel statistical analysis and interpretation of flow cytometry data

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dc.contributor.author Banks, H. Thomas
dc.contributor.author Kapraun, Dustin F.
dc.contributor.author Thompson, W. Clayton
dc.contributor.author Peligero Cruz, Cristina, 1986-
dc.contributor.author Argilaguet Marqués, Jordi, 1977-
dc.contributor.author Meyerhans, Andreas
dc.date.accessioned 2015-11-30T15:17:37Z
dc.date.available 2015-11-30T15:17:37Z
dc.date.issued 2013
dc.identifier.citation Banks HT, Kapraun DF, Thompson WC, Peligero Cruz C, Argilaguet Marqués J, Meyerhans A. A novel statistical analysis and interpretation of flow cytometry data. J Biol Dyn. 2013;7:96-132. DOI: 10.1080/17513758.2013.812753
dc.identifier.issn 1751-3758
dc.identifier.uri http://hdl.handle.net/10230/25267
dc.description.abstract A recently developed class of models incorporating the cyton model of population generation structure into a conservation-based model of intracellular label dynamics is reviewed. Statistical aspects of the data collection process are quantified and incorporated into a parameter estimation scheme. This scheme is then applied to experimental data for PHA-stimulated CD4+T and CD8+T cells collected from two healthy donors. This novel mathematical and statistical framework is shown to form the basis for accurate, meaningful analysis of cellular behaviour for a population of cells labelled with the dye carboxyfluorescein succinimidyl ester and stimulated to divide.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Taylor & Francis (Routledge)
dc.relation.ispartof Journal of biological dynamics. 2013;7:96-132
dc.rights © 2013 Taylor & Francis. This is an electronic version of an article published in Journal of biological dynamics. 2013. 7: 96-132. Journal of biological dynamics is available online at: www.tandfonline.com/doi/pdf/10.1080/17513758.2013.812753
dc.subject.other Cèl·lules T
dc.subject.other Estadística matemàtica
dc.title A novel statistical analysis and interpretation of flow cytometry data
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1080/17513758.2013.812753
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion


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