dc.contributor.author |
Banks, H. Thomas |
dc.contributor.author |
Kapraun, Dustin F. |
dc.contributor.author |
Thompson, W. Clayton |
dc.contributor.author |
Peligero Cruz, Cristina, 1986- |
dc.contributor.author |
Argilaguet Marqués, Jordi, 1977- |
dc.contributor.author |
Meyerhans, Andreas |
dc.date.accessioned |
2015-11-30T15:17:37Z |
dc.date.available |
2015-11-30T15:17:37Z |
dc.date.issued |
2013 |
dc.identifier.citation |
Banks HT, Kapraun DF, Thompson WC, Peligero Cruz C, Argilaguet Marqués J, Meyerhans A. A novel statistical analysis and interpretation of flow cytometry data. J Biol Dyn. 2013;7:96-132. DOI: 10.1080/17513758.2013.812753 |
dc.identifier.issn |
1751-3758 |
dc.identifier.uri |
http://hdl.handle.net/10230/25267 |
dc.description.abstract |
A recently developed class of models incorporating the cyton model of population generation structure into a conservation-based model of intracellular label dynamics is reviewed. Statistical aspects of the data collection process are quantified and incorporated into a parameter estimation scheme. This scheme is then applied to experimental data for PHA-stimulated CD4+T and CD8+T cells collected from two healthy donors. This novel mathematical and statistical framework is shown to form the basis for accurate, meaningful analysis of cellular behaviour for a population of cells labelled with the dye carboxyfluorescein succinimidyl ester and stimulated to divide. |
dc.format.mimetype |
application/pdf |
dc.language.iso |
eng |
dc.publisher |
Taylor & Francis (Routledge) |
dc.relation.ispartof |
Journal of biological dynamics. 2013;7:96-132 |
dc.rights |
© 2013 Taylor & Francis. This is an electronic version of an article published in Journal of biological dynamics. 2013. 7: 96-132. Journal of biological dynamics is available online at: www.tandfonline.com/doi/pdf/10.1080/17513758.2013.812753 |
dc.subject.other |
Cèl·lules T |
dc.subject.other |
Estadística matemàtica |
dc.title |
A novel statistical analysis and interpretation of flow cytometry data |
dc.type |
info:eu-repo/semantics/article |
dc.identifier.doi |
http://dx.doi.org/10.1080/17513758.2013.812753 |
dc.rights.accessRights |
info:eu-repo/semantics/openAccess |
dc.type.version |
info:eu-repo/semantics/publishedVersion |