• The genetics of East African populations: a Nilo-Saharan component in the African genetic landscape [supplementary information]

  Dobon, Begoña; Hassan, Hisham Y.; Laayouni, Hafid, 1968-; Luisi, Pierre, 1985-; Ricaño Ponce, Isis; Zhernakova, Alexandra; Wijmenga, Cisca; Tahir, Hanan; Comas, David, 1969-; Netea, Mihai G; Bertranpetit, Jaume, 1952- (Universitat Pompeu Fabra, 2018-04-27)
• Quantitative predictions of protein interactions with long noncoding RNAs

  Cirillo, Davide (Universitat Pompeu Fabra, 2016)

  Long noncoding RNAs (lncRNAs, which comprise 68% of the human transcriptome with average length of 1,000 nt) interact with various RNA-binding proteins (RBPs) to mediate cellular functions. Here we introduce Global Score ...
• Performance of low-cost monitors to assess household air pollution [dataset]

  Curto Tirado, Ariadna, 1987-; Donaire González, David; Barrera Gómez, Jose; Marshall, Julian D.; Nieuwenhuijsen, Mark J.; Wellenius, Gregory A.; Tonne, Cathryn (Universitat Pompeu Fabra, 2016-02-22)

  Raw data of PM2.5 and CO from an indoor wood-combustion experiment. We evaluated the performance of two low-cost sensors measuring fine particulate matter (PM2.5) (HAPEX Nano, Climate Solutions Consulting, and TZOA-R Model ...
• Intogen - Catalog of driver mutations

  Tamborero Noguera, David; Rubio Pérez, Carlota; Déu Pons, Jordi; Schroeder, Michael Philipp, 1986-; Vivancos Prellezo, Ana; Rovira Guerín, Ana; Tusquets, Ignasi; Albanell Mestres, Joan; Tabernero Cartula, Josep; Dienstman, Rodrigo; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2016-10)

  This database contains the results of the driver analysis performed by the Cancer Genome Interpreter across 6,792 exomes of a pan-cancer cohort of 28 tumor types. Validated oncogenic mutations are identified according to ...
• TCGI prescription

  Tamborero Noguera, David; Rubio Pérez, Carlota; Déu Pons, Jordi; Schroeder, Michael Philipp, 1986-; Vivancos Prellezo, Ana; Rovira Guerín, Ana; Tusquets, Ignasi; Albanell Mestres, Joan; Rodon, Jordi; Tabernero Cartula, Josep; Dienstman, Rodrigo; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2016-10)

  CGI drug prescription assigns targeted drugs to a tumor, based on its genomic alterations, according different levels of evidence (from pre-clinical assays to clinical guidelines).
• OncodriveMUT

  Tamborero Noguera, David; Rubio Pérez, Carlota; Déu Pons, Jordi; Schroeder, Michael Philipp, 1986-; Vivancos Prellezo, Ana; Rovira Guerín, Ana; Tusquets, Ignasi; Albanell Mestres, Joan; Rodon, Jordi; Tabernero Cartula, Josep; Dienstman, Rodrigo; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2016-01)

  Bioinformatics method to identify individual driver mutations.
• iDGP

  Furney, Simon J.; Albà Soler, Mar; López Bigas, Núria (Universitat Pompeu Fabra, 2006-07)

  Database of human genes prioritized for their probability of involvement in dominant or recessive hereditary diseases.
• Evolvavility

  López Bigas, Núria; De, Subhajyoti; Teichmann, Sarah A. (Universitat Pompeu Fabra, 2007-10)

  Mutations, genes and pathways involved in tumorigenesis across 4,623 cancer genomes/exomes from 13 cancer sites. IntOGen-mutations identifies cancer drivers across tumor types. Nature Methods 10, 2013, doi:10.1038/nmeth.2642
• funcSTAR

  Shikhagaie, Medya; López Bigas, Núria (Universitat Pompeu Fabra, 2007-10)

  Web tool for the selection of SNPs from the STAR project with potential functional effect.
• CGProp

  Furney, Simon J.; Madden, Stephen F.; Kisiel, Tomasz A.; Higgins, Desmond G.; López Bigas, Núria (Universitat Pompeu Fabra, 2007-12)

  Cancer gene properties.
• RBP2

  López Bigas, Núria; Kisiel, Tomasz A.; DeWaal, Dannielle C.; Holmes, Katherine B.; Volkert, Tom L.; Gupta, Sumeet; Love, Jennifer; Murray, Heather L.; Young, Richard A.; Benevolenskaya, Elizaveta V. (Universitat Pompeu Fabra, 2008-09)

  Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation.
• IntOGen - Arrays

  Gundem, Gunes; Pérez Llamas, Christian, 1976-; Jené i Sanz, Alba, 1984-; Kedzierska, Anna; Islam, Abul, 1978-; Déu Pons, Jordi; Furney, Simon J.; López Bigas, Núria (Universitat Pompeu Fabra, 2010-02)

  Genes and pathways affected by expression and copy number changes in tumors across projects and cancer types.
• p27

  Pippa, Raffaella; Espinosa Blay, Lluís; Gundem, Gunes; Garcia Escudero, Ramon; Dominguez, Ana; Orlando, S.; Gallastegui, E.; Saiz, Cristina; Besson, Arnaud; Pujol, Maria Jesus; López Bigas, Núria; Paramio, Jesus M.; Bigas Salvans, Anna; Bachs Valldeneu, Oriol (Universitat Pompeu Fabra, 2011-12)

  The cyclin-cdk (cyclin-dependent kinase) inhibitor p27(Kip1) (p27) has a crucial negative role on cell cycle progression. In addition to its classical role as a cyclin-cdk inhibitor, it also performs cyclin-cdk-independent ...
• SVGMap

  Rafael Palou, Xavier; Schroeder, Michael Philipp, 1986-; López Bigas, Núria (Universitat Pompeu Fabra, 2012-01)

  The aim of SVGMap is helping in the visualisation of experimental data which are associated with some graphical representation. Thus SVGMap browser allows to generate images with colored areas corresponding to the chosen ...
• Oncodrive-CIS

  Tamborero Noguera, David; López Bigas, Núria; González-Pérez, Abel (Universitat Pompeu Fabra, 2013-02)

  Oncodrive-CIS is a method aimed to identify those copy number alterations (CNAs) leading to larger in cis expression changes that may be useful in elucidating the role of these aberrations in cancer. This is based on the ...
• IntOGen - Cancer driver database (2013)

  González-Pérez, Abel; Pérez Llamas, Christian, 1976-; Déu Pons, Jordi; Tamborero Noguera, David; Schroeder, Michael Philipp, 1986-; Jené i Sanz, Alba, 1984-; Santos, Alberto; López Bigas, Núria (Universitat Pompeu Fabra, 2013-05)

  Mutations, genes and pathways involved in tumorigenesis across 4,623 cancer genomes/exomes from 13 cancer sites. IntOGen-mutations identifies cancer drivers across tumor types. Nature Methods 10, 2013, doi:10.1038/nmeth.2642
• IntOGen - TCGA pan-cancer12 high confidence drivers

  Tamborero Noguera, David; González-Pérez, Abel; Pérez Llamas, Christian, 1976-; Déu Pons, Jordi; Kandoth, Cyriac; Reimand, Jüri; Lawrence, Michael S.; Getz, Gad; Bader, Gary D.; Ding, Li; López Bigas, Núria (Universitat Pompeu Fabra, 2013-10)

  This file lists the High Confidence Drivers identified as part of the pan-cancer12 initiative, published in the paper Comprehensive identification of mutational cancer driver genes across 12 tumor types" Scientific Reports ...
• IntOGen - Cancer Drivers Actionability Database

  Rubio Pérez, Carlota; Tamborero Noguera, David; Schroeder, Michael Philipp, 1986-; Antolín Hernández, Albert, 1984-; Déu Pons, Jordi; Pérez Llamas, Christian, 1976-; Mestres i López, Jordi; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2015-03)

  This database contains data on the interactions with therapeutic agents an driver genes contained in Cancer Drivers Database (2014.12). It characterizes the interacting therapeutic agents in terms of clinical phase and ...
• C10-HDAC7

  Barneda Zahonero, Bruna; Román González, Lidia; Collazo, Olga; Rafati, Haleh; Islam, Abul, 1978-; Bussmann, Lars; Di Tullio, Alessandro, 1982-; Andrés, Luisa De; Graf, T. (Thomas); López Bigas, Núria; Mahmoudi, Tokameh; Parra, Maribel (Universitat Pompeu Fabra, 2013-05)

  HDAC7 is a repressor of myeloid genes whose downregulation in pre-B cells is required for transdifferentiation into macrophages.
• IntOGen - Cancer Drivers Database (2014)

  Rubio Pérez, Carlota; Tamborero Noguera, David; Schroeder, Michael Philipp, 1986-; Antolín Hernández, Albert, 1984-; Déu Pons, Jordi; Pérez Llamas, Christian, 1976-; Mestres i López, Jordi; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2015-03)

  This database contains information on the genes identified as drivers in Rubio-Perez and Tamborero et al. (2015). It contains information on driver identification at mutational, CNA and gene fusion level. Additional ancillary ...

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